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Cyclobenzaprine hcl

Generic Name: cyclobenzaprine (sye kloe BEN za preen)
Brand Names: Amrix, Comfort Pac with Cyclobenzaprine, Fexmid, Flexeril
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes cyclobenzaprine side effects, interactions and indications.
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Drug Information:
Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Cyclobenzaprine is used together with rest and physical Therapy to treat skeletal muscle conditions such as pain or injury. Cyclobenzaprine may also be used for purposes not listed in this medication guide. You should not use cyclobenzaprine if you have an allergy to the medication, a certain type of Thyroid disorder (hyperThyroidism), heart block, congestive heart failure, a heart rhythm disorder, or you have recently had a heart attack. Learn more

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Cyclobenzaprine hcl Side Effects

For the Consumer

Applies to cyclobenzaprine: oral capsule extended release, oral suspension, oral tablet

Along with its needed effects, cyclobenzaprine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cyclobenzaprine:

Rare

  • Clumsiness or unsteadiness
  • confusion
  • fainting
  • mental depression
  • problems in urinating
  • ringing or buzzing in the ears
  • skin rash, hives, or itching occurring without other symptoms of an allergic reaction listed above
  • unusual thoughts or dreams
  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking cyclobenzaprine:

Symptoms of overdose

  • Convulsions (seizures)
  • drowsiness (severe)
  • dry, hot, flushed skin
  • fast or irregular heartbeat
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • increase or decrease in body temperature
  • troubled breathing
  • unexplained muscle stiffness
  • unusual nervousness or restlessness (severe)
  • vomiting (occurring together with other symptoms of overdose)

Some side effects of cyclobenzaprine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Blurred vision
  • dizziness, drowsiness, or lightheadedness
  • dryness of the mouth

Less common or rare

  • Bloated feeling or gas, indigestion, nausea or vomiting, or stomach cramps or pain
  • constipation
  • diarrhea
  • excitement or nervousness
  • frequent urination
  • general feeling of discomfort or illness
  • headache
  • muscle twitching
  • numbness, tingling, pain, or weakness in hands or feet
  • pounding heartbeat
  • problems in speaking
  • trembling
  • trouble sleeping
  • unpleasant taste or other taste changes
  • unusual muscle weakness
  • unusual tiredness

For Healthcare Professionals

Applies to cyclobenzaprine: compounding powder, oral capsule extended release, oral tablet, oral and topical kit

General

The most frequently occurring adverse reactions have included dry mouth, dizziness, fatigue, constipation, nausea, dyspepsia, and somnolence.

Nervous system

Very common (10% or more): Drowsiness (up to 38%)

Common (1% to 10%): Dizziness, somnolence

Postmarketing reports: Headache, serotonin syndrome, seizures, ataxia, tremors, hypertonia, convulsions, abnormal sensations, paresthesia, ageusia

Elderly patients may be particularly susceptible to the sedation and confusion which may accompany cyclobenzaprine therapy.

Psychiatric

Common (1% to 10%): Irritability, mental acuity decreased, nervousness

Postmarketing reports: Nervousness, confusion, disorientation, insomnia, depressed mood, anxiety, agitation, psychosis, abnormal thinking and dreaming, hallucinations, excitement

Hypersensitivity

Postmarketing reports: Anaphylaxis, angioedema, pruritus, facial edema, urticaria, rash

Gastrointestinal

Very common (10% or more): Dry mouth (up to 32%)

Common (1% to 10%): Constipation, nausea, dyspepsia, abdominal pain, acid regurgitation, diarrhea

Postmarketing reports: Unpleasant taste, vomiting, anorexia, gastritis, thirst, flatulence, tongue edema

Hepatic

Postmarketing reports: Abnormal liver function, hepatitis, jaundice, cholestasis

Cardiovascular

Postmarketing reports: Syncope, tachycardia, arrhythmia, vasodilation, palpitation, hypotension

Other

Common (1% to 10%): Fatigue

Postmarketing reports: Asthenia, malaise, vertigo

Dermatologic

Postmarketing reports: Sweating

Genitourinary

Postmarketing reports: Urinary frequency and/or retention

Musculoskeletal

Postmarketing reports: Local weakness, dysarthria, muscle twitching

Ocular

Postmarketing reports: Blurred vision, diplopia, tinnitus

Respiratory

Common (1% to 10%): Upper respiratory infection, pharyngitis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Cyclobenzaprine Hcl (www.drugs.com/cyclobenzaprine.html).