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Fluvoxamine Maleate Er

Fluvoxamine maleate er Prescription
Generic Name: fluvoxamine (floo VOX a meen)
Brand Name: Luvox, Luvox CR
Physician reviewed fluvoxamine patient information - includes fluvoxamine description, dosage and directions.

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Fluvoxamine Maleate Er Drug Information:

Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Fluvoxamine affects chemicals in the brain that may be unbalanced in people with obsessive-compulsive symptoms. Fluvoxamine is used to treat social anxiety disorder (social phobia), or obsessive-compulsive disorders involving recurring thoughts or actions. Fluvoxamine may also be used for purposes not listed in this medication guide. You should not take fluvoxamine if you are also using alosetron, Pimozide, Ramelteon, thioridazine, or tizanidine. Learn more

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Fluvoxamine Maleate Er Side Effects

In Summary

Commonly reported side effects of fluvoxamine include: asthenia, diarrhea, dizziness, drowsiness, dyspepsia, insomnia, nausea, nervousness, constipation, headache, anorexia, and xerostomia. Other side effects include: anorgasmia, tremor, vomiting, diaphoresis, flushing, and ecchymoses. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to fluvoxamine: oral capsule extended release, oral tablet


Oral route (Capsule, Extended Release; Tablet)

Antidepressants can increase the risk of suicidal thinking and behavior in children, adolescents, and young adults with major depressive disorder and other psychiatric disorders. This risk was not observed in patients older than 24 years, and the risk was reduced in patients 65 years or younger. Closely monitor patients of all ages for clinical worsening and emergence of suicidal thoughts and behaviors.. Fluvoxamine maleate tablets are not approved for use in pediatric patients except for patients with obsessive compulsive disorder.

Side effects requiring immediate medical attention

Along with its needed effects, fluvoxamine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fluvoxamine:

Less common

  • Behavior, mood, or mental changes
  • trouble with breathing
  • trouble with urinating
  • twitching


  • Absence of or decrease in body movements
  • agitation
  • blurred vision
  • chills
  • clumsiness or unsteadiness
  • confusion
  • convulsions (seizures)
  • diarrhea
  • fever
  • inability to move the eyes
  • increase in body movements
  • menstrual changes
  • nosebleeds
  • overactive reflexes
  • poor coordination
  • red or irritated eyes
  • redness, tenderness, itching, burning, or peeling of the skin
  • restlessness
  • shivering
  • skin rash
  • sore throat
  • sweating
  • talking or acting with excitement you cannot control
  • trembling or shaking
  • unusual bruising
  • unusual, incomplete, or sudden body or facial movements
  • unusual secretion of milk (in females)
  • weakness
Side effects not requiring immediate medical attention

Some side effects of fluvoxamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Change in sexual performance or desire
  • constipation
  • headache
  • trouble sleeping
  • unusual tiredness

Less common

  • Abdominal or stomach pain
  • change in sense of taste
  • decreased appetite
  • feeling of constant movement of self or surroundings
  • frequent urination
  • heartburn
  • increased sweating
  • unusual weight gain or loss

For Healthcare Professionals

Applies to fluvoxamine: oral capsule extended release, oral tablet


The most commonly reported side effects included nausea, headache, insomnia, and somnolence.


Very common (10% or more): Nausea (up to 40%), diarrhea (up to 18%), dry mouth (up to 14%), constipation (up to 10%), dyspepsia (up to 10%)

Common (1% to 10%): Abdominal pain, abscess, caries, dysphagia, flatulence, gingivitis, toothache, tooth extraction, tooth disorder, vomiting

Uncommon (0.1% to 1%): Colitis, eructation, esophagitis, gastritis, gastroenteritis, gastrointestinal hemorrhage, gastrointestinal ulcer, glossitis, hemorrhoids, increased salivation, melena, rectal hemorrhage, stomatitis

