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Note: This document contains side effect information about sucralfate. Some of the dosage forms listed on this page may not apply to the brand name Carafate.For the Consumer
Applies to sucralfate: oral suspension, oral tablet
Along with its needed effects, sucralfate (the active ingredient contained in Carafate) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking sucralfate:
Incidence not known
Some side effects of sucralfate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For Healthcare Professionals
Applies to sucralfate: compounding powder, oral suspension, oral tabletGeneral
The most commonly reported side effect was constipation.Gastrointestinal
Common (1% to 10%): Constipation
Uncommon (0.1% to 1%): Dry mouth, nausea
Rare (0.01% to 0.1%): Bezoar formation
Frequency not reported: Diarrhea, flatulence, gastric discomfort, indigestion, vomiting
Postmarketing reports: Lip swelling, mouth edema
Bezoars were reported in patients with enteral feedings, delayed gastric emptying, and/or low birthweight neonates.Nervous system
Encephalopathy occurred in patients with chronic renal impairment and/or on long-term treatment.
Cerebral emboli occurred in patients receiving IV administration.
Common (1% to 10%): Headache
Frequency not reported: Dizziness, drowsiness/sleepiness, encephalopathy, vertigo
Postmarketing reports: Cerebral emboliDermatologic
Uncommon (0.1% to 1%): Urticaria
Rare (0.01% to 0.1%): Rash
Frequency not reported: Pruritus
Postmarketing reports: Face edemaMusculoskeletal
Osteodystrophy and osteomalacia occurred in patients with chronic renal impairment and/or on long-term treatment.
Frequency not reported: Back pain, osteodystrophy, osteomalaciaHypersensitivity
Frequency not reported: Anaphylactic reaction, hypersensitivity reactionsRespiratory
Pulmonary edema occurred after IV administration.
Frequency not reported: Dyspnea
Postmarketing reports: Bronchospasm, laryngeal edema, pharyngeal edema, pulmonary emboli, respiratory tract edemaOther
Frequency not reported: Thirst
Postmarketing reports: Face edemaHematologic
Anemia occurred in patients with chronic renal impairment and/or on long-term treatment.
Frequency not reported: AnemiaPsychiatric
Frequency not reported: InsomniaMetabolic
Frequency not reported: HyperglycemiaCardiovascular
Frequency not reported: Edema
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