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Beyaz

Generic Name: drospirenone, ethinyl estradiol, and levomefolate (droe SPYE re none, ETH in il ES tra DYE ol, and LEE voe me FOE late )
Brand Names: Beyaz, Safyral
Beyaz (drospirenone, ethinyl estradiol and levomefolate calcium) is used to for birth control. Includes Beyaz side effects, interactions and indications.

Average Savings for drospirenone/ethinyl estr (generic): 16.35%
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Drug Information:
BeYaz contains a combination of drospirenone, ethinyl Estradiol, and levomefolate. Drospirenone and ethinyl Estradiol prevent ovulation (the release of an egg from an ovary) and also cause changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus. Levomefolate is a type of B vitamin that helps prevent a rare birth defect that could occur in a baby if pregnancy occurs while taking birth control pills or shortly after stopping them. Learn more

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Beyaz Side Effects

Beyaz Side Effects

Note: This document contains side effect information about drospirenone / ethinyl estradiol / levomefolate calcium. Some of the dosage forms listed on this page may not apply to the brand name Beyaz.

In Summary

Common side effects of Beyaz include: headache and spotting. Other side effects include: irregular menses and migraine. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to drospirenone / ethinyl estradiol / levomefolate calcium: oral tablet

Warning

Oral route (Tablet)

Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs should not be used by women who are over 35 years of age and smoke.

Along with its needed effects, drospirenone / ethinyl estradiol / levomefolate calcium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking drospirenone / ethinyl estradiol / levomefolate calcium:

More common

  • Breast pain or tenderness
  • headache, severe and throbbing
  • heavy non-menstrual vaginal bleeding
  • irregular menstrual periods
  • nausea
  • normal menstrual bleeding occurring earlier, possibly lasting longer than expected

Less common

  • Longer or heavier menstrual periods
  • unusual tiredness or weakness
  • vomiting

Incidence not known

  • Chills
  • clay-colored stools
  • dark urine
  • difficulty with breathing
  • dizziness
  • fever
  • headache
  • itching
  • loss of appetite
  • pain in the chest, groin, or legs, especially the calves
  • rash
  • slurred speech
  • stomach pain
  • sudden loss of coordination
  • sudden, severe weakness or numbness in the arm or leg
  • unpleasant breath odor
  • unusual tiredness or weakness
  • vision changes
  • vomiting of blood
  • yellow eyes or skin

Some side effects of drospirenone / ethinyl estradiol / levomefolate calcium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Crying
  • decreased interest in sexual intercourse
  • delusions of persecution, mistrust, suspiciousness, or combativeness
  • false or unusual sense of well-being
  • inability to have or keep an erection
  • irritability
  • loss in sexual ability, desire, drive, or performance
  • mental depression
  • quick to react or overreact emotionally
  • rapidly changing moods
  • weight gain

For Healthcare Professionals

Applies to drospirenone / ethinyl estradiol / levomefolate calcium: oral tablet

General

The more commonly reported adverse events include menstrual irregularities, nausea/vomiting, breast pain/tenderness, and headache/migraine.

Cardiovascular

Postmarketing reports: Venous and arterial thromboembolic events (including pulmonary emboli, deep vein thrombosis, cerebral thrombosis, retinal thrombosis, myocardial infarction and stroke), hypertension (including hypertensive crisis)

Genitourinary

Combination Oral Contraceptives:

-Very Common (10% or more): Menstrual irregularities (up to 24.9%)

-Frequency not reported: Menstrual irregularities including vaginal hemorrhage (primarily spotting), metrorrhagia, menorrhagia, breast tenderness, decreased libido, unscheduled (breakthrough or intracyclic) bleeding

The average number of episodes of bleeding per 90 days was 3.2 in Cycles 4 to 6; the average number of bleeding and/or spotting days was 15.1 days. The intensity of bleeding based on the ratio of spotting-only days versus total bleeding and/or spotting days was 5.2/15.1 day.

Gastrointestinal

Common (1% to 10%): Nausea, vomiting,

Postmarketing reports: Gallbladder disease, inflammatory bowel disease

Hypersensitivity

Postmarketing reports: Hypersensitivity including anaphylactic reaction

Hepatic

Postmarketing reports: Liver function disturbances, liver tumors

Metabolic

Postmarketing reports: Hyperkalemia, hypertriglyceridemia, changes in glucose tolerance or effect on peripheral insulin resistance (including diabetes mellitus)

Nervous system

Common (1% to 10%): Migraine, headaches

Ocular

Postmarketing reports: Retinal thrombosis

Psychiatric

Frequency not reported: Irritability, depression, affect lability

Oncologic

Frequency not reported: Cervix carcinoma stage 0

Postmarketing reports: Cervical dysplasia

Musculoskeletal

Postmarketing reports: Systemic lupus erythematosus

Dermatologic

Postmarketing reports: Chloasma, angioedema, erythema nodosum, erythema multiforme

Other

Common (1% to 10%): Fatigue

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Beyaz (www.drugs.com/beyaz.html).