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Jardiance Prescription
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Generic Name: empagliflozin (EM pa gli FLOE zin)
Brand Names: Jardiance
Jardiance (empagliflozin) is used to treat type 2 diabetes. Includes Jardiance side effects, interactions and indications.
Generic Name: empagliflozin (EM pa gli FLOE zin)
Brand Names: Jardiance
Jardiance (empagliflozin) is used to treat type 2 diabetes. Includes Jardiance side effects, interactions and indications.
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30 tablets of Jardiance 40 mg
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Offers Claimed: 68

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Jardiance Drug Information:

Jardiance (empagliflozin) is an oral Diabetes medicine that helps control blood sugar levels. Empagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Jardiance is used together with diet and exercise to improve blood sugar control in adults with type 2 Diabetes mellitus. Jardiance is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 Diabetes who also have heart disease. Jardiance is not for treating type 1 Diabetes. Learn more

Jardiance Medicare Coverage

Jardiance Medicare Overview

Does Medicare cover Jardiance?


96% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Jardiance co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…


$42 – $612

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Jardiance

Here are some ways that may lower the cost of your jardiance prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Jardiance Side Effects

Note: This document contains side effect information about empagliflozin. Some of the dosage forms listed on this page may not apply to the brand name Jardiance.

In Summary

Common side effects of Jardiance include: urinary tract infection. Other side effects include: vulvovaginal candidiasis, cervicitis, genital candidiasis, genitourinary infection, vaginal infection, vulvitis, and vulvovaginitis. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to empagliflozin: oral tablet

Along with its needed effects, empagliflozin (the active ingredient contained in Jardiance) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking empagliflozin:

More common

  • Bladder pain
  • bloody or cloudy urine
  • change in the color, amount, or odor of vaginal discharge
  • difficult, burning, or painful urination
  • frequent urge to urinate
  • itching, stinging, or redness of the vaginal area
  • lower back or side pain
  • pain during sexual intercourse

Less common

  • Discharge with a strong odor from the penis
  • increased volume of pale, dilute urine
  • redness, itching, swelling, or pain around the penis
  • waking to urinate at night


  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • confusion
  • decreased urination
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast heartbeat
  • headache
  • increased hunger
  • nausea
  • nightmares
  • rapid breathing
  • seizures
  • shakiness
  • slurred speech
  • sweating
  • unusual tiredness or weakness

Incidence not known

  • Dry mouth
  • fever
  • flushed, dry skin
  • fruit-like breath odor
  • increased thirst
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • loss of consciousness
  • stomach pain
  • troubled breathing
  • unexplained weight loss
  • vomiting
  • weight gain

Some side effects of empagliflozin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Body aches or pain
  • cough
  • loss of voice
  • muscle pain or stiffness
  • nasal congestion

For Healthcare Professionals

Applies to empagliflozin: oral tablet


The most common reported side effects included urinary tract infections and female genital mycotic infections.


Frequency of hypoglycemia depended on the type of background therapy used. In combination with metformin and sulfonylurea, hypoglycemia was reported in 16.1% of patients taking the 10 mg dose and 11.5% in patients taking the 25 mg dose. In combination with insulin, hypoglycemia was reported in 22.5% of patients taking the 10 mg dose and 29.7% in patients taking the 25 mg dose.

Twenty reports of acidosis have been identified in the US Food and Drug Administration Adverse Event Reporting System (FAERS) database during the period March 2013 through 06 June 2014. All patients required emergency room treatment or hospitalization. These cases were not typical of ketoacidosis or diabetic ketoacidosis (DKA) in that they occurred in patients with type 2 diabetes and their blood sugar levels were only slightly increased. Some factors identified as potentially triggering the acidosis included major illness, reduced food and fluid intake, and reduced insulin dose.

