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    Dilt-xr

    Generic Name: Diltiazem Long-Acting Capsules (dil TYE a zem)
    Brand Name: Cardizem CD, Cartia XT, Dilt-XR, Diltia XT, Taztia XT, ...show all 6 brand names.
    Easy-to-read patient leaflet for Dilt-XR. Includes indications, proper use, special instructions, precautions, and possible side effects.

    Average Savings for diltiazem hcl er (generic): 41.36%
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    Drug Information:
    This is not a list of all drugs or health problems that interact with Dilt-XR (diltiazem long-acting capsules). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Dilt-XR (diltiazem long-acting capsules) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use Dilt-XR (diltiazem long-acting capsules) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

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    Dilt-XR

    Generic Name: Diltiazem Long-Acting Capsules (dil TYE a zem)
    Brand Name: Cardizem CD, Cartia XT, Dilt-XR, Diltia XT, Taztia XT, ...show all 6 brand names.
    Uses of Dilt-XR:
    • It is used to treat high blood pressure.
    • It is used to treat a type of long-term chest pain (stable angina) in some people.
    • It may be given to you for other reasons. Talk with the doctor.

    What do I need to tell my doctor BEFORE I take Dilt-XR?

    • If you have an allergy to diltiazem or any other part of Dilt-XR (diltiazem long-acting capsules).
    • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have certain types of abnormal heartbeats. There are many types of abnormal heartbeats with which Dilt-XR (diltiazem long-acting capsules) must not be used. Ask your doctor or pharmacist if you are not sure.
    • If you have low blood pressure.
    • If you have had a recent heart attack.
    • If you are taking ivabradine.
    • If you are taking rifampin.
    • If you are breast-feeding or plan to breast-feed.

    This is not a list of all drugs or health problems that interact with Dilt-XR (diltiazem long-acting capsules).

    Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Dilt-XR (diltiazem long-acting capsules) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

    What are some things I need to know or do while I take Dilt-XR?

    • Tell all of your health care providers that you take Dilt-XR (diltiazem long-acting capsules). This includes your doctors, nurses, pharmacists, and dentists.
    • Avoid driving and doing other tasks or actions that call for you to be alert until you see how Dilt-XR (diltiazem long-acting capsules) affects you.
    • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
    • Check blood pressure and heart rate as the doctor has told you. Talk with the doctor.
    • You may need to have an ECG checked before starting Dilt-XR (diltiazem long-acting capsules) and while taking it. Talk with your doctor.
    • If you are taking Dilt-XR (diltiazem long-acting capsules) and have high blood pressure, talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
    • If you drink grapefruit juice or eat grapefruit often, talk with your doctor.
    • You may need to avoid drinking alcohol with some products. Talk with your doctor or pharmacist to see if you need to avoid drinking alcohol with Dilt-XR (diltiazem long-acting capsules).
    • If you are 65 or older, use Dilt-XR (diltiazem long-acting capsules) with care. You could have more side effects.
    • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Dilt-XR (diltiazem long-acting capsules) while you are pregnant.

    How is this medicine (Dilt-XR) best taken?

    Use Dilt-XR (diltiazem long-acting capsules) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

    • Swallow whole. Do not chew, break, or crush.
    • Take Dilt-XR (diltiazem long-acting capsules) at the same time of day.
    • Keep taking Dilt-XR (diltiazem long-acting capsules) as you have been told by your doctor or other health care provider, even if you feel well.
    • Some drugs may need to be taken with food or on an empty stomach. For some drugs it does not matter. Check with your pharmacist about how to take Dilt-XR (diltiazem long-acting capsules).
    • Some products may be opened and sprinkled on a spoonful of applesauce. Some products must be swallowed whole. Check with your pharmacist to see if you can open this product.

    What do I do if I miss a dose?

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    What are some side effects that I need to call my doctor about right away?

    WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

    • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
    • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
    • Very bad dizziness or passing out.
    • Slow heartbeat.
    • An abnormal heartbeat that is new or worse.
    • Heart failure has gotten worse in some people taking Dilt-XR (diltiazem long-acting capsules). If you have heart failure, talk with your doctor. Call your doctor right away if you have shortness of breath, a big weight gain, or swelling in the arms or legs.
    • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

    What are some other side effects of Dilt-XR?

    All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

    • Headache.
    • Feeling dizzy, tired, or weak.

