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Ipratropium Bromide

Ipratropium bromide Prescription
Generic Name: ipratropium nasal (IP ra TRO pee um)
Brand Name: Atrovent Nasal
Physician reviewed ipratropium nasal patient information - includes ipratropium nasal description, dosage and directions.

Average Savings for ipratropium bromide (generic): 49.58%
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Ipratropium Bromide Drug Information:

IpratrOpium nasal (for the nose) works by reducing mucus secretions in the nose. IpratrOpium nasal is used to treat runny nose caused by seasonal allergies (hay fever). ipratrOpium nasal will not treat stuffy nose, sneezing, or cough. IpratrOpium nasal may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare prOviders about all your medical conditions, allergies, and all medicines you use. You should not use ipratrOpium nasal if you are allergic to ipratrOpium or atropine. Learn more

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Ipratropium Bromide Side Effects

For the Consumer

Applies to ipratropium nasal: nasal spray

Side effects requiring immediate medical attention

Along with its needed effects, ipratropium nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ipratropium nasal:

For the 0.03% nasal spray

More common

  • Body aches or pain
  • chills
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • runny nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness

Less common

  • Blurred vision
  • burning, dry, or itching eyes
  • discharge or excessive tearing
  • itching, redness, tearing, or other sign of eye irritation not present before use of this medicine or becoming worse during use
  • nasal dryness
  • nosebleeds
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid


  • Pain or cramping in the abdomen or stomach
  • painful or difficult urination

Incidence not known

  • Difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives or welts
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • skin rash
  • tightness in the chest

For the 0.06% nasal spray used for 4 days

Less common

  • Nasal dryness
  • nosebleeds


  • Blurred vision
  • dizziness
  • eye redness or pain
  • fast, slow, or irregular heartbeat
  • pain or cramping in the abdomen or stomach
  • painful or difficult urination
  • ringing or buzzing in the ears
  • sore throat
Side effects not requiring immediate medical attention

Some side effects of ipratropium nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For the 0.03% nasal spray

Less common or rare

  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • dry mouth or throat
  • increased nasal congestion or runny nose
  • nasal itching, burning, or irritation
  • nausea

For the 0.06% nasal spray

Less common or rare

  • Dry mouth or throat
  • increased nasal congestion

For Healthcare Professionals

Applies to ipratropium nasal: nasal spray


Additional side effects have been reported from published literature and/or postmarketing surveillance when this drug was used alone or in combination with albuterol, including: urinary retention, prostatic disorders, mydriasis, cases of precipitation or worsening of narrow-angle glaucoma, acute eye pain, ocular irritation, wheezing, dryness of the oropharynx, tachycardia, edema, gastrointestinal distress (diarrhea, nausea, vomiting), bowel obstruction, constipation, nasal discomfort, throat irritation, hypersensitivity, accommodation disorder, intraocular pressure increased, glaucoma, halo vision, conjunctival hyperemia, corneal edema, heart rate increased, bronchospasm, pharyngeal edema, gastrointestinal motility disorder, mouth edema, stomatitis, and pruritus. After oral inhalation in patients suffering from chronic obstructive pulmonary disease (COPD)/asthma, supraventricular tachycardia and atrial fibrillation have been reported.

The most frequently reported side effects were nasal dryness, epistaxis, headache, nasal discomfort, and throat irritation.


Common (1% to 10%): Upper respiratory tract infection, epistaxis, nasal dryness, nasal irritation, nasal congestion, rhinorrhea increased, rhinitis increased, posterior nasal drip, sneezing, nasal polyps, nasal edema, pharyngitis, sinusitis, nasal discomfort, ulcerative rhinitis

Uncommon (0.1% to 1%): Bronchospasm, laryngospasm, pharyngeal edema

Frequency not reported: Hoarseness, cough, nasal burning


Uncommon (0.1% to 1%): Vision blurred, mydriasis, intraocular pressure increased, glaucoma, eye pain, halo vision, conjunctival hyperemia, corneal edema, accommodation disorder

Frequency not reported: Ocular irritation, conjunctivitis


Frequency not reported: Irritation

Nervous system

Common (1% to 10%): Headache, taste perversion

Uncommon (0.1% to 1%): Dizziness


Uncommon (0.1% to 1%): Urinary retention


Uncommon (0.1% to 1%): Supraventricular tachycardia, atrial fibrillation, heart rate increased

Rare (less than 0.1%): Palpitation

Frequency not reported: Tachycardia


Common (1% to 10%): Nausea, dry mouth/throat, diarrhea, throat irritation

Uncommon (0.1% to 1%): Gastrointestinal motility disorder, stomatitis

Frequency not reported: Dry mouth/throat


Uncommon (0.1% to 1%): Angioedema of throat/tongue/lips/face, rash

Rare (less than 0.1%): Urticaria, pruritus


Uncommon (0.1% to 1%): Hypersensitivity, anaphylactic reaction


Common (1% to 10%): Pain

Frequency not reported: Thirst, tinnitus

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Ipratropium Bromide (www.drugs.com/mtm/ipratropium-nasal.html).