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Calcitriol is a form of vitamin D.
Calcitriol topical (for the skin) is used to treat plaque psoriasis (raised, silvery flaking of the skin) in adults.
Calcitriol topical is not for use in treating severe forms of psoriasis (with pus, skin peeling, severe redness).
Calcitriol topical may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Tell your doctor if you have ever had:
low or high levels of calcium in your blood;
a calcium disorder or metabolic imbalance; or
if you are receiving UV light treatments (phototherapy) for your psoriasis.
Tell your doctor if you are pregnant or breastfeeding.
Calcitriol topical is not approved for use by anyone younger than 18 years old.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Do not take by mouth. Topical medicine is for use only on the skin. Do not use calcitriol topical on your lips or face, or around your eyes.
Wash your hands before and after applying calcitriol, unless you are using it to treat psoriasis on your hands.
Apply a thin layer of the medication and rub it in completely.
Do not cover treated skin areas unless your doctor has told you to.
Calcitriol topical is for use only on areas of psoriasis. Avoid getting it on healthy skin areas.
Store at room temperature away from moisture and heat. Do not freeze or refrigerate.
Do not share this medicine with another person, even if they have the same symptoms you have.
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
calcitriol could make your skin more sensitive to harmful effects of the sun. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Avoid getting this medicine in your eyes or mouth, or in your vagina.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
blistering, or severe redness, itching, or other irritation of treated areas; or
worsened symptoms or no improvement in psoriasis.
Using calcitriol topical can affect your body's ability to metabolize calcium. Tell your doctor right away if you have symptoms of high levels of calcium in your blood (hypercalcemia), including:
nausea, vomiting, loss of appetite, constipation;
increased thirst or urination;
lack of energy, feeling tired;
muscle weakness;
confusion; or
bone pain.
Common side effects may include:
calcium in your urine;
itching; or
abnormal lab tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Psoriasis:
Ointment: Apply to affected areas twice a day, morning and evening
Comments:
-The maximum weekly dose should not exceed 200 g.
Use: Treatment of mild to moderate plaque psoriasis in adults 18 years and older
Tell your doctor about all your other medicines, especially:
other medicines to treat psoriasis;
vitamin or mineral supplements that contain calcium or vitamin D; or
a diuretic or "water pill" (such as hydrochlorothiazide, HCTZ, Diovan HCT, Hyzaar, Maxzide, Tenoretic, Zestoretic, and others).
This list is not complete. Other drugs may affect calcitriol topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Calcitriol (www.drugs.com/mtm/calcitriol-topical.html).
Commonly reported side effects of calcitriol topical include: hypercalcemia. See below for a comprehensive list of adverse effects.
Applies to calcitriol topical: external ointment
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Applies to calcitriol topical: topical ointment
Very common (10% or more): Hypercalcemia (16% to 24%)
Common (1% to 10%): Laboratory test abnormality
Common (1% to 10%): Skin discomfort, pruritus, skin irritation, erythema, psoriasis
Uncommon (0.1% to 1%): Dry skin
Frequency not reported: Skin edema, contact dermatitis
Postmarketing reports: Acute blistering dermatitis, erythema, skin burning sensation
Common (1% to 10%): Urine abnormality, hypercalciuria
Uncommon (0.1% to 1%): Kidney stones
The most commonly reported side effect was hypercalcemia.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Calcitriol (www.drugs.com/mtm/calcitriol-topical.html).
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