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Januvia

Januvia Prescription
Generic Name: sitagliptin (SI ta glip tin)
Brand Names: Januvia
Januvia is used to treat type 2 diabetes. Learn about side effects, interactions and indications.
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Januvia Drug Information:

Januvia (sitagliptin) is an oral Diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Januvia is used together with diet and exercise to improve blood sugar control in adults with type 2 Diabetes mellitus. Januvia is not for treating type 1 Diabetes. You should not use Januvia if you are in a state of Diabetic ketoacidosis (call your doctor for treatment with insulin). Call your doctor if you have symptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain. Learn more

Buy Januvia Online and Januvia Delivery

USARx offers the following ways to purchase this medication. Choose the Best option for you!

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    Local Pharmacy Pickup of Januvia

    Pay this amount and pick up your prescription at ANY Retail pharmacy of your choice! Walgreens, CVS, Walmart, etc.

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    Mail Order Home Delivery of Januvia

    The easiest way to receive your medications.

Januvia Medicare Coverage

Januvia Medicare Overview

Does Medicare cover Januvia?

Yes

95% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Januvia co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…

CO-PAY RANGE

$42 – $544

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Januvia

Here are some ways that may lower the cost of your januvia prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Januvia Side Effects

Note: This document contains side effect information about sitagliptin. Some of the dosage forms listed on this page may not apply to the brand name Januvia.

For the Consumer

Applies to sitagliptin: oral tablet

Along with its needed effects, sitagliptin (the active ingredient contained in Januvia) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sitagliptin:

Less common

  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fast heartbeat
  • headache
  • increased hunger
  • loss of consciousness
  • nausea
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • unusual tiredness or weakness

Incidence not known

  • Blistering, peeling, loosening of the skin
  • diarrhea
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • redness of the skin
  • severe joint pain
  • sores, ulcers, or white spots in the mouth or on the lips
  • vomiting

Some side effects of sitagliptin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Body aches or pain
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • loss of voice
  • muscle aches
  • sneezing
  • sore throat
  • stuffy or runny nose

Less common

  • Diarrhea
  • stomach pain

For Healthcare Professionals

Applies to sitagliptin: oral tablet

Metabolic

Common (1% to 10%): Hypoglycemia (when used in combination with insulin or sulfonylurea)

Gastrointestinal

In a pooled analysis of 19 trials (sitagliptin (the active ingredient contained in Januvia) 100 mg/day, n=5429; active control or placebo, n=4817), the incidence of acute pancreatitis was in 0.1 per 100 patient-years in each group (4 patients in each group)

Common (1% to 10%): Abdominal pain, nausea, diarrhea, constipation, gastroenteritis

Postmarketing reports: Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, vomiting, mouth ulceration, stomatitis

Respiratory

Common (1% to 10%): Nasopharyngitis, upper respiratory infection, pharyngitis,

Postmarketing reports: Interstitial lung disease

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness

Hypersensitivity

There have been postmarketing reports of serious hypersensitivity reactions in patients treated with this drug. Reactions have occurred within the first 3 months of therapy initiation, with some reports occurring after the first dose.

Postmarketing reports: Serious hypersensitivity reactions including anaphylaxis, angioedema, rash, urticaria, cutaneous vasculitis, and exfoliative skin conditions including Stevens-Johnson syndrome

Hepatic

Postmarketing reports: Hepatic enzyme elevations

Renal

There have been postmarketing reports of worsening renal function, including acute renal failure, sometime requiring dialysis. A subset of these reports involved patients with renal insufficiency, some who were prescribed inappropriate doses of this drug. With drug discontinuation, supportive treatment and discontinuation of potentially causative agents, a return to baseline levels of renal insufficiency occurred.

Postmarketing reports: Worsening renal function

Musculoskeletal

Postmarketing reports: Arthralgia, myalgia, extremity pain, back pain, osteoarthritis, rhabdomyolysis

Between October 2006 and December 2013, thirty-three cases of severe arthralgia have been reported to the FDA Adverse Event Reporting System Database. Each case involved the use of 1 or more dipeptidyl peptidase-4 (DPP-4) inhibitors. In all cases, substantial reduction in prior activity level was reported, 10 patients were hospitalized due to disabling joint pain. In 22 cases, symptoms appeared within 1 month of starting therapy. In 23 cases symptoms resolved less than 1 month after discontinuation. A positive rechallenge was reported in 8 cases, with 6 cases involving use of a different DPP-4 inhibitor. Sitagliptin had the greatest number of cases reported (n=28) followed by saxagliptin (n=5), linagliptin (n=2), alogliptin (n=1), and vildagliptin (n=2).

Cardiovascular

Common (1% to 10%): Hypertension

Dermatologic

Postmarketing reports: Pruritus

General

The most commonly reported adverse events included upper respiratory tract infection, nasopharyngitis, and headache. As add-on to insulin studies, hypoglycemia was commonly reported.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Januvia (www.drugs.com/januvia.html).