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Commonly reported side effects of lanthanum carbonate include: dialysis graft complication, nausea, and vomiting. Other side effects include: dialysis graft occlusion, and abdominal pain. See below for a comprehensive list of adverse effects.For the Consumer
Applies to lanthanum carbonate: oral powder, oral tablet chewable
Along with its needed effects, lanthanum carbonate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lanthanum carbonate:
Incidence not known
Get emergency help immediately if any of the following symptoms of overdose occur while taking lanthanum carbonate:
Symptoms of overdose
Some side effects of lanthanum carbonate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
For Healthcare Professionals
Applies to lanthanum carbonate: oral powder for reconstitution, oral tablet chewableGeneral
The most common adverse reactions included nausea, vomiting, and abdominal pain.Gastrointestinal
Nausea, diarrhea, and vomiting occurred more frequently among patients taking the oral powder formulation than those receiving the chewable tablets (18% versus 7%).
Very common (10% or more): Nausea (up to 37%), vomiting (up to 27%), diarrhea (up to 24%), abdominal pain (up to 17%), constipation (up to 15%)
Common (1% to 10%): Dyspepsia, flatulence
Uncommon (0.1% to 1%): Gastroenteritis, eructation, indigestion, irritable bowel syndrome, dry mouth, stomatitis, loose stools, esophagitis, tooth disorder
Postmarketing reports: Tooth injury chewing the tablet, intestinal perforation, intestinal obstruction, ileus, subileusMetabolic
Common (1% to 10%): Hypocalcemia
Uncommon (0.1% to 1%): Hypercalcemia, hyperglycemia, hyperphosphatemia, hypophosphatemia, anorexia, appetite increased, thirstRespiratory
Common (1% to 10%): Bronchitis, rhinitis
Uncommon (0.1% to 1%): LaryngitisEndocrine
Uncommon (0.1% to 1%): Hyperparathyroidism
Serum parathyroid concentrations may fluctuate depending on a patient's serum calcium, phosphate and vitamin D status. This drug has not been shown to have any direct effects on PTH secretion.Hypersensitivity
Postmarketing reports: Allergic skin reactions (skin rashes, urticaria, and pruritus)Musculoskeletal
The effects of this drug on the bones of patients undergoing dialysis have been evaluated in studies of up to 4.5 years duration. Compared with standard treatments including calcium carbonate, no differences in adverse effects on the musculoskeletal system, including fractures, were observed.
Uncommon (0.1% to 1%): Arthralgia, myalgia, osteoporosisDermatologic
Uncommon (0.1% to 1%): Alopecia, increased sweatingOther
Uncommon (0.1% to 1%): Vertigo, asthenia, fatigue, malaiseCardiovascular
Uncommon (0.1% to 1%): Chest pain, peripheral edemaHematologic
Uncommon (0.1% to 1%): EosinophiliaNervous system
Very common (10% or more): Headache (up to 22%)
Uncommon (0.1% to 1%): Dizziness, taste alterationRenal
Very common (10% or more): Dialysis graft occlusion (up to 25%)
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