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Applies to lansoprazole: oral capsule delayed release, oral powder for suspension, oral tablet disintegrating delayed release
Along with its needed effects, lansoprazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lansoprazole:
Incidence not known
Some side effects of lansoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Applies to lansoprazole: compounding powder, intravenous powder for injection, oral delayed release capsule, oral granule for reconstitution, oral suspension, oral tablet disintegrating
The most commonly reported side effects include headache, dizziness, fatigue, and malaise.
Pseudomembranous colitis may occur with triple therapy for the eradication of H. pylori.
The majority of patients with severe/protracted cases of diarrhea who discontinued treatment had symptom resolution.
Common (1% to 10%): Abdominal pain, benign fundic gland polyps, constipation, diarrhea, dry mouth, flatulence, nausea, stomachache, vomiting
Rare (0.01% to 0.1%): Candidiasis of the esophagus, glossitis, macroscopic/microscopic colitis, pancreatitis
Very rare (less than 0.01%): Colitis, stomatitis
Frequency not reported: Abdomen enlarged, abnormal stools, bezoar, cardiospasm, collagenous colitis, duodenitis, dyspepsia, dysphagia, enteritis, epigastric discomfort, eructation, esophageal disorder, esophageal stenosis, esophageal ulcer, esophagitis, fecal discoloration, gastric nodules/fundic gland polyps, gastritis, gastroenteritis, gastrointestinal anomaly/disorder/hemorrhage, gastrointestinal moniliasis, gum hemorrhage, halitosis, hematemesis, hiatal hernia, impaired gastric emptying, increased salivation, melena, mouth ulceration, positive fecal occult blood, protracted diarrhea, pseudomembranous colitis/Clostridium difficile-associated diarrhea, rectal disorder, rectal hemorrhage, sore mouth, tenesmus, tongue disorder, ulcerative colitis, ulcerative stomatitis
Skin rashes, urticaria, and pruritus generally resolved upon discontinuation of therapy.
Common (1% to 10%): Itching, pruritus, rash, urticaria
Rare (0.01% to 0.1%): Bullous rashes, cutaneous lupus erythematosus, erythema multiforme, erythematous rashes, hair loss, hair thinning, hyperhidrosis, petechia, photosensitivity, purpura, serious dermatological reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis
Frequency not reported: Acne, alopecia, contact dermatitis, dry skin, fixed eruption, hair disorder, maculopapular rash, nail disorder, subacute cutaneous lupus erythematosus, skin disorder, sweating
Postmarketing reports: Fatal toxic epidermal necrolysis
Common (1% to 10%): Dizziness, headache, taste perversion
Rare (0.01% to 0.1%): Paresthesia, somnolence, taste disturbance, tremor, vertigo
Frequency not reported: Amnesia, cerebrovascular accident/cerebral infarction, convulsion, dementia, hemiplegia, hyperkinesia, hypertonia, hypesthesia, migraine, parosmia, syncope, taste loss
Postmarketing reports: Speech disorder
Common (1% to 10%): Increased liver enzyme levels (alkaline phosphatase, ALT, AST, GGT)
Rare (0.01% to 0.1%): Hepatitis, jaundice
Frequency not reported: Bilirubinemia, cholelithiasis, increased alkaline phosphatase, increased ALT, increased AST, increased GGT
Postmarketing reports: Hepatotoxicity
Common (1% to 10%): Fatigue
Rare (0.01% to 0.1%): Fever
Frequency not reported: Additional isolated laboratory abnormalities, asthenia, chills, deafness, ear disorder, malaise, otitis media, pain, tinnitus
A definitive relationship between use of this drug and interstitial pneumonia has not been established.