    These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

    You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

    If OVERDOSE is suspected:

    If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

    How do I store and/or throw out Dilt-XR?

    • Store at room temperature.
    • Protect from light.
    • Store in a dry place. Do not store in a bathroom.
    • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
    • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

    Consumer information use

    • If your symptoms or health problems do not get better or if they become worse, call your doctor.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
    • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Dilt-XR (diltiazem long-acting capsules), please talk with your doctor, nurse, pharmacist, or other health care provider.
    • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

    Medical Disclaimer

    More about Dilt-XR (diltiazem)

    • Side Effects
    • During Pregnancy or Breastfeeding
    • Dosage Information
    • Drug Interactions
    • Pricing & Coupons
    • En Español
    • 1 Review
    • Drug class: calcium channel blocking agents

    Consumer resources

    Other brands: Cardizem, Cartia XT, Cardizem CD, Tiazac, ... +6 more

    Professional resources

    • ... +1 more

    Related treatment guides

    • Angina Pectoris Prophylaxis
    • Heart Failure
    • High Blood Pressure

    Editorial References and Review

    Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

    Source: Drugs.com Dilt-xr (www.drugs.com/cdi/dilt-xr.html).

    Dilt-xr Side Effects

    Note: This document contains side effect information about diltiazem. Some of the dosage forms listed on this page may not apply to the brand name Dilt-XR.

    In Summary

    More frequent side effects include: dizziness, edema, asthenia, headache, and vasodilation. See below for a comprehensive list of adverse effects.

    For the Consumer

    Applies to diltiazem: oral capsule extended release, oral capsule extended release 12 hr, oral capsule extended release 24 hr, oral tablet, oral tablet extended release, oral tablet extended release 24 hr

    Other dosage forms:

    • intravenous powder for solution, intravenous solution

    Along with its needed effects, diltiazem (the active ingredient contained in Dilt-XR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur while taking diltiazem:

    More common

    • Body aches or pain
    • congestion
    • cough
    • dryness or soreness of the throat
    • fever
    • hoarseness
    • runny nose
    • tender or swollen glands in the neck
    • trouble swallowing
    • voice changes

    Less common

    • Chest pain or discomfort
    • chills
    • diarrhea
    • difficult or labored breathing
    • feeling faint, dizzy, or lightheaded
    • feeling of warmth or heat
    • flushing or redness of the skin, especially on the face and neck
    • general feeling of discomfort or illness
    • headache
    • joint pain
    • loss of appetite
    • muscle aches and pains
    • nausea
    • shivering
    • slow or irregular heartbeat
    • sweating
    • swelling of the hands, ankles, feet, or lower legs
    • tightness in the chest
    • trouble sleeping
    • unusual tiredness or weakness
    • vomiting

    Incidence not known

    • Blistering, peeling, or loosening of the skin
    • itching
    • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    • no heartbeat
    • red skin lesions, often with a purple center
    • red, irritated eyes
    • sores, ulcers, or white spots in the mouth or on the lips

    Some side effects of diltiazem may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common

    • Sneezing
    • stuffy nose

    Less common

    • Acid or sour stomach
    • belching
    • constipation
    • continuing ringing or buzzing or other unexplained noise in the ears
    • degenerative disease of the joint
    • difficulty with moving
    • hearing loss
    • heartburn
    • indigestion
    • lack or loss of strength
    • muscle aching or cramping
    • muscle pains or stiffness
    • pain or tenderness around the eyes and cheekbones
    • rash
    • stomach discomfort, upset, or pain
    • swollen joints

    Incidence not known

    • Hair loss or thinning of the hair

    For Healthcare Professionals

    Applies to diltiazem: compounding powder, intravenous powder for injection, intravenous solution, oral capsule extended release, oral tablet, oral tablet extended release

    General

    The most commonly reported side effects include edema, headache, and dizziness.

    Cardiovascular

    Very common (10% or more): Peripheral edema (up to 15%)

    Common (1% to 10%): Arrhythmia (junctional rhythm/isorhythmic dissociation), asymptomatic/symptomatic hypotension, atrioventricular (AV) block (first/second/third degree), bradycardia, bundle branch block, ECG abnormality, edema, extrasystole/ventricular extrasystole, flushing, lower limb edema, palpitations, vasodilation

    Uncommon (0.1% to 1%): Orthostatic hypotension

    Frequency not reported: Angina, asystole/cardiac arrest, atrial flutter, chest pain, development/aggravation of congestive heart failure, hypotension, sinoatrial block, sinus node dysfunction, sinus pause/arrest, vasculitis, ventricular arrhythmia, ventricular fibrillation, ventricular tachycardia/tachycardia

    Postmarketing reports: Myocardial infarction, vasodilation symptoms (flushing, lower limb edema, sweating)

    A patient with Prinzmetal's angina developed asystole after a single, 60 mg dose.

