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Generic Name: ergotamine (er GOT a meen)
Brand Name: Ergomar
Physician reviewed Ergomar patient information - includes Ergomar description, dosage and directions.
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Drug Information:
Ergomar is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). It works by narrowing the blood vessels around the brain. This medicine also affects blood flow patterns that are associated with certain types of headaches. Ergomar is used to treat a migraine type headache. This medication will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks. Ergomar should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches. Learn more

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Ergomar Side Effects

Note: This document contains side effect information about ergotamine. Some of the dosage forms listed on this page may not apply to the brand name Ergomar.

For the Consumer

Applies to ergotamine: oral tablets, rectal suppositories, sublingual tablets


  • Possible serious and/or life-threatening cerebral and/or peripheral ischemia when used concomitantly with potent CYP3A4 inhibitors (see Interactions); concomitant use contraindicated.

Side effects include:

Nausea, vomiting, abdominal pain, numbness and tingling of the fingers and toes, muscle pain in the extremities, weakness in the legs.

For Healthcare Professionals

Applies to ergotamine: compounding powder, sublingual tablet


The most commonly reported adverse effects have included nausea and vomiting.


Serious vasoconstrictive have occurred, more commonly with long-term therapy at relatively high doses, however, they have been reported with short-term or normal doses.

Nervous system

Reports of cerebral ischemia, including 1 death, have been reported for patients receiving ergotamine (the active ingredient contained in Ergomar) and protease inhibitors concomitantly. A black box warning is now required labeling for these drugs.


Frequency not reported: Ischemia, cyanosis, absence of pulse, cold extremities, precordial distress, EKG changes, gangrene, transient tachycardia, bradycardia, hypertension

Nervous system

Rare (less than 0.1%): Cerebral ischemia

Frequency not reported: Paresthesias, numbness, weakness


Frequency not reported: Nausea, vomiting


Frequency not reported: Musculoskeletal aches, pains, and cramps


Frequency not reported: Vertigo


Frequency not reported: Localized edema, itching

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Ergomar (www.drugs.com/mtm/ergomar.html).