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    Colchicine

    Fact Checked
    Health Integrity
    Colchicine Prescription
    Generic Name: Colchicine Tablets (KOL chi seen)
    Brand Name: Colcrys
    Easy-to-read patient leaflet for Colchicine Tablets. Includes indications, proper use, special instructions, precautions, and possible side effects.

    Average Savings for colchicine (brand): 13.6%
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    Colchicine Drug Information:

    This is not a list of all drugs or health problems that interact with this medicine (colchicine tablets). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (colchicine tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use this medicine (colchicine tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

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    Colchicine Medicare Coverage

    Colchicine Medicare Overview

    Does Medicare cover Colchicine?

    No

    56% of Medicare Part D and Medicare Advantage plans cover this drug, so it's pretty much a toss-up.
    How much is my Colchicine co-pay with Medicare?

    It depends. Which coverage stage are you in? Click on a tab below…

    CO-PAY RANGE

    $8 – $202

    In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

    Ways to Save on Colchicine

    Here are some ways that may lower the cost of your colchicine prescription.

    • Instead of Medicare, Use a USA Rx Coupon

      If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

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    Colchicine Tablets

    Generic Name: Colchicine Tablets (KOL chi seen)
    Brand Name: Colcrys
    Uses of Colchicine Tablets:
    • It is used to treat gout attacks.
    • It is used to prevent gout attacks.
    • It is used to treat familial Mediterranean fever.
    • It may be given to you for other reasons. Talk with the doctor.

    What do I need to tell my doctor BEFORE I take Colchicine Tablets?

    • If you have an allergy to colchicine or any other part of this medicine (colchicine tablets).
    • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Kidney disease or liver disease.

    This is not a list of all drugs or health problems that interact with this medicine (colchicine tablets).

    Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (colchicine tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

    What are some things I need to know or do while I take Colchicine Tablets?

    • Tell all of your health care providers that you take this medicine (colchicine tablets). This includes your doctors, nurses, pharmacists, and dentists.
    • This medicine interacts with many other drugs. The chance of side effects may be raised. This may include severe, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take this medicine (colchicine tablets) with all of your other drugs (prescription or OTC, natural products, vitamins).
    • Avoid grapefruit and grapefruit juice.
    • Deadly overdoses have happened with this medicine (colchicine tablets) in adults and children. Keep away from children. Do not take more than you were told. If this drug is taken by accident, call your poison control center or get medical care right away.
    • Some males have had sperm problems while taking this medicine (colchicine tablets). This may affect being able to father a child. This may go back to normal after the drug is stopped. Talk with the doctor.
    • If you are 65 or older, use this medicine (colchicine tablets) with care. You could have more side effects.
    • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

    How is this medicine (Colchicine Tablets) best taken?

    Use this medicine (colchicine tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

    • Take with or without food.

    What do I do if I miss a dose?

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • To treat a gout attack, this medicine (colchicine tablets) is taken on an as needed basis.

    What are some side effects that I need to call my doctor about right away?

    WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

    • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
    • Numbness or tingling in the hands or feet.
    • Pale skin.
    • Very bad muscle problems have happened with this medicine (colchicine tablets). This can also lead to kidney problems. Tell your doctor if you have muscle pain or weakness, especially if you feel very tired or weak or have a fever. Tell your doctor if you are not able to pass urine or you have a change in how much urine is passed.
    • Low blood cell counts have happened with this medicine (colchicine tablets). If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Call your doctor right away if you have signs of infection like fever, chills, or sore throat; any unexplained bruising or bleeding; or if you feel very tired or weak.

    What are some other side effects of Colchicine Tablets?

    All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

    • Stomach pain.
    • Diarrhea.
    • Upset stomach or throwing up.

    These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

    You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

    If OVERDOSE is suspected:

    If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

    How do I store and/or throw out Colchicine Tablets?

    • Store at room temperature.
    • Keep lid tightly closed.
    • Store in a dry place. Do not store in a bathroom.
    • Protect from light.
    • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
    • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

    Consumer information use

    • If your symptoms or health problems do not get better or if they become worse, call your doctor.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
    • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (colchicine tablets) is refilled. If you have any questions about this medicine (colchicine tablets), please talk with the doctor, pharmacist, or other health care provider.
    • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

    Medical Disclaimer

    More about colchicine

    • Side Effects
    • During Pregnancy or Breastfeeding
    • Dosage Information
    • Patient Tips
    • Drug Images
    • Drug Interactions
    • Compare Alternatives
    • Support Group
    • Pricing & Coupons
    • En Español
    • 78 Reviews
    • Drug class: antigout agents
    • FDA Alerts (3)

    Consumer resources

    • Colchicine
    • Colchicine Capsules

    Other brands: Colcrys, Mitigare

    Professional resources

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    Editorial References and Review

    Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

    Source: Drugs.com Colchicine (www.drugs.com/colchicine.html).

