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Cetirizine Hydrochloride

Cetirizine hydrochloride Prescription
Generic Name: cetirizine (se TIR a zeen)
Brand Names: Zyrtec
Cetirizine treats cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose. Includes cetirizine side effects, interactions and indications.

Average Savings for cetirizine hydrochloride (generic): 46.51%
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Cetirizine Hydrochloride Drug Information:

Cetirizine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. It is used to treat cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose. Cetirizine is also used to treat itching and swelling caused by hives. Cetirizine may also be used for other purposes not listed in this medication guide. Before taking cetirizine, tell your doctor about all of your medical conditions. Learn more

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Cetirizine Hydrochloride Side Effects

In Summary

More frequently reported side effects include: abdominal pain, drowsiness, and fatigue. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to cetirizine: oral solution, oral tablets and chewable tablets

Side effects include:

Adults and children ≥12 years of age: Somnolence, fatigue, dry mouth. Insomnia reported with cetirizine hydrochloride-pseudoephedrine hydrochloride fixed combination.

Children 2–11 years of age: Headache, pharyngitis, abdominal pain.

Children 6 months to 2 years of age: Irritability, fussiness, insomnia, fatigue, malaise.

For Healthcare Professionals

Applies to cetirizine: oral capsule, oral liquid, oral syrup, oral tablet, oral tablet chewable, oral tablet dispersible

General

The most commonly reported side effects include somnolence, dizziness, and headache.

Nervous system

Very common (10% or more): Somnolence (up to 14.3%), headache (up to 14%)

Common (1% to 10%): Dizziness

Frequency not reported: Altered sense of taste, paresthesia, hypertonia, tremor, abnormal coordination/incoordination, ataxia, hyperesthesia, hyperkinesia, hypoesthesia, migraine, paralysis, twitching, parosmia, taste loss/perversion

Postmarketing reports: Convulsions, dysgeusia, dyskinesia, dystonia, syncope, amnesia, vertigo, memory impairment

Gastrointestinal

Common (1% to 10%): Dry mouth, nausea, diarrhea, vomiting, abdominal pain

Uncommon (0.1% to 1%): Dyspepsia

Frequency not reported: Tongue disorder, constipation, flatulence, increased salivation, aggravated tooth caries, eructation, gastritis, hemorrhoids, melena, rectal hemorrhage, stomatitis/ulcerative stomatitis, tongue discoloration/edema, enlarged abdomen

Respiratory

Common (1% to 10%): Pharyngitis, rhinitis, coughing, epistaxis

Frequency not reported: Dyspnea, respiratory disorder, bronchospasm, upper respiratory tract infection, dysphonia, bronchitis, hyperventilation, increased sputum, pneumonia, sinusitis, nasal polyp

Other

Common (1% to 10%): Fatigue

Frequency not reported: Earache, tinnitus, fever, pain, rigor, thirst, deafness, ototoxicity, accidental injury, face edema, leg edema, malaise

Postmarketing reports: Asthenia, stillbirth

Psychiatric

Common (1% to 10%): Insomnia

Frequency not reported: Nervousness, impaired concentration, confusion, decreased libido, abnormal thinking, anxiety, depersonalization, emotional lability, euphoria, paroniria, sleep disorder

Postmarketing reports: Agitation, aggression/aggressive reaction, depression, hallucination, tic, suicidal ideation/suicide

Musculoskeletal

Very rare (less than 0.01%): Myelitis

Frequency not reported: Back pain, myalgia, arthralgia, bone disorder/fracture, leg cramps, arthritis, arthrosis, muscle weakness

Dermatologic

Frequency not reported: Pruritus/intense itching, increased sweating, acne, alopecia, bullous eruption, dermatitis, dry skin, eczema, erythematous rash, furunculosis, hyperkeratosis, hypertrichosis, maculopapular rash, photosensitivity/photosensitivity toxic reaction, purpura, seborrhea, skin disorder/nodule

Postmarketing reports: Rash, urticaria, angioneurotic edema, fixed drug eruption, acute generalized exanthematous pustulosis (AGEP)

Ocular

Frequency not reported: Eye abnormality, periorbital edema, abnormal vision, eye pain, conjunctivitis, ptosis, visual field defects, blindness, glaucoma, ocular hemorrhage, xerophthalmia, periorbital edema/eye swelling

Postmarketing reports: Accommodation disorder/loss of accommodation, blurred vision, oculogyration, orofacial dyskinesia

Genitourinary

Frequency not reported: Polyuria, urinary retention, urinary tract infection, dysmenorrhea, hematuria, micturition frequency, urinary incontinence, female breast pain, intermenstrual bleeding, leukorrhea, menorrhagia, vaginitis

Postmarketing reports: Dysuria, enuresis

Cardiovascular

Frequency not reported: Flushing, palpitations, tachycardia, edema/general edema, chest pain, cardiac failure, hypertension, hot flashes, peripheral edema, pallor

Postmarketing reports: Severe hypotension

Metabolic

Frequency not reported: Increased appetite, anorexia, increased weight, dehydration, diabetes mellitus

Hepatic

Frequency not reported: Reversible transaminase elevations

Postmarketing reports: Abnormal hepatic function (increased transaminases, alkaline phosphatase, GGT, bilirubin), cholestasis, hepatitis

Hypersensitivity

Frequency not reported: Allergic reactions/delayed allergic reactions

Postmarketing reports: Hypersensitivity, anaphylactic shock

Hematologic

Frequency not reported: Lymphadenopathy

Postmarketing reports: Thrombocytopenia, hemolytic anemia

Renal

Frequency not reported: Cystitis

Postmarketing reports: Glomerulonephritis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Cetirizine Hydrochloride (www.drugs.com/cetirizine.html).

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