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Librax

Librax Prescription
Generic Name: chlordiazepoxide and clidinium (klor dye az e POX ide and kli DI nee um)
Brand Names: Librax
Librax is used to treat stomach ulcers and irritable bowel syndrome. Learn about side effects, interactions and indications.

Average Savings for chlordiazepoxide hcl/clid (generic): 93.42%
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Librax Drug Information:

Librax is a capsule containing a combination of chlordiazepoxide and clidinium. Chlordiazepoxide is a benzodiazepine that affects chemicals in the brain that may be unbalanced. Clidinium reduces stomach acid and decreases intestinal spasms. Librax is a medicine that may be effective in treating stomach ulcers, irritable bowel syndrome, or symptoms related to intestinal infection. Librax is given together with other medications to treat these conditions. The U.S. Food and Drug Administration has determined that Librax is "possibly" effective in treating these conditions. Learn more

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Librax Side Effects

Note: This document contains side effect information about chlordiazepoxide / clidinium. Some of the dosage forms listed on this page may not apply to the brand name Librax.

For the Consumer

Applies to chlordiazepoxide / clidinium: oral capsule

Warning

Oral route (Capsule)

Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation.

Along with its needed effects, chlordiazepoxide/clidinium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking chlordiazepoxide / clidinium:

Incidence not known

  • Abdominal or stomach pain
  • chills
  • clay-colored stools
  • confusion
  • cough or hoarseness
  • dark urine
  • difficulty with speaking
  • dizziness
  • drooling
  • drowsiness
  • fever with or without chills
  • general feeling of tiredness or weakness
  • headache
  • itching or rash
  • loss of appetite
  • loss of balance control
  • lower back or side pain
  • muscle trembling, jerking, or stiffness
  • nausea
  • painful or difficult urination
  • pale skin
  • restlessness
  • shakiness and unsteady walk
  • shuffling walk
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stiffness of the limbs
  • swelling
  • twisting movements of the body
  • uncontrolled movements, especially of the face, neck, and back
  • unpleasant breath odor
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual bruising or bleeding
  • unusual tiredness or weakness
  • vomiting of blood
  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking chlordiazepoxide / clidinium:

Symptoms of overdose

  • Blurred vision
  • change in consciousness
  • difficulty having a bowel movement (stool)
  • dry mouth
  • lack of coordination
  • loss of consciousness
  • sleepiness or unusual drowsiness

Some side effects of chlordiazepoxide / clidinium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Inability to have or keep an erection
  • increase or loss in sexual ability, desire, drive, or performance
  • increased or decreased interest in sexual intercourse
  • menstrual changes
  • skin blisters

For Healthcare Professionals

Applies to chlordiazepoxide / clidinium: oral capsule

General

The most common adverse events were sedation, dizziness, somnolence, ataxia, fatigue, and balance disorder.

Nervous system

Frequency not reported: Sedation, dizziness, somnolence, ataxia, balance disorder, drowsiness, syncope, extrapyramidal symptoms

The elderly and debilitated may be more susceptible to the side effects of chlordiazepoxide-clidinium. Drowsiness, ataxia, and confusion have occasionally been reported at the lower dosage ranges.

Gastrointestinal

Rare (less than 0.1%): Gastrointestinal disorder, constipation

Frequency not reported: Nausea, dry mouth

Hematologic

Rare (less than 0.1%): Bone marrow depression (e.g. thrombocytopenia, leukopenia, agranulocytosis, pancytopenia)

Hepatic

Frequency not reported: Jaundice, blood bilirubin increased, transaminases increase, hepatic dysfunction

Other

Common (1% to 10%): Fatigue

Frequency not reported: Blood alkaline phosphatase increased, asthenia, edema, changes in EEG patterns (low-voltage fast activity)

Ocular

Uncommon (0.1% to 1%): Lacrimation decreased, accommodation disorders

Rare (less than 0.1%): Visual impairment including diplopia

Frequency not reported: Blurring of vision

Genitourinary

Rare (less than 0.1%): Urinary retention, erectile dysfunction, menstrual disorder

Frequency not reported: Minor menstrual irregularities, urinary hesitancy

Dermatologic

Rare (less than 0.1%): Skin reaction (e.g. rash, pruritus)

Frequency not reported: Skin eruptions

Hypersensitivity

Frequency not reported: Hypersensitivity

Musculoskeletal

Frequency not reported: Muscular weakness

Metabolic

Uncommon (0.1% to 1%): Increased appetite

Psychiatric

Rare (less than 0.1%): Libido disorder

Frequency not reported: Amnesia, hallucinations, dependence, depression, restlessness, agitation, irritability, depressed level of consciousness, aggression, delusion, nightmares, psychotic disorder, abnormal behavior, emotional disturbances, paradoxical drug reaction (e.g. anxiety, sleep disorders, insomnia, suicide attempt, suicidal ideation), confusion

Respiratory

Frequency not reported: Respiratory depression, increased viscosity of bronchial secretion

Cardiovascular

Rare (less than 0.1%): Hypotension

Frequency not reported: Tachycardia, palpitations

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Librax (www.drugs.com/librax.html).