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Note: This document contains side effect information about pimecrolimus topical. Some of the dosage forms listed on this page may not apply to the brand name Elidel.
In SummaryCommon side effects of Elidel include: application site reaction and localized burning. Other side effects include: local irritation and local pruritus. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to pimecrolimus topical: topical cream
Topical route (Cream)
Long-term safety of topical calcineurin inhibitors has not been established, and rare cases of malignancy (eg, skin and lymphoma) have been reported in patients treated with topical calcineurin inhibitors including pimecrolimus. Avoid continuous long-term use in any age group and apply to limited areas affected by atopic dermatitis. Not indicated for use in children less than 2 years of age.
Along with its needed effects, pimecrolimus topical (the active ingredient contained in Elidel) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking pimecrolimus topical:
More common
Less common
Incidence not known
Some side effects of pimecrolimus topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Incidence not known
For Healthcare Professionals
Applies to pimecrolimus topical: topical cream
DermatologicCommon (1% to 10%): Folliculitis, acne
Uncommon (0.1% to 1%): Furuncle, impetigo, herpes simplex, herpes zoster, skin papilloma, molluscum contagiosum, urticaria
Rare (less than 0.1%): Rash, angioedema, skin discoloration (e.g., hypopigmentation, hyperpigmentation)
GastrointestinalCommon (1% to 10%): Gastroenteritis, sore throat, diarrhea, nausea
Uncommon (0.1% to 1%): Tonsillitis, upper abdominal pain, vomiting, toothache
GenitourinaryCommon (1% to 10%): Dysmenorrhea
HypersensitivityVery rare (less than 0.01%): Anaphylaxis
ImmunologicCommon (1% to 10%): Influenza
Uncommon (0.1% to 1%): Molluscum contagiosum, staphylococcal infection, chickenpox
LocalVery common (10% or more): Application site burning (26%), application site reactions (i.e., irritation, pruritus erythema) (14.6%)
Common (1% to 10%): Application site irritation
Uncommon (0.1% to 1%): Application site disorders (i.e., rash, pain, paresthesia, desquamation, dryness, edema)
MusculoskeletalCommon (1% to 10%): Back pain, arthralgia
Nervous systemCommon (1% to 10%): Headache
MetabolicRare (less than 0.1%): Alcohol intolerance (in most cases, flushing, rash, burning, itching, or swelling occurred shortly after the intake of alcohol)
OncologicPostmarketing reports: Cutaneous and other types of lymphoma, skin cancers
OtherCommon (1% to 10%): Pyrexia
Uncommon (0.1% to 1%): Ear infection, otitis media
OcularCommon (1% to 10%): Conjunctivitis
Uncommon (0.1% to 1%): Eye infection
RespiratoryCommon (1% to 10%): Influenza, nasopharyngitis, upper respiratory infection, cough, asthma, rhinitis, bronchitis
Uncommon (0.1% to 1%): Sinus congestion, pharyngitis, nasal congestion, tonsillitis, sinusitis, dyspnea, epistaxis, pneumonia, viral upper respiratory tract infection, pharyngolaryngeal pain
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Elidel (www.drugs.com/elidel.html).
August 4, 2022
August 4, 2022
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