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Fexmid is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
Fexmid is used together with rest and physical therapy to relieve muscle spasms caused by painful conditions such as an injury.
Fexmid may also be used for purposes not listed in this medication guide.
You should not use Fexmid if you have a thyroid disorder, heart block, congestive heart failure, a heart rhythm disorder, or you have recently had a heart attack.
Do not use Fexmid if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine.
You should not use Fexmid if you are allergic to it, or if you have:
a thyroid disorder;
heart block, heart rhythm disorder, congestive heart failure; or
if you have recently had a heart attack.
Fexmid is not approved for use by anyone younger than 15 years old.
Do not use Fexmid if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Some medicines can interact with Fexmid and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
Tell your doctor if you have ever had:
liver disease;
glaucoma;
enlarged prostate; or
problems with urination.
It is not known whether Fexmid will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Older adults may be more sensitive to the effects of this medicine.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Fexmid is usually taken once daily for only 2 or 3 weeks. Follow your doctor's dosing instructions very carefully.
Swallow the capsule whole and do not crush, chew, break, or open it.
Take the medicine at the same time each day.
Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse.
Store at room temperature away from moisture, heat, and light.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Fexmid can be fatal.
Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations.
Avoid driving or hazardous activity until you know how Fexmid will affect you. Your reactions could be impaired.
Avoid drinking alcohol. Dangerous side effects could occur.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Fexmid and call your doctor at once if you have:
fast or irregular heartbeats;
chest pain or pressure, pain spreading to your jaw or shoulder; or
sudden numbness or weakness (especially on one side of the body), slurred speech, balance problems.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Serious side effects may be more likely in older adults.
Common side effects may include:
drowsiness, tiredness;
headache, dizziness;
dry mouth; or
upset stomach, nausea, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Using Fexmid with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
bupropion (Zyban, for smoking cessation);
meperidine;
tramadol;
verapamil;
cold or allergy medicine that contains an antihistamine (Benadryl and others);
medicine to treat Parkinson's disease;
medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;
medicine to treat overactive bladder; or
bronchodilator asthma medication.
This list is not complete. Other drugs may affect Fexmid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Fexmid (www.drugs.com/mtm/fexmid.html).
Note: This document contains side effect information about cyclobenzaprine. Some of the dosage forms listed on this page may not apply to the brand name Fexmid.
Applies to cyclobenzaprine: oral capsule extended release, oral suspension, oral tablet
Along with its needed effects, cyclobenzaprine (the active ingredient contained in Fexmid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking cyclobenzaprine:
Rare
Get emergency help immediately if any of the following symptoms of overdose occur while taking cyclobenzaprine:
Symptoms of overdose
Some side effects of cyclobenzaprine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common or rare
Applies to cyclobenzaprine: compounding powder, oral capsule extended release, oral tablet, oral and topical kit
The most frequently occurring adverse reactions have included dry mouth, dizziness, fatigue, constipation, nausea, dyspepsia, and somnolence.
Very common (10% or more): Drowsiness (up to 38%)
Common (1% to 10%): Dizziness, somnolence
Postmarketing reports: Headache, serotonin syndrome, seizures, ataxia, tremors, hypertonia, convulsions, abnormal sensations, paresthesia, ageusia
Elderly patients may be particularly susceptible to the sedation and confusion which may accompany cyclobenzaprine therapy.
Common (1% to 10%): Irritability, mental acuity decreased, nervousness
Postmarketing reports: Nervousness, confusion, disorientation, insomnia, depressed mood, anxiety, agitation, psychosis, abnormal thinking and dreaming, hallucinations, excitement
Postmarketing reports: Anaphylaxis, angioedema, pruritus, facial edema, urticaria, rash
Very common (10% or more): Dry mouth (up to 32%)
Common (1% to 10%): Constipation, nausea, dyspepsia, abdominal pain, acid regurgitation, diarrhea
Postmarketing reports: Unpleasant taste, vomiting, anorexia, gastritis, thirst, flatulence, tongue edema
Postmarketing reports: Abnormal liver function, hepatitis, jaundice, cholestasis
Postmarketing reports: Syncope, tachycardia, arrhythmia, vasodilation, palpitation, hypotension
Common (1% to 10%): Fatigue
Postmarketing reports: Asthenia, malaise, vertigo
Postmarketing reports: Sweating
Postmarketing reports: Urinary frequency and/or retention
Postmarketing reports: Local weakness, dysarthria, muscle twitching
Postmarketing reports: Blurred vision, diplopia, tinnitus
Common (1% to 10%): Upper respiratory infection, pharyngitis
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Fexmid (www.drugs.com/mtm/fexmid.html).
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