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Clobex Prescription
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Generic Name: clobetasol topical (kloe BAY ta sol)
Brand Name: Clobex, Clodan, Impoyz, Olux, Olux-e, Temovate, Tovet
Physician reviewed Clobex patient information - includes Clobex description, dosage and directions. Average Savings for clobetasol propionate (generic): 34.31%
Generic Name: clobetasol topical (kloe BAY ta sol)
Brand Name: Clobex, Clodan, Impoyz, Olux, Olux-e, Temovate, Tovet
Physician reviewed Clobex patient information - includes Clobex description, dosage and directions. Average Savings for clobetasol propionate (generic): 34.31%
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1 tablets of Clobex 40 mg
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Clobex Drug Information:

Clobetasol is a highly potent steroid that helps reduce inflammation in the body. Clobex (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication. Clobex may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare prOviders about all your medical conditions, allergies, and all medicines you use. You should not use Clobex if you are allergic to it. Learn more

Clobex Side Effects

Note: This document contains side effect information about clobetasol topical. Some of the dosage forms listed on this page may not apply to the brand name Clobex.

For the Consumer

Applies to clobetasol topical: topical application cream, topical application emollient cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment, topical application shampoo, topical application solution, topical application spray

Along with its needed effects, clobetasol topical (the active ingredient contained in Clobex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking clobetasol topical:

More common

  • Burning or stinging at the application site

Less common

  • Burning sensation of the skin
  • dry skin
  • flushing or redness of the skin
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • skin irritation
  • skin rash, encrusted, scaly and oozing
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)


  • Thinning, weakness, or wasting away of the skin

Incidence not known

  • Burning, itching, and pain in hairy areas, or pus at the root of the hair
  • hair loss
  • hives
  • redness and scaling around the mouth
  • thinning of the hair

Some side effects of clobetasol topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Cough
  • sore throat

Less common

  • Body aches or pain
  • changes in skin coloring
  • congestion
  • dryness of the throat
  • headache
  • raised, dark red, wart-like spots on the skin, especially when used on the face
  • skin discomfort
  • stuffy or runny nose
  • tender, swollen glands in the neck
  • trouble swallowing
  • unusual tiredness or weakness
  • voice changes

Incidence not known

  • Acne or pimples
  • burning and itching of the skin with pinhead-sized red blisters
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of treated areas of dark skin
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • softening of the skin

For Healthcare Professionals

Applies to clobetasol topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment, topical shampoo, topical solution, topical spray


The most common side effect reported was skin discomfort.


Postmarketing reports: Cushing's syndrome, adrenal suppression


Common (1% to 10%): Skin discomfort, acne/folliculitis, telangiectasia, skin atrophy, dry skin

Uncommon (0.1% to 1%): Local signs of irritation, pruritus, urticaria

Frequency not reported: Stria, purpura, contact dermatitis, pigmentation changes, pustular eruptions, hypertrichosis, irritant dermatitis

Postmarketing reports: Erythema, alopecia, pain of skin, skin exfoliation, chapped skin, scaling, induration/papulation,

lichenification, psoriasis (aggravation) plaque elevation, excoriation, rash, hair color changes, skin tightness


Frequency not reported: Itching


Common (1% to 10%): Eye stinging/burning

Postmarketing reports: Eye pain, blurred vision, eye irritation


Frequency not reported: Edema


Postmarketing reports: Nausea


Frequency not reported: Hyperglycemia, glucosuria

Nervous system

Common (1% to 10%): Headache

Postmarketing reports: Dizziness

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Clobex (www.drugs.com/mtm/clobex.html).