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Generic Name: dutasteride (doo TAS ter ide)
Brand Name: Avodart
Dutasteride is used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Dutasteride helps improve urinary flow and may also reduce your need for prostate surgery later on.
dutasteride is for use in men only.
Dutasteride may also be used for purposes not listed in this medication guide.
Dutasteride should never be taken by a woman or a child.
Dutasteride can cause birth defects if a woman is exposed to it during pregnancy. Dutasteride capsules should not be handled by a woman who is pregnant or may become pregnant.
You should not use dutasteride if you are allergic to dutasteride or finasteride.
Dutasteride should never be taken by a woman or a child. Dutasteride can be absorbed through the skin, and women or children should not be permitted to handle dutasteride capsules.
Tell your doctor if you have ever had:
liver disease.
Using dutasteride may increase your risk of developing prostate cancer. Your doctor will test your prostate specific antigen (PSA) to check for cancer while you are using this medicine.
Dutasteride is not for use by women, and this medicine can cause birth defects if a woman is exposed to it during pregnancy. Dutasteride capsules should not be handled by a woman who is pregnant or who may become pregnant.
If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away.
Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using dutasteride.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take the medicine at the same time each day, with or without food.
Swallow the capsule whole and do not crush, chew, break, or open it.
It may take up to 6 months or longer before you receive the full benefit of taking dutasteride. Your doctor will determine how long to treat you with this medicine. Keep using the medication as directed.
You will need frequent medical tests.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Do not donate blood while taking dutasteride and for at least 6 months after your treatment ends. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride.
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Common side effects may include:
decreased libido (sex drive);
decreased amount of semen released during sex;
impotence (trouble getting or keeping an erection); or
breast tenderness or enlargement.
The sexual side effects of dutasteride may continue after you stop taking dutasteride. Talk to your doctor if you have concerns about these side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Benign Prostatic Hyperplasia:
0.5 mg orally once a day
Use: Treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to reduce the risk of acute urinary retention (AUR) and BPH-related surgery.
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Other drugs may affect dutasteride, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Further informationRemember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.
Source: Drugs.com Dutasteride (www.drugs.com/mtm/dutasteride.html).
Applies to dutasteride: oral capsule liquid filled
Along with its needed effects, dutasteride may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking dutasteride:
Rare
Incidence not known
Some side effects of dutasteride may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
For Healthcare Professionals
Applies to dutasteride: oral capsule
OtherCommon (1% to 10%): Impotence, decreased libido, ejaculation disorders, breast disorders
Postmarketing reports: Testicular pain and swelling
-Impotence, decreased libido, and ejaculation disorders may persist after treatment discontinuation; this drug's role in this persistence is unknown.
-Ejaculation disorders included anorgasmia, retrograde ejaculation, decreased semen volume, decreased orgasmic sensation, abnormal orgasm, delayed ejaculation, ejaculation failure, and premature ejaculation.
-Breast disorders include breast enlargement, gynecomastia, breast swelling, breast pain, breast tenderness, nipple pain, and nipple swelling.
OncologicCommon (1% to 10%): High-grade prostate cancer
Frequency not reported: Male breast cancer
CardiovascularUncommon (0.1% to 1%): Cardiac failure
DermatologicUncommon (0.1% to 1%): Alopecia (primarily body hair loss), hypertrichosis
Nervous systemUncommon (0.1% to 1%): Dizziness, nervous system disorders
HypersensitivityPostmarketing reports: Hypersensitivity reactions (e.g., rash, pruritus, urticaria, localized edema, serious skin reactions, angioedema)
PsychiatricPostmarketing reports: Depressed mood
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.
Source: Drugs.com Dutasteride (www.drugs.com/mtm/dutasteride.html).
February 3, 2021
February 24, 2021
February 1, 2021
February 8, 2021
January 30, 2021
August 31, 2020
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