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Daptacel

Generic Name: diphtheria, tetanus, acellular pertussis vaccine (DTaP) pediatric (dif THEER ee uh, TET a nus, ay SEL yoo ler per TUS iss)
Brand Names: Daptacel (DTaP), Infanrix (DTaP), Infanrix (DTaP) Preservative Free
Daptacel is a vaccine used to help prevent diphtheria, tetanus, and acellular pertussis. Learn about side effects, interactions and indications.
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Drug Information:
Daptacel is a combination vaccine that helps prevent diphtheria, tetanus, and pertussis. Diphtheria, tetanus, and pertussis are serious diseases caused by bacteria. Diphtheria causes a thick coating in the nose, throat, and airway. It can lead to breathing problems, paralysis, heart failure, and even death. Tetanus (lockjaw) causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw so the victim cannot open his mouth or swallow. Tetanus leads to death in about 1 out of 10 cases. Learn more

Daptacel Side Effects

Daptacel (DTaP) Side Effects

Note: This document contains side effect information about diphtheria and tetanus toxoids / pertussis, acellular. Some of the dosage forms listed on this page may not apply to the brand name Daptacel (DTaP).

For the Consumer

Applies to diphtheria and tetanus toxoids / pertussis, acellular: intramuscular suspension

Along with its needed effects, diphtheria and tetanus toxoids/pertussis, acellular may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking diphtheria and tetanus toxoids / pertussis, acellular:

Less common

  • Collapse or shock-like state
  • crying for 3 hours or more
  • fever over 102.2 °F
  • redness or swelling of 4 inches or more at the injection site
  • seizures (convulsions)
  • severe pain at the injection site

Incidence not known

  • Agitation
  • back pain
  • black, tarry stools
  • bleeding gums
  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • blood in the urine or stools
  • bloody nose
  • bluish color of the fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • confusion
  • cough
  • diarrhea
  • difficulty with swallowing
  • dizziness
  • drowsiness
  • fast heartbeat
  • hallucinations
  • headache
  • hoarseness
  • irritability
  • irritation
  • joint pain, stiffness, or swelling
  • loss of bladder control
  • loss of consciousness
  • loss of strength or energy
  • muscle pain or weakness
  • nausea and vomiting
  • pain or cramping in the abdomen or stomach
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rash with flat lesions or small raised lesions on the skin
  • screaming
  • shortness of breath
  • sleepiness or unusual drowsiness
  • sneezing
  • sore throat
  • stiff neck
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • tightness in the chest
  • total body jerking
  • unusual bleeding or bruising
  • unusual tiredness or weakness (sudden and severe)

Some side effects of diphtheria and tetanus toxoids / pertussis, acellular may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Fever of 99.5 °F or more
  • fussiness
  • loss of appetite
  • mild pain, redness, swelling, or tenderness at the injection site
  • restlessness
  • weight loss

Incidence not known

  • Crying
  • ear pain

For Healthcare Professionals

Applies to diphtheria and tetanus toxoids / pertussis, acellular: intramuscular suspension

Local

Local side effects have included erythema, swelling, tenderness, and pain.

Hypersensitivity

Hypersensitivity side effects have included rare reports of anaphylactic reactions (ie, hives, swelling of the mouth, difficulty breathing, hypotension, or shock). Arthus-type hypersensitivity reactions, characterized by severe local reactions (generally starting 2 to 8 hours after an injection), may follow receipt of tetanus toxoid.

General

General side effects have included fever greater than 101 degrees F (rectal), high-pitched cry, persistent cry, and irritability.

Gastrointestinal

Gastrointestinal side effects have included anorexia and vomiting.

Nervous system

Nervous system side effects have included drowsiness. A review by the Institute of Medicine (IOM) found evidence for a causal relationship between tetanus toxoid and both brachial neuritis and Guillain-Barre syndrome.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Daptacel (www.drugs.com/daptacel.html).