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Evekeo

Generic Name: amphetamine (am FET a meen)
Brand Name: Adzenys ER, Adzenys XR-ODT, Dyanavel XR, Evekeo, Evekeo ODT
Physician reviewed Evekeo patient information - includes Evekeo description, dosage and directions.
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Drug Information:
Evekeo is a stimulant medicine that is used to treat attention deficit hyperactivity disorder (ADHD). The Evekeo brand of amphetamine is used to treat ADHD and also narcolepsy. Evekeo is sometimes used to treat obesity in people who have not lost weight with diets or other treatments. Evekeo ODT is used only for ADHD. Evekeo may also be used for purposes not listed in this medication guide. Evekeo may be habit-forming. Tell your doctor if you have ever had drug or Alcohol addiction. Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect. Learn more

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Evekeo Side Effects

Note: This document contains side effect information about amphetamine. Some of the dosage forms listed on this page may not apply to the brand name Evekeo.

For the Consumer

Applies to amphetamine: oral suspension extended release, oral tablet, oral tablet extended release disintegrating

Warning

Oral route (Suspension, Extended Release; Tablet, Extended Release, Disintegrating)

CNS stimulants, including amphetamine extended-release oral formulations, other amphetamine-containing products, and methylphenidate, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing and monitor for signs of abuse and dependence while on therapy.

Oral route (Tablet)

Abuse potential is high with the use of amphetamines. Using amphetamines for a prolonged period of time may lead to drug dependence and must be avoided. Pay particular attention to the possibility of patients obtaining amphetamines for distribution to others or for nontherapeutic use. Prescribe and dispense amphetamines sparingly. Sudden death and serious cardiovascular adverse events may occur with misuse of amphetamines.

Along with its needed effects, amphetamine (the active ingredient contained in Evekeo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amphetamine:

More common

  • Agitation
  • anxiety
  • bladder pain
  • bloody or cloudy urine
  • crying
  • delusions of persecution, mistrust, suspiciousness, or combativeness
  • difficult, burning, or painful urination
  • false or unusual sense of well-being
  • feeling of unreality
  • frequent urge to urinate
  • lower back or side pain
  • mental depression
  • nervousness
  • quick to react or overreact emotionally
  • rapidly changing moods
  • sense of detachment from self or body

Less common

  • Chills
  • cough
  • fever
  • hoarseness

Rare

  • Seeing, hearing, or feeling things that are not there
  • severe mental changes

Incidence not known

  • Blurred vision
  • confusion
  • diarrhea
  • dizziness
  • fast, irregular, pounding, or racing heartbeat or pulse
  • headache
  • overactive reflexes
  • pounding in the ears
  • restlessness
  • shakiness in the legs, arms, hands, or feet
  • shivering
  • slow or fast heartbeat
  • sweating
  • talking or acting with excitement you cannot control
  • trouble sleeping
  • twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  • uncontrolled vocal outbursts or tics (uncontrolled repeated body movements)

Get emergency help immediately if any of the following symptoms of overdose occur while taking amphetamine:

Symptoms of overdose

  • Dark urine
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • muscle cramps, spasms, pain, or stiffness
  • nausea
  • seizures
  • stomach cramps
  • sweating
  • unusual tiredness or weakness
  • vomiting

Some side effects of amphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dry mouth
  • loss of appetite
  • sore throat
  • stomach ache
  • voice changes
  • weight loss

Less common

  • Belching
  • dizziness
  • heartburn
  • indigestion
  • stomach discomfort, upset, or pain

Incidence not known

  • Decreased interest in sexual intercourse
  • difficulty having a bowel movement
  • hives or welts, itching, or skin rash
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance
  • redness of the skin
  • unpleasant taste

For Healthcare Professionals

Applies to amphetamine: oral suspension extended release, oral tablet, oral tablet disintegrating, oral tablet disintegrating extended release

General

The most commonly reported side effects with amphetamine (the active ingredient contained in Evekeo) products include dry mouth, anorexia, weight loss, abdominal pain, nausea, insomnia, restlessness, emotional lability, dizziness, and tachycardia.

Cardiovascular

Frequency not reported: Palpitations, tachycardia, elevated blood pressure, cardiomyopathy

Postmarketing reports: Peripheral vasculopathy, myocardial infarction, sudden death, Raynaud's phenomenon

There have been isolated reports of cardiomyopathy associated with chronic amphetamine use.

Hypersensitivity

Postmarketing reports: Hypersensitivity reactions including angioedema and anaphylaxis

Dermatologic

Postmarketing reports: Urticaria, rash, serious skin rashes, including Stevens-Johnson Syndrome and toxic epidermal necrolysis, alopecia

Psychiatric

Rare (less than 0.1%): Psychotic episodes

Frequency not reported: Euphoria, dysphoria, insomnia, restlessness, irritability, depression, aggression, anger, logorrhea, dermatillomania

Nervous system

Frequency not reported: Overstimulation, dizziness, dyskinesia, tremor, headache, exacerbation of motor/phonic tics and Tourette's syndrome, paresthesia, formication

Musculoskeletal

Postmarketing reports: Rhabdomyolysis

Gastrointestinal

Common (1% to 10%): Upper abdominal pain

Frequency not reported: Dry mouth, unpleasant taste, diarrhea, constipation, other GI disturbances, bruxism

Endocrine

Frequency not reported: Impotence, libido changes, frequent or prolonged erections

Immunologic

Frequency not reported: Urticaria

Metabolic

Frequency not reported: Anorexia, weight loss

Respiratory

Common (1% to 10%): Epistaxis, allergic rhinitis

Ocular

Postmarketing reports: Blurred vision, mydriasis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Evekeo (www.drugs.com/mtm/evekeo.html).