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Ciprodex Prescription
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Generic Name: ciprofloxacin and dexamethasone otic (SIP roe FLOX a sin and DEX a METH a sone OH tik)
Brand Names: Ciprodex
Ciprodex (ciprofloxacin and dexamethasone) is used to treat ear infections. Includes Ciprodex side effects, interactions and indications.
Generic Name: ciprofloxacin and dexamethasone otic (SIP roe FLOX a sin and DEX a METH a sone OH tik)
Brand Names: Ciprodex
Ciprodex (ciprofloxacin and dexamethasone) is used to treat ear infections. Includes Ciprodex side effects, interactions and indications.
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1 tablets of Ciprodex 40 mg
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Ciprodex Drug Information:

Ciprodex ear drops contain Ciprofloxacin and Dexamethasone. Ciprofloxacin is an antibiotic that treats infections caused by bacteria. Dexamethasone is a steroid. It reduces the actions of chemicals in the body that cause inflammation. Ciprodex is used to treat infections inside the ear (also called otitis media), and infections of the ear canal (also called otitis externa). Ciprodex may also be used for purposes not listed in this medication guide. You should not use Ciprodex ear drops if you have a viral infection affecting your ear canal, including herpes or chickenpox. Learn more

Ciprodex Medicare Coverage

Ciprodex Medicare Overview

Does Medicare cover Ciprodex?


93% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Ciprodex co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…


$42 – $286

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Ciprodex

Here are some ways that may lower the cost of your ciprodex prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Ciprodex Side Effects

Note: This document contains side effect information about ciprofloxacin / dexamethasone otic. Some of the dosage forms listed on this page may not apply to the brand name Ciprodex.

For the Consumer

Applies to ciprofloxacin/dexamethasone otic: otic suspension

Along with its needed effects, ciprofloxacin/dexamethasone otic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ciprofloxacin / dexamethasone otic:

Incidence not known

  • Cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • tightness in the chest
  • unusual tiredness or weakness

Some side effects of ciprofloxacin / dexamethasone otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Ear discomfort
  • ear pain
  • itching skin on the ear


  • Bitter, sour, or unusual taste in the mouth
  • ear congestion
  • ear debris
  • ear residue
  • redness of the skin
  • superimposed ear infection (second ear infection)

For Healthcare Professionals

Applies to ciprofloxacin / dexamethasone otic: otic suspension


The most commonly reported side effects in patients with tympanostomy tubes and acute otitis media were ear pain, discomfort, and dysgeusia/tasting medicine.

The most commonly reported side effect in patients with acute otitis externa was ear pruritus.


Common (1% to 10%): Ear discomfort, ear pain, ear pruritus

Uncommon (0.1% to 1%): Otorrhea, fatigue, ear congestion, candidiasis/fungal ear infection, crying, superimposed ear infection, device/tympanostomy tube blockage/occlusion, ear precipitate/residue/debris/medication residue present

Rare (0.01% to 0.1%): Hypoacusis, tinnitus

Frequency not reported: decreased hearing, ear disorder

Postmarketing reports: Auricular swelling

Nervous system

Uncommon (0.1% to 1%): Taste perversion/dysgeusia, paresthesia/tingling in ears

Rare (0.01% to 0.1%): Dizziness, headache


Uncommon (0.1% to 1%): Erythema, flushing

Rare (0.01% to 0.1%): Rash erythematous

Postmarketing reports: Skin exfoliation


Uncommon (0.1% to 1%): Vomiting

Frequency not reported: Oral moniliasis


Uncommon (0.1% to 1%): Irritability


Postmarketing reports: Hypersensitivity

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

Source: Drugs.com Ciprodex (www.drugs.com/ciprodex.html).