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Kinevac

Generic Name: sincalide (SIN ka lide)
Brand Name: Kinevac
Physician reviewed Kinevac patient information - includes Kinevac description, dosage and directions.
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Drug Information:
Kinevac is used to help diagnose disorders of the gallbladder or pancreas. Kinevac is also used to speed up digestion of barium, a contrast agent, given in preparation for x-ray examination of the intestines. Kinevac may also be used for purposes not listed in this medication guide. You should not receive Kinevac if you have a blockage in your intestines. Tell your doctor if you are pregnant. Receiving Kinevac during pregnancy may result in a miscarriage or premature labor. You should not be treated with Kinevac if you are allergic to it, or if you have a blockage in your intestines. Learn more

Kinevac Side Effects

Kinevac Side Effects

Note: This document contains side effect information about sincalide. Some of the dosage forms listed on this page may not apply to the brand name Kinevac.

For the Consumer

Applies to sincalide: intravenous powder for solution

Along with its needed effects, sincalide (the active ingredient contained in Kinevac) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking sincalide:

Less common or rare

  • Dizziness, fainting, or lightheadedness
  • increase in blood pressure
  • shortness of breath
  • skin rash

Some side effects of sincalide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Abdominal or stomach pain, cramps, or discomfort
  • nausea

Less common or rare

  • Diarrhea
  • dizziness
  • flushing or redness of skin
  • headache
  • increased sweating
  • numbness
  • sneezing
  • urge to have bowel movement
  • vomiting

For Healthcare Professionals

Applies to sincalide: injectable powder for injection, intravenous powder for injection

Gastrointestinal

Gastrointestinal side effects have included abdominal discomfort or pain and nausea. Rapid IV injection of 0.04 mcg sincalide (the active ingredient contained in Kinevac) per kg would be expected to cause transient abdominal cramping. These side effects are usually manifestations of the physiologic action of the drug, including delayed gastric emptying and increased intestinal motility. These side effects occurred in approximately 20% of patients but they are not to be construed as necessarily indicating an abnormality of the biliary tract unless there is other clinical or radiologic evidence of disease.

General

Reactions to sincalide (the active ingredient contained in Kinevac) are usually mild and of short duration. Adverse reactions including vomiting, flushing, sweating, rash, hypotension, hypertension, shortness of breath, urge to defecate, headache, diarrhea, sneezing, and numbness were less than 1%. Dizziness was reported in approximately 2% of patients. These manifestations are usually attenuated by a slower injection rate.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Kinevac (www.drugs.com/mtm/kinevac.html).