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Klonopin (clonazepam) is a benzodiazepine. Clonazepam affects chemicals in the brain that may be unbalanced. Clonazepam is also a seizure medicine, also called an anti-epileptic drug.
Klonopin is used to treat certain seizure disorders (including absence seizures or Lennox-Gastaut syndrome) in adults and children.
Klonopin is also used to treat panic disorder (including agoraphobia) in adults.
Klonopin may also be used for purposes not listed in this medication guide.
You should not use Klonopin if you have narrow-angle glaucoma, severe liver disease, or if you are allergic to Valium or a similar medicine.
Call your doctor if you have any new or worsening symptoms of depression, unusual changes in behavior, or thoughts about suicide or hurting yourself.
Do not drink alcohol while taking this medicine. Clonazepam may be habit-forming. Never share Klonopin with another person. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Using Klonopin with opiate medications can result in sedation, respiratory depression, coma, and death.
You should not take Klonopin if you have:
narrow-angle glaucoma;
severe liver disease; or
a history of allergic reaction to any benzodiazepine, such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), chlordiazepoxide, flurazepam, and others.
To make sure Klonopin is safe for you, tell your doctor if you have ever had:
kidney or liver disease;
glaucoma;
asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);
depression or suicidal thoughts or behavior;
mental illness, psychosis, or addiction to drugs or alcohol; or
use other medications that cause sedation; or
if you use a narcotic (opioid) medication.
Some people have thoughts about suicide when taking Klonopin. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Follow your doctor's instructions about taking seizure medication if you are pregnant. Do not start or stop taking this medicine without your doctor's advice, and tell your doctor right away if you become pregnant. Clonazepam may cause harm to an unborn baby, and may cause breathing or feeding problems in a newborn. But having seizures during pregnancy could harm both mother and baby.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of clonazepam on the baby.
Clonazepam can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding.
Do not give this medicine to a child without medical advice. Klonopin is not approved to treat panic disorder in anyone younger than 18 years old.
Take Klonopin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Klonopin may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
Klonopin should be used for only a short time. Do not take this medication for longer than 9 weeks without your doctor's advice.
Swallow the tablet whole, with a full glass of water.
Do not stop using Klonopin suddenly or you could have unpleasant withdrawal symptoms, including a seizure (convulsions). Ask your doctor how to safely stop using this medicine.
Call your doctor if this medicine seems to stop working as well in treating your seizures or anxiety symptoms.
Seizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.
Store at room temperature away from moisture, heat, and light.
Keep track of the amount of medicine used from each new bottle. Klonopin is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.
Avoid drinking alcohol. Dangerous side effects could occur.
Klonopin may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Get emergency medical help if you have signs of an allergic reaction to Klonopin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
new or worsening seizures;
severe drowsiness;
unusual changes in mood or behavior;
confusion, aggression, hallucinations;
thoughts of suicide or hurting yourself;
weak or shallow breathing;
pounding heartbeats or fluttering in your chest; or
unusual or involuntary eye movements.
The sedative effects of clonazepam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking clonazepam.
Common Klonopin side effects may include:
feeling tired or depressed;
drowsiness, dizziness;
memory problems; or
problems with balance or coordination.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, an opioid medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Other drugs may interact with clonazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Klonopin only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Klonopin (www.drugs.com/klonopin.html).
Note: This document contains side effect information about clonazepam. Some of the dosage forms listed on this page may not apply to the brand name Klonopin.
Common side effects of Klonopin include: drowsiness. Other side effects include: upper respiratory tract infection, ataxia, depression, and dizziness. See below for a comprehensive list of adverse effects.
Applies to clonazepam: oral tablet, oral tablet disintegrating
Oral route (Tablet)
Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation.
Along with its needed effects, clonazepam (the active ingredient contained in Klonopin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking clonazepam:
More common
Less common
Rare
Incidence not known
Some side effects of clonazepam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Rare
Incidence not known
Applies to clonazepam: oral tablet, oral tablet disintegrating
The most commonly reported side effects included drowsiness, somnolence, ataxia, and behavior problems.
Reversible ataxia, dysarthria, anterograde amnesia, and nystagmus may occur, especially in long-term treatment and/or at high doses.
Transient somnolence, dizziness, ataxia, lightheadedness, muscular hypotonia, and/or coordination disturbances may occur, and usually disappear spontaneously when treatment is continued or upon dose reductions.
Very common (10% or more): Drowsiness (up to 50%), somnolence (up to 50%), ataxia (up to 30%), dizziness (up to 12%)
Common (1% to 10%): Abnormal coordination, dysarthria, intellectual ability reduced, memory disturbance, nystagmus
Rare (0.01% to 0.1%): Convulsions, headache
Very rare (less than 0.01%): Generalized fits, lightheadedness
Frequency not reported: Activation of new types of seizures, amnestic effects, anterograde amnesia/amnesia, aphonia, attention lack, coma, coordination disturbances, decreased movement and gait coordination, disturbance in attention, dysdiadochokinesis/inability to perform rapid, alternating movements, dysphagia, epileptic seizures, extremity numbness and tingling, forgetfulness, head fullness, hemiparesis, hyperactivity, hyperphagia, hypersensitivity to light/noise/physical contact, hypertonia, hypoesthesia, impaired concentration/poor concentration, lethargy, migraine, motion sickness, muscular hypotonia, paresis, paresthesia, seizures, speech slowing/slurring, taste loss, tremor, vertigo, visual field defect
Postmarketing reports: Choreiform movements, hypotonia, preexisting brain damage
Reversible inappropriate behavior may occur, especially in long-term treatment and/or at high doses.
