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Carvedilol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).
Carvedilol is used to treat heart failure and hypertension (high blood pressure). It is also used after a heart attack that has caused your heart not to pump as well.
Carvedilol may also be used for purposes not listed in this medication guide.
You should not take carvedilol if you have asthma, bronchitis, emphysema, severe liver disease, or a serious heart condition such as heart block, "sick sinus syndrome," or slow heart rate (unless you have a pacemaker).
Avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol (Coreg CR). Also avoid taking medicines or other products that might contain alcohol. Alcohol may cause the carvedilol in Coreg CR to be released too quickly into the body.
If you are being treated for high blood pressure, keep using carvedilol even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
You should not take carvedilol if you are allergic to it, or if you have:
asthma, bronchitis, emphysema;
severe liver disease; or
a serious heart condition such as heart block, "sick sinus syndrome," or slow heart rate (unless you have a pacemaker).
To make sure carvedilol is safe for you, tell your doctor if you have:
diabetes (taking carvedilol can make it harder for you to tell when you have low blood sugar);
angina (chest pain);
liver or kidney disease;
a thyroid disorder;
pheochromocytoma (tumor of the adrenal gland);
circulation problems (such as Raynaud's syndrome); or
a history of allergies.
FDA pregnancy category C. It is not known whether carvedilol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether carvedilol passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking carvedilol.
Take carvedilol exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Carvedilol works best if you take it with food.
You may open the carvedilol capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Discard the empty capsule.
Take carvedilol at the same time every day. Do not skip doses or stop taking carvedilol without first talking to your doctor. Stopping suddenly may make your condition worse.
If you are switched from carvedilol tablets to carvedilol extended-release capsules (Coreg CR), your daily total dose of this medicine may be higher or lower than before. Older adults may be more likely to become dizzy or feel faint when switching from tablets to extended-release capsules. Follow your doctor's instructions.
Your blood pressure will need to be checked often.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
If you need surgery, tell the surgeon ahead of time that you are using carvedilol. You may need to stop using the medicine for a short time.
You should not stop using carvedilol suddenly. Stopping suddenly may make your condition worse.
Carvedilol can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using carvedilol before surgery unless your surgeon tells you to.
Carvedilol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.
Store at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, and seizure (convulsions).
Carvedilol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can further lower your blood pressure and may increase certain side effects of carvedilol. You should especially avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol (Coreg CR).
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Get emergency medical help if you have any of these signs of an allergic reaction to carvedilol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
a light-headed feeling, like you might pass out;
slow or uneven heartbeats;
swelling, rapid weight gain, feeling short of breath (even with mild exertion);
cold feeling or numbness in your fingers or toes;
chest pain, dry cough, wheezing, chest tightness, trouble breathing; or
high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss).
Common carvedilol side effects may include:
weakness, dizziness;
diarrhea;
dry eyes;
tired feeling; or
weight gain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Other drugs may interact with carvedilol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use carvedilol only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Carvedilol (www.drugs.com/carvedilol.html).
Commonly reported side effects of carvedilol include: hyperglycemia. Other side effects include: angina pectoris, hypotension, nausea, orthostatic hypotension, rales, visual disturbance, and vomiting. See below for a comprehensive list of adverse effects.
Applies to carvedilol: oral capsule extended release, oral tablet
Along with its needed effects, carvedilol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking carvedilol:
More common
Less common
Incidence not known
Some side effects of carvedilol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Applies to carvedilol: oral capsule extended release, oral tablet
Common (1% to 10%): Weight increase, hypercholesterolemia, impaired blood glucose control (hyperglycemia, hypoglycemia) in patients with preexisting diabetes, gout, BUN increased, dehydration, hypervolemia
Very common (10% or more): Chest pain (15%), hypotension, cardiac failure
Common (1% to 10%): Bradycardia, edema, hypervolemia, orthostatic hypotension, hypertension, syncope, disturbances of peripheral circulation (e.g., cold extremities, peripheral vascular disease, exacerbation of intermittent claudication, Raynaud's phenomenon)
Uncommon (0.1% to 1%): Atrioventricular block, angina pectoris, tachycardia
Rare (less than 0.1%): Complete AV block, bundle branch block, myocardial ischemia, cerebrovascular disorder
Uncommon (0.1% to 1%): Allergic exanthema, dermatitis, urticaria, pruritus, psoriatic and lichen planus like skin lesions, increased sweating, alopecia, erythematous rash, maculopapular rash, photosensitivity reaction
Rare (less than 0.1%): Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme
Common (1% to 10%): Nausea, diarrhea, vomiting, dyspepsia, abdominal pain, melena, periodontitis
Common (1% to 10%): Urinary tract infection, micturition disorders, hematuria
Uncommon (0.1% to 1%): Erectile dysfunction
Postmarketing reports: Urinary incontinence in women
The frequency of adverse reactions is not dose-dependent, with the exception of dizziness, abnormal vision and bradycardia.
Common (1% to 10%): Anemia, purpura, prothrombin decrease
Rare (0.01% to 0.1%): Thrombocytopenia, aplastic anemia
Very rare (less than 0.01%): Leukopenia
Very rare (less than 0.01%): Alanine aminotransferase (ALT) increased, aspartate aminotransferase (AST) increased, gamma-glutamyltransferase (GGT) increased
Rare (less than 0.1%): Hypersensitivity reactions (including anaphylactic reactions, angioedema, and urticaria)
Common (1% to 10%): Pain in extremities, back pain, arthralgia, myalgia
Common (1% to 10%): Dizziness, headache, hyperesthesia, vertigo
Uncommon (0.1% to 1%): Presyncope, syncope, paresthesia,
Rare (0.01% to 0.1%): Convulsions, migraine, neuralgia, paresis, hypokinesia, neuralgia
Common (1% to 10%): Visual impairment, abnormal vision, blurred vision, lacrimation decreased (dry eye), eye irritation
Very common (10% or more): Fatigue (24%), asthenia
Common (1% to 10%): Pain, malaise, fever
Uncommon (0.1% to 1%): Tinnitus
Common (1% to 10%): Depression, depressed mood, somnolence
Uncommon (0.1% to 1%): Sleep disorders, confusion, impaired concentration, abnormal thinking, paranoia, emotional lability, nervousness
Common (1% to 10%): Renal failure and renal function abnormalities (in patients with diffuse vascular disease and/or underlying renal insufficiency), albuminuria
Very common (10% or more): Upper respiratory tract infection (18%)
Common (1% to 10%): Bronchitis, pneumonia, dyspnea, pulmonary edema, asthma (in predisposed patients), sinusitis, pharyngitis, rhinitis, cough, rales
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Carvedilol (www.drugs.com/carvedilol.html).
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