Rare (0.01% to 0.1%): Fecal incontinence, hematemesis, intestinal obstruction

Frequency not reported: Dental pain

Postmarketing reports: Gastroesophageal reflux disease, glossodynia, ileus, pancreatitis

Nervous system

Very common (10% or more): Headache (up to 35%), somnolence (up to 27%), asthenia (up to 26%), dizziness (up to 15%)

Common (1% to 10%): Amnesia, central nervous system (CNS) stimulation, hyperkinesia, hypokinesia, hypertonia, myoclonus, paresthesia, syncope, tremor

Uncommon (0.1% to 1%): Akathisia, ataxia, CNS depression, convulsion, dyskinesia, dystonia, extrapyramidal syndrome, hemiplegia, hypersomnia, hypotonia, incoordination, paralysis, parosmia, stupor, taste loss, unsteady gait, vertigo, visual field defect

Rare (0.01% to 0.1%): Akinesia, cerebrovascular accident, coma, decreased reflexes, fibrillations, slurred speech, tardive dyskinesia

Frequency not reported: Dysgeusia, electric shock sensation, neuroleptic malignant syndrome-like events, psychomotor restlessness, sensory disturbance, serotonin syndrome, taste perversion

Postmarketing reports: Dysarthria, gait disturbance, lethargy, loss of consciousness, neonatal somnolence, Parkinsonism


Very common (10% or more): Insomnia (up to 35%), nervousness (up to 12%), decreased male libido (up to 10%)

Common (1% to 10%): Abnormal dreams, abnormal thinking, agitation, anorgasmia, anxiety, apathy, decreased female libido, decreased libido, depression, female anorgasmia, male anorgasmia, manic reaction, neuroses, psychotic reaction

Uncommon (0.1% to 1%): Aggression, agoraphobia, confusion/confusional state, delirium, delusion, depersonalization, emotional instability/lability, euphoria, hallucinations, hostility, hypochondriasis, hysteria, increased libido, paranoid reaction, phobia, psychosis, sleep disorder, suicidal tendency, suicide attempt

Rare (0.01% to 0.1%): Mania, mutism, obsessions, withdrawal syndrome

Frequency not reported: Hypomania, intense dreams, irritability, sleep disturbances, suicidal behavior, suicidal ideation

Postmarketing reports: Activation syndrome, anger, bruxism, homicidal ideation, impulsive behavior, self-injurious behavior


Very common (10% or more): Anorexia (up to 14%)

Common (1% to 10%): Decreased appetite, loss of appetite, weight gain, weight loss

Uncommon (0.1% to 1%): Dehydration, hypercholesterolemia

Rare (0.01% to 0.1%): Diabetes mellitus, hyperglycemia, hyperlipidemia, hypoglycemia, hypokalemia, increased lactate dehydrogenase

Frequency not reported: Hyponatremia, increased appetite, porphyria, thirst


Very common (10% or more): Abnormal ejaculation (up to 11%)

Common (1% to 10%): Abnormal female sexual function, abnormal male sexual function, delayed ejaculation, impotence, menorrhagia, polyuria, urinary frequency, urinary retention, urinary tract infection

Uncommon (0.1% to 1%): Anuria, delayed menstruation, dysuria, female lactation, hematospermia, hematuria, impaired urination, menopause, metrorrhagia, nocturia, premenstrual syndrome, vaginal hemorrhage, vaginitis

Rare (0.01% to 0.1%): Galactorrhea

Frequency not reported: Amenorrhea, dysmenorrhea, enuresis, gynecological hemorrhage, hypomenorrhea, menstrual disorders, micturition disorder, pollakiuria, priapism, urinary incontinence


Very common (10% or more): Pain (up to 10%)

Common (1% to 10%): Accidental injury, asthenia, chills, malaise

Uncommon (0.1% to 1%): Otitis media, overdose

Rare (0.01% to 0.1%): Sudden death

Frequency not reported: Body aches, ear pain, neonatal drug withdrawal syndrome, pain from surgery, unspecified pain

