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Famotidine is a histamine-2 blocker that works by decreasing the amount of acid the stomach produces.
Famotidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.
Famotidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.
Before taking famotidine, tell your doctor if you have kidney or liver disease, a history of Long QT syndrome, stomach cancer or other problems, or asthma, COPD, or other breathing problems.
Famotidine may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor's instructions very closely.
Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the jaw, arm or shoulder, nausea, sweating, anxiety, light-headedness and a general ill feeling.You should not use this medicine if you are allergic to famotidine or similar medicines such as ranitidine (Zantac), cimetidine (Tagamet), or nizatidine (Axid).
To make sure this medicine is safe for you, tell your doctor or pharmacist if you have ever had:
kidney disease;
liver disease;
cancer stomach; or
long QT syndrome (in you or a family member).
Ask a doctor before using famotidine if you are pregnant or breast-feeding.
Use famotidine exactly as directed on the label, or as prescribed by your doctor.
You may take famotidine with or without food.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Most ulcers heal within 4 weeks of treatment, but it may take up to 8 weeks of using this medicine before your ulcer heals. Keep using the medication as directed.
Call your doctor if the condition you are treating with this medicine does not improve, or if it gets worse while using this medicine.
Famotidine may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow all instructions of your doctor or dietitian.
Store at room temperature away from moisture, heat, and light. Do not allow the liquid medicine to freeze.
Throw away any unused liquid that is older than 30 days.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Avoid drinking alcohol. It can increase the risk of damage to your stomach.
Avoid taking other stomach acid reducers unless your doctor has told you to. However, you may take an antacid (such as Maalox, Mylanta, Gaviscon, Milk of Magnesia, Rolaids, or Tums) with famotidine.
Get emergency medical help if you have any signs of an allergic reaction to famotidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
confusion, hallucinations, agitation, lack of energy;
a seizure;
fast or pounding heartbeats, sudden dizziness (like you might pass out); or
unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Some side effects may be more likely in older adults and in people who have severe kidney disease.
Common famotidine side effects may include:
headache;
dizziness; or
constipation or diarrhea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Famotidine can make it harder for your body to absorb other medicines you take by mouth. Tell your doctor if you are taking:
cefditoren;
dasatinib;
delavirdine;
fosamprenavir; or
tizanidine (if you are taking famotidine liquid).
This list is not complete. Other drugs may interact with famotidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use famotidine only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Famotidine (www.drugs.com/famotidine.html).
Applies to famotidine: oral powder for suspension, oral tablet
Along with its needed effects, famotidine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking famotidine:
Rare
Incidence not known
Some side effects of famotidine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Rare
Applies to famotidine: compounding powder, intravenous solution, oral powder for reconstitution, oral tablet, oral tablet chewable, oral tablet disintegrating
The most commonly reported side effects include headache, dizziness, constipation, and diarrhea.
Common (1% to 10%): Constipation, diarrhea
Uncommon (0.1% to 1%): Nausea, vomiting, flatulence, dry mouth, abdominal discomfort or distension
Convulsions occurred in patients with renal dysfunction.
Common (1% to 10%): Headache, dizziness
Very rare (less than 0.01%): Paresthesia, somnolence, epileptic seizures, convulsion
Frequency not reported: Grand mal seizure, taste disorder
Uncommon (0.1% to 1%): Rash, pruritus
Rare (0.01% to 0.1%): Urticaria, angioneurotic edema
Very rare (less than 0.01%): Alopecia, severe skin reactions, toxic epidermal necrolysis, Stevens-Johnson syndrome, epidermal necrolysis
Frequency not reported: Acne, dry skin, flushing
Uncommon (0.1% to 1%): Fatigue
Frequency not reported: Asthenia, fatigue, facial/orbital edema, tinnitus
Uncommon (0.1% to 1%): Loss of appetite
Frequency not reported: Anorexia
Rare (0.01% to 0.1%): Thrombocytopenia, leukopenia, agranulocytosis, pancytopenia
Frequency not reported: Neutropenia
Rare (0.01% to 0.1%): Intrahepatic cholestasis, jaundice, increased liver enzyme abnormalities (transaminases, gamma GT, alkaline phosphatase, bilirubin)
Frequency not reported: Cholestatic jaundice, hepatitis
Rare (0.01% to 0.1%): Hypersensitivity reactions, anaphylaxis
Rare (0.01% to 0.1%): Bronchospasm
Frequency not reported: Interstitial pneumonia
Rare (0.01% to 0.1%): Arthralgia
Very rare (less than 0.01%): Muscle cramps
Frequency not reported: Rhabdomyolysis, musculoskeletal pain
When patients obtained follow-up, psychic disturbances were found to be reversible.
Very rare (less than 0.01%): Hallucinations, disorientation, confusion, anxiety, agitation, depression, reduced libido, insomnia
Frequency not reported: Psychic disturbances
QT interval prolongation occurred in patients with renal dysfunction.
Very rare (less than 0.01%): Chest tightness, prolonged QT interval
Frequency not reported: Arrhythmia, atrioventricular block, palpitation
Very rare (less than 0.01%): Impotence
Frequency not reported: Conjunctival injection
Frequency not reported: Gynecomastia
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Famotidine (www.drugs.com/famotidine.html).
May 12, 2020
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