Common (1% to 10%): Increased low-density lipoprotein cholesterol

Frequency not reported: Hypoglycemia

Postmarketing reports: Diabetic ketoacidosis, ketoacidosis


Common (1% to 10%): Increased urination

Uncommon (0.1% to 1%): Dysuria

Frequency not reported: Increased serum creatinine, decreased eGFR

Postmarketing reports: Acute kidney injury, urosepsis, pyelonephritis


In the 5 years (2013 to 2018) since SGLT2 inhibitor approval, 12 cases of Fournier's gangrene have been reported. Reports were almost equal in men and women (men=7; women=5), ages ranged from 38 to 78 years, and the average time to onset after starting an SGLT2 inhibitor was 9.2 months (range 7 days to 25 months). All SGLT2 inhibitor drugs except ertugliflozin were included in the reports. Ertugliflozin being the most recently approved agent, is expected to have the same risk, but insufficient patient use to assess risk. All patients were hospitalized, all required surgery, all required surgical debridement, 5 required more than 1 surgery and 1 required skin grafting. Four cases were complicated by diabetic ketoacidosis, acute kidney injury, and septic shock, leading to prolonged hospitalization, and death in 1 case. In the general population, Fournier's gangrene occurs in about 1.6 out of 100,000 males annually, with the highest incidence in men 50 to 79 years. Since diabetes is a risk factor for Fournier's gangrene, a review of the FAERS database for the last 34 years was done and only 6 cases (all males, median age 57 years) were found with several other classes of antidiabetic drugs. Findings with SGLT2 inhibitors appear to show an association over a shorter time frame and involve both males and females.

Common (1% to 10%): Female and male genital mycotic infections, urinary tract infection

Uncommon (0.1% to 1%): Phimosis

Postmarketing reports: Urosepsis, pyelonephritis, Fournier's gangrene


Volume depletion included decreased ambulatory blood pressure, decreased systolic blood pressure, dehydration, hypotension, hypovolemia, orthostatic hypotension, and syncope.

Uncommon (0.1% to 1%): Volume depletion


Postmarketing reports: Angioedema


Common (1% to 10%): Pruritus

Postmarketing reports: Skin reactions including rash, urticaria


Common (1% to 10%): Nausea


Common (1% to 10%): Increased hematocrit


Common (1% to 10%): Arthralgia


Common (1% to 10%): Upper respiratory tract infection

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Jardiance (www.drugs.com/jardiance.html).

What pharmacies accept this discount program?

Rite Aid, Wal-Mart, Walgreens, CVS, Duene Reade, Target, K-mart, and all national and regional chains accept the patient assistance program. Additional information on our pharmacy coverage is on your coupon.

What if you didn’t find your Pharmacy Names above or generally go to independent pharmacies?

Not to worry, our savings card is accepted at national, regional, and independent pharmacies across the U.S. Our goal is to reduce your medication cost with this free Jardiance coupon. When the Jardiance coupon is in he pharmacy system, it can apply to all prescription medications. Additional information is on your coupon.

What if the Pharmacist refuses to take the coupon?

If they are in the participating network and in the U.S., they legally have to accept and process the card for your prescription medication. We work with drug manufacturers and pharmacies to give you this discount price. If the pharmacist needs help in processing the card, have them call the support phone number or email us directly for additional information.

What if the dosage, quantity, or drug name of the jardiance coupon I downloaded is different than what I’m trying to fill right now?

Any downloaded USA Rx coupon can be applied to any prescription drug at a participating pharmacy and receive a discount with our maximum savings.

Does this coupon work for brand name drug and the generic version?

Yes, both generic and brand prescription medication are covered by the coupon. Remember, any coupon can be applied to any prescription drug at a participating pharmacy and receive a discount with maximum savings.

Is this a drug manufacturer rebate?

No, this is not a rebate.

Does this work with my insurance coverage?

No, you must decide at the pharmacy either to use your USA Rx Jardiance coupon or your insurance.  

Do I have to show my coupon consecutive months at the pharmacy?

We recommend you show the coupon when possible, but the pharmacy should keep your coupon information in their system.

Jardiance Prescription Medication Savings Explained 

FAQ Disclaimer: USA Rx LLC has a full endorsement of our prescription savings discount program. This product does not replace your insurance plan or your insurance coverage. You may check the price of both your insurance plan (copay) and our patient assistance program. That is an easy step to get the lowest price and out of pocket cost on your prescriptions. We always strive to give you a maximum savings. This is not a rebate. If you have a medical condition and need assistance with figuring out your best option for a discount program or prescription savings, please give us a call or drop us an email for additional information. If you need medical help, please seek proper medical care as soon as possible. Chat with your doctor or pharmacist about all possible side effects. All cardholders adhere to our privacy policy. We use recent information to create our pricing estimates, which are subject to change. Prescription Prices are subject to change. Our affiliates use the “powered by USA Rx” symbol in marketing materials.