Postmarketing reports: Crying, fall, feeling drunk, feeling jittery, fatigue, pyrexia


Common (1% to 10%): Chest pain, edema, feeling hot, feeling warm, flushing, hypertension, hypotension, palpitations, tachycardia, vasodilation

Uncommon (0.1% to 1%): Angina pectoris, bradycardia, cardiomyopathy, cardiovascular disease, cold extremities, conduction delay, hypotension, irregular pulse, myocardial infarction, orthostatic hypotension, pallor, ST segment changes

Rare (0.01% to 0.1%): Atrioventricular (AV) block, embolus, pericarditis, phlebitis, supraventricular extrasystoles

Frequency not reported: Hemorrhage

Postmarketing reports: Cardiac arrest/fatal cardiac arrest, cardiorespiratory arrest, electrocardiogram QT prolonged, shock, Torsade de pointes, vasculitis, ventricular arrhythmia, ventricular tachycardia


Common (1% to 10%): Bronchitis, cough increased, dyspnea, epistaxis, laryngitis, pharyngitis, sinusitis, upper respiratory infection, yawn

Uncommon (0.1% to 1%): Asthma, hoarseness, hyperventilation

Rare (0.01% to 0.1%): Apnea, hemoptysis, hiccups, laryngismus, obstructive pulmonary disease, pneumonia, pulmonary infarction, upper airway congestion

Frequency not reported: Rhinitis

Postmarketing reports: Interstitial lung disease


Common (1% to 10%): Acne, ecchymosis, hyperhidrosis, sweating

Uncommon (0.1% to 1%): Alopecia, angioneurotic edema, cutaneous hypersensitivity reactions, dry skin, eczema, exfoliative dermatitis, furunculosis, photosensitivity reaction, pruritus, rash, seborrhea, skin discoloration, urticaria

Postmarketing reports: Bullous eruption, Henoch-Schonlein purpura, Stevens-Johnson syndrome, toxic epidermal necrolysis


Common (1% to 10%): Myalgia, twitching

Uncommon (0.1% to 1%): Arthralgia, arthritis, bursitis, generalized muscle spasm, myasthenia, neck pain, neck rigidity

Rare (0.01% to 0.1%): Myopathy, torticollis, trismus

Frequency not reported: Back pain, bone fractures, general pain secondary to injuries (sprains, fractures), leg cramps

Postmarketing reports: Muscular weakness, rhabdomyolysis


Common (1% to 10%): Amblyopia, blurred vision

Uncommon (0.1% to 1%): Abnormal accommodation, conjunctivitis, diplopia, dry eyes, eye pain, mydriasis, photophobia

Rare (0.01% to 0.1%): Corneal ulcer

Frequency not reported: Glaucoma, visual disturbance


Common (1% to 10%): Abnormal liver function, elevated liver transaminases

Rare (0.01% to 0.1%): Biliary pain, cholecystitis, cholelithiasis, jaundice

Postmarketing reports: Hepatitis


Common (1% to 10%): Flu syndrome, viral infection

Frequency not reported: Infection


Uncommon (0.1% to 1%): Anemia, leukocytosis, lymphadenopathy, thrombocytopenia

Rare (0.01% to 0.1%): Leukopenia, purpura

Postmarketing reports: Agranulocytosis, aplastic anemia, decreased white blood cell count


Uncommon (0.1% to 1%): Cystitis

Rare (0.01% to 0.1%): Kidney calculus, oliguria

Postmarketing reports: Acute renal failure, renal impairment


Uncommon (0.1% to 1%): Hypothyroidism

Rare (0.01% to 0.1%): Goiter

Frequency not reported: Hyperprolactinemia, inappropriate antidiuretic hormone secretion/SIADH


Uncommon (0.1% to 1%): Allergic reaction

Postmarketing reports: Anaphylactic reaction, angioedema

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Fluvoxamine Maleate Er (www.drugs.com/mtm/fluvoxamine.html).