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In general, Medicare plans do not cover this drug. This drug will likely be quite expensive and you may want to consider using a USARx discount instead of Medicare to find the best price for this prescription.It depends. Which coverage stage are you in? Click on a tab below…
$125 – $162
In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.
Here are some ways that may lower the cost of your linzess prescription.
If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.
Linzess (linaclotide) works by increasing the secretion of chloride and water in the intestines, which can soften stools and stimulate bowel movements.
Linzess is a prescription medicine used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in adults who have had constipation as the main symptom. The safety and effectiveness of Linzess has not been established in patients under 18 years of age.
You should not use Linzess if you have a blockage in your intestines.
Linzess should not be given to a child younger than 6 years old. Linaclotide can cause severe dehydration in a child.
Take Linzess in the morning on an empty stomach, at least 30 minutes before your first meal. Do not crush, chew, break, or open a capsule. Swallow it whole.
Stop using Linzess and call your doctor at once if you have severe or ongoing diarrhea, severe stomach pain, or black, bloody, or tarry stools.
You should not use Linzess if you are allergic to linaclotide, or if you have:
a blockage in your intestines.
Linzess should not be given to a child younger than 6 years old. Linaclotide can cause severe dehydration in a child. Do not give this medicine to any child or teenager without the advice of a doctor.
It is not known whether Linzess will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether linaclotide passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Take Linzess exactly as prescribed by your doctor. Follow the directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take Linzess in the morning on an empty stomach, at least 30 minutes before your first meal.
Do not crush, chew, or break a Linzess capsule. Swallow the capsule whole.
If you cannot swallow the capsule whole, you may open the capsule and sprinkle the medicine into a spoonful of applesauce or bottled water. Swallow the mixture right away without chewing. Do not save it for later use.
Even if you have taken this medicine with applesauce, wait at least 30 minutes before eating a full meal.
If needed, medicine from the Linzess capsule may be given through a nasogastric (NG) or gastronomy tube.
Read all patient information, medication guides, and instruction sheets provided to you. Carefully follow instructions for mixing medicine from the capsule with applesauce or water, or giving the medicine through a feeding tube. Ask your doctor or pharmacist if you have any questions.
It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed. Call your doctor if your symptoms do not improve, or if they get worse while using Linzess.
Store at room temperature away from moisture and heat.
Keep this medicine out of the reach of children. Linzess can cause severe diarrhea and dehydration in a child who accidentally swallows this medicine. Seek emergency medical attention if this happens.
Keep the capsules in their original container, along with the packet of moisture-absorbing preservative that comes with this medicine. Keep the bottle tightly closed when not in use.
Usual Adult Dose for Irritable Bowel Syndrome:
290 mcg orally once a day
Comments:
-Take on an empty stomach, at least 30 minutes prior to the first meal of the day
-Swallow capsules whole; do not break apart or chew
Use: Irritable bowel syndrome with constipation
Usual Adult Dose for Constipation:
145 mcg orally once a day
Comments:
-Take on an empty stomach, at least 30 minutes prior to the first meal of the day
-Swallow capsules whole; do not break apart or chew
Use: Chronic idiopathic constipation
Skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Get emergency medical help if you have any signs of an allergic reaction to Linzess: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Linzess and call your doctor at once if you have:
severe or ongoing diarrhea;
diarrhea with dizziness or a light-headed feeling (like you might pass out);
signs of an electrolyte imbalance - increased thirst or urination, leg cramps, mood changes, confusion, feeling unsteady, irregular heartbeats, fluttering in your chest, muscle weakness or limp feeling;
severe stomach pain; or
black, bloody, or tarry stools.
Common Linzess side effects may include:
diarrhea;
stomach pain;
gas; or
bloating or full feeling in your stomach.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Other drugs may interact with linaclotide, including prescription, over-the-counter, vitamin, and herbal products. Tell your doctor about all medications you use, and those you start or stop using during your treatment.
Further informationRemember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Linzess (www.drugs.com/linzess.html).
Note: This document contains side effect information about linaclotide. Some of the dosage forms listed on this page may not apply to the brand name Linzess.
In SummaryCommon side effects of Linzess include: diarrhea. Other side effects include: flatulence. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to linaclotide: oral capsule
Oral route (Capsule)
Linaclotide is contraindicated in pediatric patients up less than 6 years of age; in nonclinical studies in neonatal mice, administration of a single, clinically relevant adult oral dose of linaclotide caused deaths due to dehydration. Avoid use of linaclotide in pediatric patients 6 to less than 18 years of age. The safety and efficacy of linaclotide has not been established in pediatric patients under 18 years of age.
Along with its needed effects, linaclotide (the active ingredient contained in Linzess) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking linaclotide:
More common
Less common
Rare
Some side effects of linaclotide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
For Healthcare Professionals
Applies to linaclotide: oral capsule
GastrointestinalVery common (10% or more): Diarrhea (up to 20%)
Common (1% to 10%): Abdominal pain, flatulence, abdominal distension, viral gastroenteritis, gastroesophageal reflux disease, vomiting, fecal incontinence, dyspepsia
Uncommon (0.1% to 1%): Defecation urgency
CardiovascularUncommon (0.1% to 1%): Orthostatic hypotension
DermatologicUncommon (0.1% to 1%): Urticaria
Frequency not reported: Rash
GeneralThe most commonly reported reasons for treatment discontinuation were diarrhea and abdominal pain.
GenitourinaryUncommon (0.1% to 1%): Hematochezia, melena, rectal hemorrhage
HypersensitivityUncommon (0.1% to 1%): Allergic reactions
MetabolicUncommon (0.1% to 1%): Dehydration, hypokalemia, decreased appetite
Rare (less than 0.1%): Decreased blood bicarbonate
Nervous systemCommon (1% to 10%): Headache, dizziness
OtherCommon (1% to 10%): Fatigue
RespiratoryCommon (1% to 10%): Upper respiratory tract infection, sinusitis
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Linzess (www.drugs.com/linzess.html).
August 5, 2020
December 16, 2020
March 1, 2021
February 15, 2021
March 1, 2021
February 1, 2021
Fact Checked
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