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Latuda Prescription
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Generic Name: lurasidone (loo RAS i done)
Brand Names: Latuda
Latuda information from Drugs.com, includes Latuda side effects, interactions and indications.
Generic Name: lurasidone (loo RAS i done)
Brand Names: Latuda
Latuda information from Drugs.com, includes Latuda side effects, interactions and indications.
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30 tablets of Latuda 40 mg
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Latuda Drug Information:

Latuda (lurasidone) is an antipsychotic medicine. It works by changing the effects of chemicals in the brain. Latuda is used to treat schizophrenia in adults and teenagers who are at least 13 years old. Latuda is also used to treat episodes of depression associated with bipolar disorder (bipolar depression) in adults and children who are at least 10 years old. Latuda is not approved for use in psychotic conditions related to dementia. Lurasidone may increase the risk of death in older adults with dementia-related conditions. Learn more

Latuda Medicare Coverage

Latuda Medicare Overview

Does Medicare cover Latuda?


100% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Latuda co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…


$312 – $1329

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Latuda

Here are some ways that may lower the cost of your latuda prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Latuda Side Effects

Note: This document contains side effect information about lurasidone. Some of the dosage forms listed on this page may not apply to the brand name Latuda.

In Summary

Common side effects of Latuda include: psychomotor impairment, akathisia, basal ganglia disease, bradykinesia, cogwheel rigidity, drowsiness, hypokinesia, muscle rigidity, nausea, parkinson's disease, sedated state, tremor, altered serum glucose, and drooling. Other side effects include: oculogyric crisis, trismus, agitation, anxiety, dystonia, torticollis, increased serum prolactin, and weight gain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to lurasidone: oral tablet


Oral route (Tablet)

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Lurasidone is not approved for the treatment of patients with dementia-related psychosis. An increased risk of suicidal thoughts and behavior was found in pediatric and young adult patients taking antidepressants. Monitor for clinical worsening and emergence of suicidal thoughts and behaviors.

Along with its needed effects, lurasidone (the active ingredient contained in Latuda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lurasidone:

More common

  • Absence of or decrease in body movement
  • difficulty with swallowing
  • drooling
  • inability to sit still
  • incremental or ratchet-like movement of the muscle
  • loss of balance control
  • mask-like face
  • muscle discomfort
  • muscle trembling, jerking, or stiffness
  • need to keep moving
  • restlessness
  • rigid or stiff muscles
  • shakiness in the legs, arms, hands, or feet
  • shuffling walk
  • slow movements
  • slow reflexes
  • slurred speech
  • stiffness of the arms and legs
  • tic-like (jerky) movements of the head, face, mouth, and neck
  • trembling or shaking of the hands or feet
  • twisting movements of the body
  • uncontrolled movements, especially of the face, neck, and back

Less common

  • Arm, back, or jaw pain
  • blurred vision
  • burning while urinating
  • changes in patterns and rhythms of speech
  • chest pain or discomfort
  • chills
  • cold sweats
  • confusion
  • difficult or painful urination
  • difficulty opening the mouth
  • difficulty with breathing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • fixed position of the eye
  • headache
  • high fever
  • inability to move the eyes
  • inability to speak
  • increased blinking or spasms of the eyelid
  • increased sweating
  • lockjaw
  • loss of bladder control
  • muscle spasm, especially of the neck and back
  • nervousness
  • pale skin
  • pounding in the ears
  • seizures
  • severe muscle stiffness
  • severe or sudden headache
  • slow or fast heartbeat
  • slurred speech
  • sticking out of the tongue
  • sweating
  • temporary blindness
  • tiredness
  • trouble with breathing, speaking, or swallowing
  • troubled breathing with exertion
  • uncontrolled twisting movements of the neck, trunk, arms, or legs
  • unusual bleeding or bruising
  • unusual facial expressions
  • unusual tiredness or weakness
  • unusually pale skin
  • weakness in the arm or leg on one side of the body, sudden and severe


  • Black, tarry stools
  • bloody urine
  • breast pain or swelling
  • cough
  • dark-colored urine
  • decreased frequency or amount of urine
  • fever
  • increased thirst
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • lower back or side pain
  • muscle cramp, pain, or stiffness
  • nausea
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the face, fingers, or lower legs
  • swollen glands
  • vomiting
  • weight gain

Incidence not known

  • Decreased urine output
  • hives or welts, itching, skin rash
  • loss of consciousness
  • redness of the skin
  • swelling of the throat or tongue
  • tightness in the chest

Some side effects of lurasidone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Anxiety
  • belching
  • drowsiness
  • dry mouth
  • heartburn
  • hyperventilation
  • indigestion
  • irritability
  • relaxed and calm feeling
  • sleepiness or unusual drowsiness
  • stomach discomfort, upset, or pain
  • trouble sleeping
  • unusually deep sleep
  • unusually long duration of sleep

Less common

  • Abnormal dreams
  • back pain
  • blurred vision
  • burning feeling in the chest or stomach
  • decreased appetite
  • diarrhea
  • feeling of constant movement of self or surroundings
  • indigestion
  • sensation of spinning
  • sweating
  • tenderness in the stomach area
  • watering of mouth and drooling


  • Decreased interest in sexual intercourse
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance
  • unexpected or excess milk flow from the breasts

For Healthcare Professionals

Applies to lurasidone: oral tablet


The most commonly reported adverse events included somnolence, akathisia, extrapyramidal symptoms, and nausea.


