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Docusate Sodium

Docusate sodium Prescription
Generic Name: docusate (oral/rectal) (DOK ue sate)
Brand Name: Colace, Diocto, Doc-Q-Lace, Docu, Doculase, Docusil, Docusoft S, DocuSol, Dulcolax Stool Softener, Enemeez Mini, Kao-Tin, Pedia-Lax Stool Softener, Phillips Stool Softener, Promolaxin, Silace, Surfak Stool Softener, Sur-Q-Lax, ...show all 53 brand names
Physician reviewed docusate (oral/rectal) (oral/rectal) patient information - includes docusate (oral/rectal) description, dosage and directions.
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Docusate Sodium Drug Information:

Docusate is a stool softener that makes bowel movements softer and easier to pass. Docusate is used to relieve occasional constipation (irregularity). There are many brands and forms of docusate available. Not all brands are listed on this leaflet. Docusate may also be used for purposes not listed in this medication guide. You should not use docusate if you also use Mineral Oil, unless your doctor tells you to. You should not use docusate if you are allergic to it. Ask a doctor or pharmacist if docusate is safe to use if you have: Learn more

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Docusate Sodium Side Effects

For the Consumer

Applies to docusate: oral capsule, oral liquid, oral syrup, oral tablet

Other dosage forms:

  • rectal enema
What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Stomach cramps.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to docusate: compounding powder, oral capsule, oral liquid, oral syrup, oral tablet, rectal enema


Gastrointestinal side effects have included gastrointestinal cramping. Reports of bitter taste and throat irritation have been reported with administration of primarily the syrup and liquid formulations.


Dermatologic side effects have included rash.


Metabolic side effects have included at least one case report of hypomagnesemia.

Metabolic abnormalities reported include hypomagnesemia in one woman who took docusate chronically throughout her pregnancy. Magnesium levels returned to normal following discontinuation of docusate.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Docusate Sodium (www.drugs.com/mtm/docusate-oral-rectal.html).