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Calcium chloride Prescription
Generic Name: Calcium Chloride (KAL see um KLOR ide)
Easy-to-read patient leaflet for Calcium Chloride. Includes indications, proper use, special instructions, precautions, and possible side effects.
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Calcium Chloride Drug Information:

This is not a list of all drugs or health problems that interact with calcium chloride. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take calcium chloride with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use calcium chloride as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

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Calcium Chloride Side Effects

For the Consumer

Applies to calcium chloride: intravenous solution

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Dizziness or passing out.
  • Mood changes.
  • Change in how much urine is passed.
  • A heartbeat that does not feel normal.
  • Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.
  • This drug may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Bad taste in your mouth.
  • Hot flashes.
  • Not hungry.
  • Upset stomach or throwing up.
  • Constipation.
  • Feeling tired or weak.
  • More thirst.
  • Bone pain.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to calcium chloride: compounding powder, injectable solution, intravenous solution


Rapid injection may cause tingling sensations, calcium taste, sense of oppression and "heat wave".

Precipitations of ceftriaxone-calcium salt, including fatalities, have been seen in newborns under 28 days old, both pre-term and full term, treated with intravenous ceftriaxone and calcium. The precipitates were found in lungs and kidneys. Newborns have a low blood volume and ceftriaxone has a longer half-life in them, leading to a high precipitation risk.

Frequency not reported: Tingling sensations, calcium taste, sense of oppression, "heat wave, soft tissue calcification, precipitations of ceftriaxone-calcium salt


Frequency not reported: Peripheral vasodilatation, moderate fall in blood pressure, hypertension, venous thrombosis, flushing, bradycardia, arrhythmias

Nervous system

Frequency not reported: Drowsiness, tingling sensation, calcium taste


Frequency not reported: Local burning sensation, venous irritation, necrosis


Frequency not reported: Sloughing, sweating


Frequency not reported: Nephrocalcinosis


Frequency not reported: Muscle weakness, bone pain


Frequency not reported: Anorexia, polydipsia


Frequency not reported: Mental disturbances


Frequency not reported: Polyuria


Frequency not reported: Vomiting, constipation, abdominal pain, nausea, mild gastrointestinal disturbances and irritation

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

Source: Drugs.com Calcium Chloride (www.drugs.com/cdi/calcium-chloride.html).