CapCof Side Effects
Note: This document contains side effect information about chlorpheniramine / codeine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name CapCof.
For the Consumer
Applies to chlorpheniramine/codeine/phenylephrine: oral syrup
For all patients taking this drug:
- This drug has an opioid drug in it. Opioid drugs can put you at risk for addiction, abuse, and misuse. Misuse or abuse of this drug can
lead to overdose and death. If you have questions, talk with your doctor.
- This drug has an opioid drug in it. Severe side effects have happened when opioid drugs were used with benzodiazepines or other drugs
that may make you drowsy or slow your actions. This includes slow or troubled breathing and death. Benzodiazepines include drugs like
alprazolam, diazepam, and lorazepam. Benzodiazepines may be used to treat many health problems like anxiety, trouble sleeping, or seizures.
If you have questions, talk with your doctor.
- Many drugs interact with this drug and can raise the chance of side effects like deadly breathing problems. Talk with your doctor and
pharmacist to make sure it is safe to use this drug with all of your drugs.
- Avoid alcohol or other drugs and natural products that slow your actions.
- Get medical help right away if you feel very sleepy, very dizzy, or if you pass out. Caregivers or others need to get medical help right
away if the patient does not respond, does not answer or react like normal, or will not wake up.
- Very bad and sometimes deadly breathing problems have happened with this drug. Talk with the doctor.
- Get medical help right away if you have slow breathing, shallow breathing, or trouble breathing.
- This drug is not for use in children younger than 18 years of age. The benefits of taking this drug for a cough due to allergies, a cold,
or other infection do not outweigh the risks in children. If your child has been given this drug or if you have any questions, talk with your
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your
doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing;
tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue,
- Very bad dizziness or passing out.
- Chest pain or pressure or a fast heartbeat.
- Trouble breathing, slow breathing, or shallow breathing.
- Noisy breathing.
- Feeling very sleepy.
- Feeling confused.
- A heartbeat that does not feel normal.
- Hallucinations (seeing or hearing things that are not there).
- Mood changes.
- Very bad belly pain.
- Very bad headache.
- Trouble passing urine.
- Change in eyesight.
- Very upset stomach or throwing up.
- Very bad constipation.
- Feeling very tired or weak.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical
help if any of these side effects or any other side effects bother you or do not go away:
- Feeling nervous and excitable.
- Not able to sleep.
- Feeling sleepy.
- Upset stomach or throwing up.
- Sweating a lot.
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical
advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to chlorpheniramine/codeine/phenylephrine: oral liquid
Frequency not reported: Hypotension, palpitations, tachycardia, extra systoles
Frequency not reported: Anaphylactic shock, excessive perspiration, chills
Frequency not reported: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation
Frequency not reported: Thickening of bronchial secretions, tightness of chest, wheezing, nasal stuffiness, and dryness of mouth, nose and throat
Frequency not reported: Urticaria, drug rash, photosensitivity, pruritus
Frequency not reported: Confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, hysteria
Frequency not reported: Sedation, dizziness, sleepiness, disturbed coordination, paresthesia, neuritis, tinnitus, convulsions
Frequency not reported: Blurred vision, diplopia
Frequency not reported: Urinary frequency, difficult urination, urinary retention, early menses
Frequency not reported: Vertigo, fatigue, acute labyrinthitis
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about CapCof (chlorpheniramine / codeine / phenylephrine)
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- Drug class: upper respiratory combinations
- FDA Alerts (5)
Editorial References and Review
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Capcof (www.drugs.com/cdi/capcof.html).