Commonly reported side effects of gemfibrozil include: malignant neoplasm, pancreatitis, dyspepsia, and cholelithiasis. Other side effects include: abdominal pain. See below for a comprehensive list of adverse effects.
Applies to gemfibrozil: oral tablet
Along with its needed effects, gemfibrozil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking gemfibrozil:
Incidence not known
Some side effects of gemfibrozil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to gemfibrozil: compounding powder, oral tablet
The most frequently reported side effects were gastrointestinal reactions and included dyspepsia, abdominal pain, diarrhea, nausea, vomiting, acute appendicitis, constipation, and flatulence.
Very common (10% or more): Dyspepsia (19.6%)
Common (1% to 10%): Abdominal pain, acute appendicitis, diarrhea, nausea, vomiting, constipation, flatulence
Rare (less than 0.1%): Pancreatitis
Frequency not reported: Colitis
Common (1% to 10%): Headache
Rare (less than 0.1%): Peripheral neuropathy, paresthesia, dizziness, somnolence
Frequency not reported: Peripheral neuritis, convulsions, syncope, hyperesthesia, taste perversion, intracerebral hemorrhage
Rare (less than 0.1%): Hepatitis, cholestatic jaundice, cholelithiasis, cholecystitis, hepatic function abnormal
Frequency not reported: ALT increased, AST increased, bilirubin increased, alkaline phosphatase increased
Uncommon (0.1% to 1%): Atrial fibrillation
Frequency not reported: Extrasystoles, vasculitis, peripheral vascular disease
Common (1% to 10%): Eczema, rash
Rare (less than 0.1%): Angioedema, urticaria, exfoliative dermatitis, dermatitis, pruritus, alopecia, photosensitivity reaction
Common (1% to 10%): Fatigue, vertigo
Rare (less than 0.1%): Creatine phosphokinase increased
Frequency not reported: Weight loss, viral infections, bacterial infections
Rare (less than 0.1%): Myopathy, myalgia, painful extremities, arthralgia, synovitis, rhabdomyolysis, myositis, muscular weakness
Frequency not reported: Lupus-like syndrome, myasthenia
Rare (less than 0.1%): Bone marrow failure, severe anemia, thrombocytopenia, leukopenia, eosinophilia, hemoglobin decreased, hematocrit decreased, WBC decreased
Frequency not reported: Anemia, bone marrow hypoplasia
Rare (less than 0.1%): Blurred vision
Frequency not reported: Retinal edema, cataracts
Rare (less than 0.1%): Erectile dysfunction
Frequency not reported: Impotence, male fertility decreased
Rare (less than 0.1%): Libido decreased, depression
Frequency not reported: Confusion
Rare (less than 0.1%): Laryngeal edema
Frequency not reported: Renal dysfunction, renal failure
Frequency not reported: Hepatoma
Frequency not reported: Positive antinuclear antibody, anaphylaxis
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Gemfibrozil (www.drugs.com/gemfibrozil.html).