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Clotrimazole is an antifungal medication. It is like an antibiotic but is used to treat yeast (fungal) infections.
Oral clotrimazole is used to treat and prevent yeast infections of the mouth and throat.
Clotrimazole may also be used for purposes other than those listed in this medication guide.
Take all of the clotrimazole that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.
Before taking this medication, tell your doctor if you have liver disease. You may not be able to take clotrimazole, or you may need a lower dose or special monitoring during treatment.
Clotrimazole is not absorbed through your stomach. It will not treat fungal infections in any part of your body other than your mouth and throat. Talk to your doctor if you have another type of fungal infection such as athlete's foot, jock itch, ringworm, or a vaginal yeast infection.
Oral clotrimazole is in the FDA pregnancy category C. This means that it is not known whether clotrimazole will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
It is not known whether clotrimazole will harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
The safety and effectiveness of clotrimazole have not been established for children younger than 3 years of age.
Take clotrimazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
The troches should be allowed to dissolve slowly in your mouth. Suck on one troche at a time until it is completely dissolved, usually 30 minutes.
Do not chew or swallow the troches whole.
The troches are usually used five times a day. Follow your doctor's instructions.
Store clotrimazole at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
Seek emergency medical attention.
Symptoms of a clotrimazole overdose are unknown.
There are no restrictions on foods, beverages, or activities during treatment with clotrimazole unless your doctor directs otherwise.
Stop taking clotrimazole and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
Side effects are not likely to occur with clotrimazole. Continue to take clotrimazole and talk to your doctor if you experience
nausea or stomach upset,
vomiting,
itching, or
an unpleasant sensation in the mouth.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Oral Thrush:
Treatment: 10 mg orally 5 times a day for 14 days
Prophylaxis: 10 mg orally 3 times a day for the duration of chemotherapy OR until steroids are reduced to maintenance levels
Comment:
-Safety and efficacy of treatment doses given for a prolonged duration have not been established. Treatment should be limited to short-term use when possible.
Uses:
-Local treatment of oropharyngeal candidiasis that has been confirmed by a KOH smear of other culture before treatment.
-Prophylaxis to reduce the incidence of oropharyngeal candidiasis in patients who are immunocompromised (e.g., chemotherapy, radiotherapy, steroid therapy in the treatment of leukemia, solid tumors, or renal transplantation)
Usual Pediatric Dose for Oral Thrush:
3 years and older:
Treatment: 10 mg orally 5 times a day for 14 days
Prophylaxis: 10 mg orally 3 times a day for the duration of chemotherapy OR until steroids are reduced to maintenance levels
Comment:
-Safety and efficacy of treatment doses given for a prolonged duration have not been established. Treatment should be limited to short-term use when possible.
Uses:
-Local treatment of oropharyngeal candidiasis that has been confirmed by a KOH smear of other culture before treatment.
-Prophylaxis to reduce the incidence of oropharyngeal candidiasis in patients who are immunocompromised (e.g., chemotherapy, radiotherapy, steroid therapy in the treatment of leukemia, solid tumors, or renal transplantation)
Since clotrimazole is not absorbed by your body, drug interactions are not expected. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Clotrimazole (www.drugs.com/mtm/clotrimazole.html).
Commonly reported side effects of clotrimazole include: increased serum aspartate aminotransferase. See below for a comprehensive list of adverse effects.
Applies to clotrimazole: lozenge/troche
Along with its needed effects, clotrimazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Some side effects of clotrimazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Note: Some of the side effects, such as abdominal or stomach cramping or pain or diarrhea, usually occur only when the medicine is swallowed
Applies to clotrimazole: oral lozenge, topical cream, topical lotion, topical powder, topical solution, vaginal cream with applicator, vaginal kit, vaginal tablet
Very common (10% or more): AST elevation (up to 15%)
Frequency not reported: Abnormal liver function tests
Frequency not reported: Nausea, vomiting, unpleasant mouth sensations
Frequency not reported: Pruritus
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Clotrimazole (www.drugs.com/mtm/clotrimazole.html).
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