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Caffeine is a central nervous system stimulant. It works by stimulating the brain. Caffeine is found naturally in foods and beverages such as coffee, tea, colas, energy and chocolate. Botanical sources of caffeine include kola nuts, guarana, and yerba mate. Caffeine is also available in prescription and non-prescription medications.
Caffeine is used to restore mental alertness or wakefulness during fatigue or drowsiness. Caffeine is also found in some headache and migraine medications, in certain dietary supplements used for weight loss, and in many popular energy drinks.
Caffeine citrate (Cafcit) is available by prescription only. It is used for short-term treatment of neonatal apnea (breathing problems).
Caffeine may also be used for other conditions as determined by your health care provider.
This is NOT a complete drug interaction list. Check with your health care provider before you start, stop, or change the dose of any medicine. A complete drug interaction check should be completed prior to your use of caffeine or any medication.
Ask your health care provider any questions you may have about how to use caffeine.
Seek medical attention right away if any of these severe side effects occur:
This is not a complete list of all side effects that may occur. Call your health care provider for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Caffeine side effects
Symptoms of overdose may include agitation; anxiety; confusion; frequent urination; irregular or fast heartbeat; muscle twitching; ringing in the ears; seizures; stomach pain; trouble sleeping.
Store caffeine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep caffeine out of the reach of children and away from pets.
This information is a summary only. Consult with your health care provider for additional questions or concerns about the use of caffeine.
1. Caffeine tablet [package insert]. Woonsocket, RI; CVS Pharmacy. 2011 August
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Other brands: NoDoz, Vivarin, Cafcit, Stay Awake, ... +2 more
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Caffeine Citrate (www.drugs.com/caffeine.html).
More frequently reported side effects include: necrotizing enterocolitis. See below for a comprehensive list of adverse effects.
Applies to caffeine: oral solution, oral tablet
Other dosage forms:
Along with its needed effects, caffeine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking caffeine:
More common
Less common
Get emergency help immediately if any of the following symptoms of overdose occur while taking caffeine:
Symptoms of overdose
Some side effects of caffeine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Applies to caffeine: compounding powder, intravenous solution, oral gum, oral liquid, oral tablet, oral tablet dispersible, oral tablet extended release
Very common (10% or more): Constipation (up to 17.4%)
Common (1% to 10%): Necrotizing enterocolitis, gastritis, GI hemorrhage, gastroesophageal reflux, dilated bowel loops
Frequency not reported: Increased gastric aspirate, GI intolerance, vomiting, regurgitation
Long-term follow-up studies have not shown caffeine to adversely affect neurological development or growth parameters.
Common (1% to 10%): Hemorrhage, tachycardia
Uncommon (0.1% to 1%): Arrhythmia
Frequency not reported: Increased left ventricular output, increased stroke volume, hypertension
Common (1% to 10%): Rash, dry skin, skin breakdown
Common (1% to 10%): Disseminated intravascular coagulation, anemia
Frequency not reported: Decreased hemoglobin
Common (1% to 10%): Kidney failure
Common (1% to 10%): Acidosis, hyperglycemia
Frequency not reported: Hypoglycemia, temporary reduced weight gain, decreased thyroxine
Common (1% to 10%): Cerebral hemorrhage
Uncommon (0.1% to 1%): Convulsions/seizures
Frequency not reported: Irritability, restlessness, jitteriness, tremors, brain injury
Common (1% to 10%): Retinopathy of prematurity
Common (1% to 10%): Perinatal disorder (trace aspirates, feeding intolerances), injection site reaction, sepsis, accidental injury, abnormal healing, infusion site phlebitis and inflammation
Frequency not reported: Failure to thrive, deafness
Common (1% to 10%): Dyspnea, lung edema
Frequency not reported: Tachypnea
Rare (less than 0.1%): Hypersensitivity reaction
Frequency not reported: Increased urine flow rate, increased creatinine clearance, increased sodium and calcium excretion
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Caffeine Citrate (www.drugs.com/caffeine.html).
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