Common (1% to 10%): Dry throat
Frequency not reported: Asthma, bronchitis, cough increased, dyspnea, epistaxis, hemoptysis, hiccup, hoarseness, interstitial pneumonia, lung fibrosis, pharyngitis, pleural disorder, pneumonia, respiratory disorder, rhinitis, sinusitis, sore throat, stridor, upper respiratory tract infection, upper respiratory tract inflammation, wheezing
Uncommon (0.1% to 1%): Arthralgia, fracture of the hip/wrist/spine, myalgia
Frequency not reported: Arthritis, back pain, bone disorder, bone fracture, joint disorder, leg cramps, myasthenia, musculoskeletal pain, neck pain, neck rigidity, synovitis, systemic lupus erythematosus
Postmarketing reports: Myositis
Uncommon (0.1% to 1%): Eosinophilia, leukopenia, thrombocytopenia
Rare (0.01% to 0.1%): Agranulocytosis, anemia, hematological effects, neutropenia, pancytopenia
Frequency not reported: Abnormal albumin globulin (AG) ratio, abnormal platelets, abnormal RBC, abnormal WBC, bruising, contusion, decreased platelets, decreased WBC, hemoglobin decreased, hemolysis, increased globulins, increased platelets, increased WBC, lymphadenopathy
Postmarketing reports: Aplastic anemia, hemolytic anemia, thrombotic thrombocytopenic purpura
Rare (0.01% to 0.1%): Confusion, hallucination, insomnia, restlessness
Frequency not reported: Abnormal dreams, abnormal thinking, agitation, anxiety, apathy, depersonalization, emotional lability, hostility aggravated, libido increased/decreased, nervousness, neurosis, sleep disorder, visual hallucinations
Uncommon (0.1% to 1%): Edema
Frequency not reported: Angina, arrhythmia, bradycardia, chest pain (not otherwise specified [NOS]), hypertension, hypotension, myocardial infarction, palpitations, peripheral edema, shock/circulatory failure, tachycardia, vasodilation
Rare (0.01% to 0.1%): Anorexia, hypomagnesemia
Very rare (less than 0.01%): Hyponatremia, increased cholesterol/triglyceride levels
Frequency not reported: Avitaminosis, blood potassium increased, cyanocobalamin (vitamin B12) deficiency), decreased cholesterol, dehydration, diabetes mellitus, gout, hunger, hyperglycemia, hyperlipemia, hypoglycemia, increased appetite, increased lactate dehydrogenase (LDH), increased/decreased electrolytes, thirst, weight gain/loss
A definitive relationship between use of this drug and hyponatremia has not been established.
Rare (0.01% to 0.1%): Erectile dysfunction, impotence
Frequency not reported: Abnormal menses, albuminuria, breast enlargement, breast pain, breast tenderness, crystal urine present, dysmenorrhea, dysuria, hematuria, leukorrhea, menorrhagia, menstrual disorder, pelvic pain, penis disorder, polyuria, testis disorder, urethral pain, urinary frequency, urinary retention, urinary tract infection, urinary urgency, urination impaired, vaginitis
Rare (0.01% to 0.1%): Angioedema
Very rare (less than 0.01%): Anaphylactic reaction, anaphylactic shock
Frequency not reported: Allergic reaction
Postmarketing reports: Anaphylactoid reactions
Rare (0.01% to 0.1%): Visual disturbances
Frequency not reported: Abnormal vision, amblyopia, blepharitis, blurred vision, cataract, conjunctivitis, diplopia, dry eyes, eye disorder, eye pain, glaucoma, photophobia, ptosis, retinal degeneration/disorder, visual field defect
Some cases of interstitial nephritis resulted in renal failure.
Rare (0.01% to 0.1%): Interstitial nephritis
Frequency not reported: Acute interstitial nephritis, blood urea increased, kidney calculus, kidney pain, glycosuria, increased creatinine, renal dysfunction, renal failure
Rare (0.01% to 0.1%): Gynecomastia
Frequency not reported: Goiter, hypothyroidism, increased gastrin levels, increased glucocorticoids
Frequency not reported: Carcinoma, laryngeal neoplasia, metaplasia, skin carcinoma
Frequency not reported: Candidiasis, flu syndrome, infection NOS
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May 12, 2020
May 12, 2020
May 12, 2020
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May 11, 2020