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Dicyclomine Hydrochloride

Dicyclomine hydrochloride Prescription
Generic Name: dicyclomine (dye SYE kloe meen)
Brand Name: Bentyl, Dibent, Dicyclocot
Physician reviewed dicyclomine patient information - includes dicyclomine description, dosage and directions.

Average Savings for dicyclomine hydrochloride (generic): 32.23%
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Dicyclomine Hydrochloride Drug Information:

Dicyclomine relieves spasms of the muscles in the stomach and intestines. Dicyclomine is used to treat functional bowel or irritable bowel syndrome. Dicyclomine may also be used for purposes not listed in this medication guide. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking Alcohol can increase certain side effects of dicyclomine. Avoid becoming overheated or dehydrated during exercise and in hot weather. Dicyclomine can decrease your sweating, which can lead to heat stroke in a hot environment. Learn more

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Dicyclomine Hydrochloride Side Effects

For the Consumer

Applies to dicyclomine: oral capsules and tablets, oral solution, parenteral injection

Side effects include:

Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued.

Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; although adverse effects occasionally may be obviated by a reduction in dosage, this also will likely eliminate potential therapeutic effects. If dosage of ≥80 mg daily cannnot be achieved because of intolerance, discontinue dicyclomine.

Dry mouth, dizziness, blurred vision, nausea, light-headedness (especially with the injectable form), drowsiness, weakness, nervousness.

For Healthcare Professionals

Applies to dicyclomine: compounding powder, intramuscular solution, oral capsule, oral syrup, oral tablet

General

-The most serious adverse reactions include cardiovascular and central nervous system symptoms.

-The most common adverse reactions are dizziness, dry mouth, vision blurred, nausea, somnolence, asthenia and nervousness, fever, tachycardia, agitation, and dry skin/mucous membranes.

Gastrointestinal

Very common (10% or more): Dry mouth (33%), nausea (14%)

Rare (less than 0.1%): Constipation, anorexia

Frequency not reported: Thirst, delayed gastric emptying time, reduced gastric acid secretion, gastroesophageal reflux

Postmarketing reports: Abdominal distension, abdominal pain, dyspepsia, constipation, dry mouth, nausea, vomiting

Nervous system

Very common (10% or more): Dizziness (40%)

Common (1% to 10%): Somnolence, nervousness

Rare (less than 0.1%): Sedation, headache

Postmarketing reports: Dizziness, headache, somnolence, syncope

Ocular

Very common (10% or more): Blurred vision (27%)

Frequency not reported: Follicular conjunctivitis, all muscarinic antagonists can precipitate glaucoma

Postmarketing reports: Cycloplegia, mydriasis, blurred vision

Other

Common (1% to 10%): Asthenia

Frequency not reported: Fatigue

Postmarketing reports: Malaise, fatigue

Dermatologic

Rare (less than 0.1%): Rash

Postmarketing reports: Allergic dermatitis, erythema, rash

Renal

Rare (less than 0.1%): Dysuria

Genitourinary

Frequency not reported: Urinary retention, impotence in male patients

Postmarketing reports: Suppressed lactation

Cardiovascular

Postmarketing reports: Palpitations, tachyarrhythmias, thrombosis, thrombophlebitis

Hypersensitivity

Postmarketing reports: Face edema, angioedema, anaphylactic shock

Local

Postmarketing reports: Local pain, edema, skin color change, reflex sympathetic dystrophy syndrome (caused by inadvertent IV injection)

Psychiatric

Postmarketing reports: Delirium or symptoms of delirium such as amnesia (or transient global amnesia), nervousness, agitation, confusional state, delusion, disorientation, hallucination (including visual hallucination), and mania, mood (altered and pseudodementia).

Respiratory

Postmarketing reports: Dyspnea, nasal congestion

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Dicyclomine Hydrochloride (www.drugs.com/mtm/dicyclomine.html).