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Emcyt

Generic Name: estramustine (ES tra MUS teen)
Brand Name: Emcyt
Physician reviewed Emcyt patient information - includes Emcyt description, dosage and directions.
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Drug Information:
Emcyt is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Emcyt is used to treat metastatic or progressive prostate cancer. Emcyt may also be used for purposes not listed in this medication guide. You should not use Emcyt if you have a blood clot, swelling of a vein caused by a blood clot, or if you have ever had an allergic Reaction to Estradiol or nitrogen mustard. You should not use Emcyt if you are allergic to it, or if you have: a blood clot; swelling of a vein caused by a blood clot; or Learn more

Emcyt Side Effects

Emcyt Side Effects

Note: This document contains side effect information about estramustine. Some of the dosage forms listed on this page may not apply to the brand name Emcyt.

For the Consumer

Applies to estramustine: oral capsule

Along with its needed effects, estramustine (the active ingredient contained in Emcyt) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking estramustine:

Rare

  • Black, tarry stools
  • blood in urine or stools
  • cough or hoarseness
  • fever or chills
  • headaches (severe or sudden)
  • loss of coordination (sudden)
  • lower back or side pain
  • painful or difficult urination
  • pains in chest, groin, or leg (especially calf of leg)
  • pinpoint red spots on skin
  • shortness of breath (sudden, for no apparent reason)
  • slurred speech (sudden)
  • unusual bleeding or bruising
  • vision changes (sudden)
  • weakness or numbness in arm or leg

Check with your doctor as soon as possible if any of the following side effects occur while taking estramustine:

More common

  • Swelling of feet or lower legs

Rare

  • Skin rash or fever
  • unusual tiredness or weakness

Some side effects of estramustine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Breast tenderness or enlargement
  • decreased interest in sex
  • diarrhea
  • nausea

Less common

  • Trouble in sleeping
  • vomiting

For Healthcare Professionals

Applies to estramustine: oral capsule

Endocrine

Very common (10% or more): Breast tenderness (66%), breast enlargement (60%), gynecomastia

Frequency not reported: Erectile dysfunction

Hepatic

Very common (10% or more): Abnormal LDH and/or AST (31%), abnormal hepatic function

Common (1% to 10%): Abnormal bilirubin

Other

Very common (10% or more): Edema (19%)

Common (1% to 10%): Chest pain

Frequency not reported: Injection site thrombosis

Gastrointestinal

Very common (10% or more): Nausea (15%), diarrhea (12%), minor gastrointestinal upset (11%), vomiting

Common (1% to 10%): Flatulence, gastrointestinal bleeding

Respiratory

Very common (10% or more): Dyspnea (11%)

Common (1% to 10%): Pulmonary emboli, upper respiratory discharge, hoarseness, burning throat

Frequency not reported: Larynx edema

Cardiovascular

Very common (10% or more): Congestive heart failure

Common (1% to 10%): Myocardial infarction, thrombophlebitis

Frequency not reported: Myocardial ischemia, hypertension

Hematologic

Very common (10% or more): Anemia, leukopenia

Common (1% to 10%): Thrombocytopenia

Metabolic

Very common (10% or more): Fluid retention

Common (1% to 10%): Anorexia, thirst

Dermatologic

Common (1% to 10%): Pruritus, dry skin, rash, easy bruising, flushing, peeling skin on fingertip, thinning hair

Musculoskeletal

Common (1% to 10%): Leg cramps

Frequency not reported: Muscular weakness

Nervous system

Common (1% to 10%): Lethargy, cerebrovascular accident, headache

Ocular

Common (1% to 10%): Tearing of eyes

Psychiatric

Common (1% to 10%): Insomnia, emotional lability, anxiety

Frequency not reported: Confusional state, depression

Hypersensitivity

Frequency not reported: Hypersensitivity reactions, allergic reactions, angioedema, allergic dermatitis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Emcyt (www.drugs.com/mtm/emcyt.html).