    Myocardial infarction was not readily distinguishable from the natural history of the disease.

    Vasodilatory events (e.g., peripheral edema, headache, flushing) are dose-related and may be more common in elderly patients.

    First degree AV block and sinus bradycardia occurred more frequently with higher doses.

    Other

    Common (1% to 10%): Asthenia, fatigue, flu syndrome, infection, malaise, pain

    Frequency not reported: Thirst, tinnitus

    Gastrointestinal

    Common (1% to 10%): Abdominal enlargement, constipation, dyspepsia, gastric pain, nausea

    Uncommon (0.1% to 1%): Diarrhea, vomiting

    Rare (0.01% to 0.1%): Dry mouth

    Frequency not reported: Gastrointestinal disorder, gingivitis, gingival hyperplasia

    Dermatologic

    Well-documented cases of rashes (as leukocytoclastic vasculitis) have been reported, but a definitive between these events and this drug have not been established.

    Lichenoid keratosis and hyperpigmentation occurred in skin exposed to the sun.

    Common (1% to 10%): Erythema, hot flushes, rash, urticaria

    Frequency not reported: Acute generalized exanthematous pustular dermatitis, desquamative erythema with/without fever exfoliative dermatitis, facial edema, hyperhidrosis/sweating, hyperpigmentation, leukocytoclastic vasculitis, petechiae, photosensitivity (lichenoid keratosis), pruritus, Steven-Johnson's syndrome

    Postmarketing reports: Allergic dermatitis, alopecia, angioneurotic edema, erythema multiforme, generalized dermatitis, musculocutaneous reactions, simple erythema, toxic epidermal necrolysis

    Respiratory

    Common (1% to 10%): Bronchitis, cough, increased cough, pharyngitis, sinus/nasal congestion

    Frequency not reported: Dyspnea, epistaxis

    Postmarketing reports: Asthma aggravation, bronchospasm

    Nervous system

    Common (1% to 10%): Dizziness, headache, lightheadedness

    Frequency not reported: Amnesia, dysgeusia, extrapyramidal syndrome/symptoms, gait abnormality, paresthesia, somnolence, syncope, tremor

    Dizziness occurred more frequently with higher doses.

    Musculoskeletal

    Common (1% to 10%): Myalgia

    Frequency not reported: Creatine phosphokinase (CPK) increase, muscle cramp, muscle pain, muscle weakness, myopathy, neck rigidity, osteoarticular pain

    Metabolic

    Common (1% to 10%): Gout

    Frequency not reported: Anorexia, hyperglycemia, hyperuricemia, mild elevation of alkaline phosphatase, mild elevation of lactate dehydrogenase, thirst, weight increase

    Genitourinary

    Common (1% to 10%): Impotence

    Frequency not reported: Albuminuria, crystalluria, nocturia, polyuria, sexual difficulties

    Ocular

    Common (1% to 10%): Conjunctivitis

    Frequency not reported: Amblyopia, eye irritation, periorbital edema, retinopathy

    Local

    Common (1% to 10%): Injection site reactions (e.g., itching, burning)

    Psychiatric

    Uncommon (0.1% to 1%): Insomnia, nervousness

    Frequency not reported: Abnormal dreams, depression, hallucinations, mood changes (including depression), personality change

    Hepatic

    There were rare cases of clinical hepatitis that were reversible with discontinuation of this drug.

    Uncommon (0.1% to 1%): Increased hepatic enzymes (ALT, AST)

    Frequency not reported: Clinical hepatitis/hepatitis

    Hematologic

    Frequency not reported: Eosinophilia, hemolytic anemia, increased bleeding time, leukopenia, lymphadenopathy, thrombocytopenia

    Postmarketing reports: Purpura

    Hypersensitivity

    Frequency not reported: Allergic reactions, angioedema (including facial/periorbital edema)

    Endocrine

    Frequency not reported: Gynecomastia

    Editorial References and Review

    Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

    Source: Drugs.com Dilt-xr (www.drugs.com/cdi/dilt-xr.html).

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