Very common (10% or more): Behavior problems (up to 25%)
Common (1% to 10%): Confusion/confusional state, decreased libido, depression, emotional lability, nervousness
Rare (0.01% to 0.1%): Decrease in sexual drive, loss of libido
Frequency not reported: Aggressive behavior/aggressive reaction/aggression/aggressiveness, agitation, anger, anxiety, apathy, depersonalization, derealization, disorientation, drug withdrawal symptoms, dysphoria, excessive dreaming, excitability/excitement, extreme anxiety, feeling mad, hallucinations, hostility, hysteria, illusion, inappropriate behavior, increased libido, insomnia, irritability, nightmares, organic disinhibition, physical dependence, psychological dependence, psychosis, psychotic disorders, restlessness, sleep disorder, sleep disturbance, suicidal attempt, suicide ideation, tension, vivid dreams, worsening/emergence of clinical depression
Postmarketing reports: Abnormal dreams, change in libido, dependence, encopresis
Very common (10% or more): Upper respiratory tract infection (up to 10%)
Common (1% to 10%): Bronchitis, coughing, pharyngitis, rhinitis, sinusitis
Rare (0.01% to 0.1%): Respiratory depression
Frequency not reported: Asthmatic attach, bronchial hypersecretion/hypersecretion in upper respiratory passages, chest congestion, dyspnea, excessive sneezing, hoarseness, mucus obstruction of the nasopharynx, nosebleed, pneumonia, rhinorrhea, shortness of breath, yawning
Postmarketing reports: Airway obstruction, pharyngeal edema
Common (1% to 10%): Colpitis, dysmenorrhea, ejaculation delayed, impotence, micturition frequency, urinary tract infection
Rare (0.01% to 0.1%): Erectile dysfunction, urinary incontinence
Frequency not reported: Bladder dysfunction, breast pain, dysuria, ejaculation decreased, enuresis/feeling of enuresis, menstrual irregularity, nocturia, pain pelvic, polyuria, urinary retention, urinary tract bleeding, urine discoloration
Transient fatigue, lassitude, slowed reaction, and/or tiredness may occur, and usually disappear spontaneously when treatment is continued or upon dose reductions.
Common (1% to 10%): Fatigue, lassitude, tiredness
Frequency not reported: Accident, drunkenness, earache, fever, herpes simplex infection, hyperacusis, injury, malaise, otitis, pain, paradoxical reaction, reaction slowed/decreased, shivering, thirst, wound
Postmarketing reports: Falls, general deterioration
Common (1% to 10%): Abdominal pain, constipation
Rare (0.01% to 0.1%): Epigastric discomfort/symptoms, gastrointestinal symptoms, nausea
Frequency not reported: Abdominal discomfort, bowel movements frequent, coated tongue, dyspepsia, flatulence, gastrointestinal inflammation, hemorrhoids, pyrosis, salivary hypersecretion/saliva increased/hypersalivation, stomach upset, tongue thick, toothache, tooth disorder, vomiting
Postmarketing reports: Diarrhea, dry mouth, gastritis, sore gums
Common (1% to 10%): Muscle weakness, myalgia
Frequency not reported: Ankle pain, arthralgia, back pain, foot pain, fracture traumatic, knee pain, knee swelling, jaw pain, leg cramps, leg pain, lumbago, muscle cramps, muscle pain, nape pain, shoulder pain, sprains, strains, tendinitis, twitching
Postmarketing reports: Fractures
Common (1% to 10%): Allergic reaction
Rare (0.01% to 0.1%): Angioedema
Frequency not reported: Anaphylaxis
Common (1% to 10%): Blurred vision
Frequency not reported: Diplopia/double vision, eye irritation, eye twitching, periorbital edema, stye, visual disturbance, xerophthalmia
Postmarketing reports: Abnormal eye movements, "glassy-eyed" appearance
Reversible vision disorders (e.g., diplopia) may occur, especially in long-term treatment and/or at high doses.
Common (1% to 10%): Appetite decreased
Frequency not reported: Anorexia, dehydration, gout, hunger abnormal, increased appetite, weight gain, weight loss
Common (1% to 10%): Influenza
Frequency not reported: Infection mycotic, infection streptococcal, infection viral, moniliasis
Rare (0.01% to 0.1%): Pigmentation changes, pruritus, rash/skin rash, transient hair loss, urticaria
Frequency not reported: Abrasions, acne flare, alopecia/transient hair loss, bleeding dermal, burning skin, cellulitis, dermatitis contact, facial edema, hair loss, hirsutism, pustular reaction, skin disorder, sweating, xeroderma
Postmarketing reports: Angioneurotic edema, pigmentation disorder
Rare (0.01% to 0.1%): Decreased platelet count
Frequency not reported: Anemia, blood dyscrasias, eosinophilia, infectious mononucleosis, leukopenia, lymphadenopathy
Postmarketing reports: Thrombocytopenia
Frequency not reported: Ankle edema, chest pain, edema, flushing, foot edema, palpitations, postural hypotension, tachycardia, thrombophlebitis leg
Postmarketing reports: Cardiac arrest, cardiac failure, thrombophlebitis, thrombosis
Tachycardia occurred after IV administration.
Frequency not reported: Abnormal liver function tests, hepatomegaly
Postmarketing reports: Transient elevations of serum transaminases and alkaline phosphatase
Frequency not reported: Incomplete precocious puberty/premature secondary sex characteristics
Frequency not reported: Localized inflammation
Frequency not reported: Cystitis
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Klonopin (www.drugs.com/klonopin.html).
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