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Forteo

Generic Name: teriparatide (ter i PAR a tide)
Brand Names: Forteo
Forteo (teriparatide) is used to treat osteoporosis. Learn about side effects, interactions and indications.
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Drug Information:
Forteo (teriparatide) is a man-made form of paraThyroid hormone that exists naturally in the body. Teriparatide increases bone mineral density and bone strength, which may prevent fractures. Forteo is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Forteo is for use when you have a high risk of bone fracture due to osteoporosis. Forteo has caused bone cancer (osteosarcoma) in animals but it is not known whether this would occur in people using this medicine. Talk with your doctor about your own risk. Learn more

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Forteo Side Effects

Note: This document contains side effect information about teriparatide. Some of the dosage forms listed on this page may not apply to the brand name Forteo.

In Summary

Common side effects of Forteo include: arthralgia, pain, and rhinitis. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to teriparatide: subcutaneous solution

Warning

Subcutaneous route (Solution)

In male and female rats, teriparatide caused an increase in the incidence of osteosarcoma that was dependent on dose and treatment duration. Teriparatide should not be prescribed for patients who are at increased baseline risk for osteosarcoma (including those with Paget's disease of bone or unexplained elevations of alkaline phosphatase, open epiphyses, or prior external beam or implant radiation therapy involving the skeleton).

Along with its needed effects, teriparatide (the active ingredient contained in Forteo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as bone cancer. Discuss these possible effects with your doctor.

Check with your doctor immediately if any of the following side effects occur while taking teriparatide:

More common

  • Abdominal pain
  • confusion
  • constipation
  • depression
  • dry mouth
  • headache
  • incoherent speech
  • increased urination
  • loss of appetite
  • metallic taste
  • muscle weakness
  • nausea
  • thirst
  • unusual tiredness
  • vomiting
  • weight loss

Less common

  • Arm, back, or jaw pain
  • chest pain or discomfort
  • chest tightness or heaviness
  • cough
  • difficult or labored breathing
  • fainting
  • fast or irregular heartbeat
  • fever or chills
  • nausea
  • shortness of breath
  • sneezing
  • sore throat
  • sweating
  • tightness in the chest
  • wheezing

Incidence not known

  • Hives or welts
  • itching
  • redness of the skin
  • skin rash
  • swelling or puffiness of the mouth and face

Some side effects of teriparatide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Acid or sour stomach
  • belching
  • blurred vision
  • body aches or pain
  • congestion
  • diarrhea
  • difficulty having a bowel movement (stool)
  • difficulty with moving
  • dizziness
  • heartburn
  • hoarseness
  • indigestion
  • lack or loss of strength
  • muscle pain or stiffness
  • muscle spasm
  • nervousness
  • pain in the joints
  • pounding in the ears
  • runny nose
  • tender, swollen glands in the neck
  • trouble with swallowing
  • voice changes

Less common

  • Abdominal or stomach cramps
  • back pain
  • discomfort
  • discouragement
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • indigestion
  • irritability
  • lack of appetite
  • leg cramps
  • loss of interest or pleasure
  • neck pain
  • rash
  • sensation of spinning
  • sleeplessness
  • swollen mouth and tongue
  • tiredness
  • tooth disorder
  • trouble concentrating
  • trouble sleeping
  • unpleasant taste
  • urge to have bowel movement

Rare

  • Pain at the place of injection during or following the injection
  • tingling feeling in the hands and feet
  • urge for bowel movement

Incidence not known

  • Bruising at the injection site
  • flushing
  • minor bleeding at the injection site
  • unusually warm skin

For Healthcare Professionals

Applies to teriparatide: subcutaneous solution

Cardiovascular

Common (1% to 10%): Hypotension, hypertension, palpitations, chest pain, angina pectoris

Uncommon (0.1% to 1%): Tachycardia, cardiac murmur

Frequency not reported: Peripheral edema

Gastrointestinal

Common (1% to 10%): Nausea, vomiting, hiatus hernia, gastro-esophageal reflux disease, constipation, diarrhea, dyspepsia, gastrointestinal disorder, tooth disorder

Uncommon (0.1% to 1%): Hemorrhoids

Musculoskeletal

Very common (10% or more): Pain in limb, arthralgia (10%)

Common (1% to 10%): Muscle cramps, neck pain, leg cramps

Uncommon (0.1% to 1%): Myalgia, arthralgia, back cramp/pain

Nervous system

Common (1% to 10%): Dizziness, headache, sciatica, syncope

Respiratory

Common (1% to 10%): Dyspnea, rhinitis, cough increased, pharyngitis, pneumonia

Uncommon (0.1% to 1%): Emphysema

Dermatologic

Common (1% to 10%): Rash, sweating increased

Endocrine

Frequency not reported: Transient hypoparathyroidism

Hypersensitivity

Rare (less than 0.1%): Anaphylaxis, possible allergic events soon after injection (e.g., acute dyspnea, oro/facial edema, generalized urticaria, chest pain, edema (mainly peripheral)

Postmarketing reports: Drug hypersensitivity, angioedema, urticaria

Hematologic

Common (1% to 10%): Anemia

Local

Common (1% to 10%): Mild and transient injection site events (e.g., pain, swelling, erythema, localized bruising, pruritus, minor bleeding at injection site)

Uncommon (0.1% to 1%): Injection site erythema, injection site reaction

Metabolic

Common (1% to 10%): Hypercholesterolemia

Uncommon (0.1% to 1%): Hypercalcemia (greater than 2.76 mmol/L), hyperuricemia, weight gain, alkaline phosphatase increase

Other

Very common (10% or more): Pain (21%)

Common (1% to 10%): Vertigo, fatigue, asthenia, syncope

Psychiatric

Common (1% to 10%): Depression, insomnia

Renal

Uncommon (0.1% to 1%): Urinary incontinence, polyuria, micturition urgency, nephrolithiasis

Rare (less than 0.1%): Renal failure/impairment

Oncologic

Frequency not reported: Osteosarcoma

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Forteo (www.drugs.com/forteo.html).