Common (1% to 10%): Decreased appetite, increased appetite, increased weight

Uncommon (0.1% to 1%): Hyponatremia, increase in blood sugar levels/blood glucose increased

In uncontrolled, long-term schizophrenia trials, this drug was associated with a mean increase in glucose from baseline of 1.8 mg/dL at 24 weeks, 0.8 mg/dL at 36 weeks, and 2.3 mg/dL at 52 weeks. Similar results were observed in bipolar depression studies. The proportion of patients with a 7% or greater increase in body weight was 4.8% (compared with 3.3% for placebo). Pooled data from short-term trials showed a mean weight gain of 0.43 kg in treated patients (compared with -0.2 kg in placebo).


Very common (10% or more): Nausea (up to 17.4%), dyspepsia (up to 11%)

Common (1% to 10%): Abdominal pain, diarrhea, dry mouth, salivary hypersecretion, stomach discomfort, upper abdominal pain, vomiting

Uncommon (0.1% to 1%): Dysphagia, flatulence, gastritis

Frequency not reported: Difficulty swallowing, tongue protrusion, tongue spasm, tongue swelling

Nervous system

Akathisia and extrapyramidal symptoms were dose-related.

Very common (10% or more): Somnolence (up to 26%), akathisia (up to 22%), extrapyramidal disorder/symptoms (up to 22%), parkinsonism (up to 17%)

Common (1% to 10%): Dizziness, dyskinesia, dystonia/acute dystonia, tardive dyskinesia

Uncommon (0.1% to 1%): Cerebrovascular accident/adverse reactions, dysarthria, gait disturbance, lethargy, syncope, vertigo

Rare (less than 0.1%): Neuroleptic malignant syndrome, seizure

Frequency not reported: Abnormal glabellar reflex, bradykinesia, cogwheel rigidity, convulsion, drooling, hyperkinesia, hypersomnia, hypersomnolence, hypokinesia, motor impairment, oromandibular dystonia, sedation, stroke, tremor


Very common (10% or more): Insomnia (up to 11%)

Common (1% to 10%): Abnormal dreams, agitation, anxiety, psychomotor hyperactivity, restlessness

Uncommon (0.1% to 1%): Activation of mania/hypomania, catatonia, nightmare, panic attack, sleep disorder

Rare (less than 0.1%): Suicidal behavior/ideation

Frequency not reported: Cognitive impairment, psychomotor retardation


Uncommon (0.1% to 1%): Anemia

Rare (less than 0.1%): Eosinophilia

Frequency not reported: Agranulocytosis, leukopenia, neutropenia


Common (1% to 10%): Hypertension, tachycardia

Uncommon (0.1% to 1%): Angina pectoris, atrioventricular (AV) block first degree, bradycardia, hot flush, hypotension, increased blood pressure, orthostatic hypotension

Frequency not reported: Deep vein thrombosis, venous thromboembolism


Common (1% to 10%): Back pain, increased blood creatinine phosphokinase, musculoskeletal stiffness

Uncommon (0.1% to 1%): Joint stiffness, myalgia, neck pain

Rare (less than 0.1%): Rhabdomyolysis

Frequency not reported: Muscle rigidity, muscle spasms, neck muscle spasm, torticollis, trismus


Common (1% to 10%): Rash, pruritus

Uncommon (0.1% to 1%): Hyperhidrosis

Frequency not reported: , Stevens-Johnson syndrome, urticaria

Postmarketing reports: Bullous dermatitis, maculopapular rash, pustular rash, severe cutaneous reactions, skin eruption, skin exfoliation


Common (1% to 10%): Urinary tract infection

Uncommon (0.1% to 1%): Amenorrhea, dysmenorrhea, dysuria, erectile dysfunction

Rare (less than 0.1%): Breast enlargement, breast pain, galactorrhea


Common (1% to 10%): Elevated serum creatinine/increased creatinine phosphokinase

Rare (less than 0.1%): Renal failure


Uncommon (0.1% to 1%): Elevated prolactin levels/blood prolactin increased

Frequency not reported: Hyperprolactinemia


Uncommon (0.1% to 1%): Alanine aminotransferase increased


Common (1% to 10%): Hypersensitivity

Rare (less than 0.1%): Angioedema

Frequency not reported: Allergic rhinitis


Very common (10% or more): Viral infection (up to 11%)

Common (1% to 10%): Influenza


Common (1% to 10%): Blurred vision

Frequency not reported: Oculogyric crisis


Common (1% to 10%): Fatigue

Rare (less than 0.1%): Sudden death

Frequency not reported: Body temperature dysregulation, falls, neonatal drug withdrawal syndrome


Common (1% to 10%): Nasopharyngitis, oropharyngeal pain, rhinitis

Frequency not reported: Difficulty breathing, nasal congestion, rhinorrhea, pulmonary embolism, throat tightness, upper respiratory tract infection

Postmarketing reports: Dyspnea, throat swelling

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

Source: Drugs.com Latuda (www.drugs.com/latuda.html).