    Colchicine Side Effects

    In Summary

    Commonly reported side effects of colchicine include: diarrhea and nausea. See below for a comprehensive list of adverse effects.

    For the Consumer

    Applies to colchicine: oral capsule, oral tablet

    Along with its needed effects, colchicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur while taking colchicine:

    More common

    • Diarrhea
    • nausea or vomiting
    • stomach pain

    Rare

    • Black, tarry stools
    • blood in the urine or stools
    • burning, "crawling", or tingling feeling in the skin
    • difficulty with breathing when exercising
    • fever with or without chills
    • headache
    • large, hive-like swellings on the face, eyelids, mouth, lips, or tongue
    • muscle weakness
    • numbness in the fingers or toes (usually mild)
    • pain
    • peeling of the skin
    • pinpoint red spots on the skin
    • redness
    • skin rash or hives
    • sores, ulcers, or white spots on the lips or in the mouth
    • sore throat
    • swelling
    • tenderness
    • unusual bleeding or bruising
    • unusual tiredness or weakness

    Get emergency help immediately if any of the following symptoms of overdose occur while taking colchicine:

    Symptoms of overdose

    • Bleeding
    • burning feeling in the stomach, throat, or skin
    • convulsions (seizures)
    • diarrhea (severe or bloody)
    • fast, shallow breathing
    • muscle weakness (very severe)
    • nausea, stomach pain, or vomiting (severe)

    Some side effects of colchicine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    Less common

    • Hair loss
    • loss of appetite

    For Healthcare Professionals

    Applies to colchicine: compounding powder, intravenous solution, oral capsule, oral tablet

    General

    The most common adverse reactions have included gastrointestinal symptoms and pharyngolaryngeal pain.

    Gastrointestinal

    Very common (10% or more): Diarrhea (23%)

    Common (1% to 10%): Abdominal cramping, abdominal pain, nausea, vomiting

    Frequency not reported: Lactose intolerance, gastrointestinal hemorrhage, paralytic ileus, stomatitis

    Gastrointestinal events including diarrhea, nausea, vomiting, and abdominal pain are the most common adverse reactions reported with use of this drug. These events are often the first signs of toxicity and may indicate the need for dose reduction or therapy discontinuation.

    Hematologic

    Rare (less than 0.1%): Agranulocytosis, thrombocytopenia, aplastic anemia

    Postmarketing reports: Myelosuppression, disseminated intravascular coagulation

    Nervous system

    Rare (less than 0.1%): Peripheral neuritis

    Frequency not reported: Sensory motor neuropathy

    Musculoskeletal

    Rare (less than 0.1%): Myopathy, rhabdomyolysis

    Frequency not reported: Elevated CPK, myotonia, muscle weakness, muscle pain

    Hypersensitivity

    Very rare (less than 0.01%): Hypersensitivity including angioedema

    Renal

    Frequency not reported: Renal damage, bladder spasm, anuria, oliguria

    Hepatic

    Frequency not reported: elevated AST, elevated ALT, elevated alkaline phosphatase, hepatic damage

    Respiratory

    Common (1% to 10%): Pharyngolaryngeal pain

    Postmarketing reports: Adult respiratory distress syndrome

    Ocular

    There have been reports of corneal ulcers refractory to conventional treatment and delayed corneal wound healing following strabismus surgery in patients receiving colchicine. Discontinuation of colchicine therapy resulted in satisfactory wound healing within several days.

    Frequency not reported: Delayed corneal wound healing

    Dermatologic

    Rare (less than 0.1%): Alopecia

    Very rare (less than 0.01%): Nonthrombocytopenic purpura rashes, rashes, urticaria, dermatoses, dermatitis

    Frequency not reported: Maculopapular rash

    Endocrine

    Frequency not reported: Hypothyroidism

    Genitourinary

    Rare (less than 0.1%): Azoospermia, oligospermia

    Frequency not reported: Amenorrhea, dysmenorrhea, hematuria

    Metabolic

    Frequency not reported: Loss of appetite

    Editorial References and Review

    Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

    Source: Drugs.com Colchicine (www.drugs.com/colchicine.html).

    Latest News for Colchicine