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Jantoven is an anticoagulant (blood thinner). This medicine reduces the formation of blood clots.
Jantoven is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.
Jantoven may also be used for purposes not listed in this medication guide.
You should not take Jantoven if you are prone to bleeding because of a medical condition, if you have an upcoming surgery, or if you need a spinal tap or epidural. Do not take this medicine if you cannot take it on time every day.
Jantoven increases your risk of severe or fatal bleeding, especially if you have certain medical conditions, if you are 65 or older, or if you have had a stroke, or bleeding in your stomach or intestines. Seek emergency help if you have any bleeding that will not stop.
Call your doctor at once if you have other signs of bleeding such as: swelling, pain, feeling very weak or dizzy, unusual bruising, bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.
Many other drugs can increase your risk of bleeding when used with Jantoven. Tell your doctor about all medicines you have recently used.
Avoid making any changes in your diet without first talking to your doctor. Some foods can make Jantoven less effective.
You should not take Jantoven if you are allergic to it, or if:
you have very high blood pressure;
you recently had or will have surgery on your brain, spine, or eye;
you undergo a spinal tap or spinal anesthesia (epidural); or
you cannot take Jantoven on time every day.
You also should not take Jantoven if you are are prone to bleeding because of a medical condition, such as:
a blood cell disorder (such as low red blood cells or low platelets);
ulcers or bleeding in your stomach, intestines, lungs, or urinary tract;
an aneurysm or bleeding in the brain; or
an infection of the lining of your heart.
Do not take Jantoven if you are pregnant, unless your doctor tells you to. This medicine can cause birth defects, but preventing blood clots may outweigh any risks to the baby. If you are not pregnant, use effective birth control to prevent pregnancy while taking this medicine and for at least 1 month after your last dose. Tell your doctor right away if you become pregnant.
Jantoven can make you bleed more easily, especially if you have ever had:
high blood pressure or serious heart disease;
kidney disease;
cancer or low blood cell counts;
an accident or surgery;
bleeding in your stomach or intestines;
a stroke; or
if you are 65 or older.
To make sure Jantoven is safe for you, tell your doctor if you have ever had:
diabetes;
congestive heart failure;
liver disease, kidney disease (or if you are on dialysis);
a hereditary clotting deficiency; or
low blood platelets after receiving heparin.
It is not known whether warfarin passes into breast milk. Watch for signs of bruising or bleeding in the baby if you take warfarin while you are breast-feeding a baby.
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take Jantoven in larger or smaller amounts or for longer than your doctor tells you to.
Take Jantoven at the same time every day, with or without food. Never take a double dose.
Jantoven can make it easier for you to bleed. Seek emergency help if you have any bleeding that will not stop.
You will need frequent "INR" or prothrombin time tests (to measure your blood-clotting time and determine your Jantoven dose). You must remain under the care of a doctor while taking this medicine.
If you receive Jantoven in a hospital, call or visit your doctor 3 to 7 days after you leave the hospital. Your INR will need to be tested at that time. Do not miss any follow-up appointments.
Tell your doctor if you are sick with diarrhea, fever, chills, or flu symptoms, or if your body weight changes.
You may need to stop taking Jantoven 5 to 7 days before having any surgery, dental work, or a medical procedure. Call your doctor for instructions.
Wear a medical alert tag or carry an ID card stating that you take Jantoven. Any medical care provider who treats you should know that you are taking Jantoven.
Store at room temperature away from heat, moisture, and light.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause excessive bleeding.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. You may still bleed more easily for several days after you stop taking Jantoven.
Avoid making any changes in your diet without first talking to your doctor. Foods that are high in vitamin K (liver, leafy green vegetables, or vegetable oils) can make Jantoven less effective. If these foods are part of your diet, eat a consistent amount on a weekly basis.
Grapefruit juice, cranberry juice, noni juice, and pomegranate juice may interact with Jantoven and lead to unwanted side effects. Avoid the use of these juice products while taking this medicine.
Avoid drinking alcohol.
Ask your doctor before using any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. These medicines may affect blood clotting and may also increase your risk of stomach bleeding.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Jantoven increases your risk of bleeding, which can be severe or life-threatening. Call your doctor at once if you have any signs of bleeding such as:
sudden headache, feeling very weak or dizzy;
swelling, pain, unusual bruising;
bleeding gums, nosebleeds;
bleeding from wounds or needle injections that will not stop;
heavy menstrual periods or abnormal vaginal bleeding;
blood in your urine, bloody or tarry stools; or
coughing up blood or vomit that looks like coffee grounds.
Clots formed by Jantoven may block normal blood flow, which could lead to tissue death or amputation of the affected body part. Get medical help at once if you have:
pain, swelling, hot or cold feeling, skin changes, or discoloration anywhere on your body; or
sudden and severe leg or foot pain, foot ulcer, purple toes or fingers.
Bleeding is the most common side effect of warfarin.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Many drugs (including some over-the-counter medicines and herbal products) can affect your INR and may increase the risk of bleeding if you take them with Jantoven. Not all possible drug interactions are listed in this medication guide. It is very important to ask your doctor and pharmacist before you start or stop using any other medicine, especially:
other medicines to prevent blood clots;
an antibiotic or antifungal medicine;
supplements that contain vitamin K; or
herbal (botanical) products--coenzyme Q10, cranberry, echinacea, garlic, ginkgo biloba, ginseng, goldenseal, or St. John's wort.
This list is not complete and many other drugs can interact with Jantoven. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Jantoven (www.drugs.com/mtm/jantoven.html).
Note: This document contains side effect information about warfarin. Some of the dosage forms listed on this page may not apply to the brand name Jantoven.
Applies to warfarin: oral tablet
Oral route (Tablet)
Warfarin can cause major or fatal bleeding. Regular monitoring of INR should be performed on all treated patients. Drugs, dietary changes, and other factors affect INR levels achieved with warfarin sodium therapy. Instruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleeding.
Along with its needed effects, warfarin (the active ingredient contained in Jantoven) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking warfarin:
Less common
Rare
Some side effects of warfarin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Rare
Applies to warfarin: compounding powder, intravenous powder for injection, oral tablet
The most common adverse reactions were fatal and nonfatal hemorrhage from any tissue or organ.
Frequency not reported: Hemorrhage, purple toes syndrome, infarction, systemic cholesterol microembolization, vasculitis, systemic atheroemboli
Frequency not reported: Cerebral hemorrhage, cerebral subdural hematoma, lethargy, headache, dizziness, taste perversion, paresthesia
Frequency not reported: Gastrointestinal hemorrhage, rectal hemorrhage, hematemesis, pancreatitis, diarrhea, nausea, vomiting, melena, abdominal pain, cramping, flatulence, bloating
Frequency not reported: Rash, alopecia, purpura, erythematous swollen skin patches, ecchymosis, skin necrosis, dermatitis, bullous eruptions, urticaria, pruritus
Frequency not reported: Tissue necrosis, chills
Frequency not reported: Calciphylaxis, edema
Frequency not reported: Hemothorax, epistaxis, tracheal or tracheobronchial calcification
Frequency not reported: Hematuria
Frequency not reported: Unexplained decrease in hematocrit, hemoglobin decreased
Frequency not reported: Jaundice, hepatic dysfunction, hepatitis, cholestatic hepatic injury, liver enzymes elevated
Frequency not reported: Hypersensitivity, allergic reactions, anaphylactic reactions
Frequency not reported: Fever, fatigue, malaise, asthenia, pain, cold intolerance, feeling cold
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Jantoven (www.drugs.com/mtm/jantoven.html).
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