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Note: This document contains side effect information about lorazepam. Some of the dosage forms listed on this page may not apply to the brand name Ativan.
In SummaryCommon side effects of Ativan include: sedated state. Other side effects include: dizziness. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to lorazepam: oral solution, oral tablet
Other dosage forms:
Oral route (Tablet)
Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve use where alternative treatments are inadequate. Limit the dosage and duration, and monitor signs and symptoms.
Along with its needed effects, lorazepam (the active ingredient contained in Ativan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lorazepam:
More common
Incidence not known
Get emergency help immediately if any of the following symptoms of overdose occur while taking lorazepam:
Symptoms of overdose
Some side effects of lorazepam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
For Healthcare Professionals
Applies to lorazepam: compounding powder, injectable solution, intravenous solution, oral concentrate, oral tablet
GeneralOral: The most commonly reported side effects included sedation, dizziness, weakness, and unsteadiness.
Parenteral: The most commonly reported side effects included somnolence, respiratory failure, hypotension, and injection site reactions (pain and burning).
LocalParenteral:
Very common (10% or more): Burning (up to 17%), pain (up to 17%)
Common (1% to 10%): Painful response, redness
Uncommon (0.1% to 1%): Injection site reaction
Frequency not reported: Arteriospasm, gangrene, injection site tolerance
Nervous systemOral:
Very common (10% or more): Sedation (up to 15.9%)
Common (1% to 10%): Anterograde amnesia, ataxia, daytime drowsiness, dizziness, unsteadiness
Rare (0.01% to 0.1%): Dysarthria, headache, memory impairment, reduced alertness, slurred speech, transient anterograde amnesia
Very rare (less than 0.01%): Coma, extrapyramidal reactions, tremor
Frequency not reported: Amnesia, autonomic manifestations, convulsions/seizures, drowsiness, extremity numbness/tingling, hyperreflexia, hypersensitivity to light/noise/sound, involuntary movements, short-term memory loss, vertigo
Parenteral:
Common (1% to 10%): Coma, excessive drowsiness/sleepiness, headache, sedation, somnolence, stupor
Uncommon (0.1% to 1%): Brain edema, convulsion, myoclonus, tremor
Frequency not reported: Dizziness
Postmarketing reports: Amnesia, neuroleptic malignant syndrome, paralysis
OtherOral:
Common (1% to 10%): Asthenia, fatigue, weakness
Uncommon (0.1% to 1%): Chills
Very rare (less than 0.01%): Hypothermia
Frequency not reported: Hyperacusis, hyperthermia, paradoxical reactions, rebound phenomena
Parenteral:
Common (1% to 10%): Asthenia, crying, fatigue, sobbing
Frequency not reported: Depressed hearing, falls, hypothermia, paradoxical reactions, tinnitus
Postmarketing reports: Fatalities
PsychiatricOral:
Rare (0.01% to 0.1%): Change in libido, confusion, decreased orgasm, depression, disinhibition, euphoria, numbed emotions, sleep disturbances, unmasking of depression
Frequency not reported: Aggression, aggressiveness, agitation, anxiety, catatonia, dependence, delirium, delusion, disorientation, drug withdrawal symptoms, excitation, hallucinations, hostility, impotence, inappropriate behavior, irritability, insomnia, nightmares, panic attacks, psychoses, rage, restlessness, sexual arousal, suicidal attempt/ideation, tension
Parenteral:
Common (1% to 10%): Confusion, delirium, depression, restlessness, unmasking of depression, visual hallucinations
Uncommon (0.1% to 1%): Abnormal thinking, agitation, ataxia, change in libido, decreased orgasm, hallucinations
Frequency not reported: Aggression, agitation, anxiety, disinhibition, excitation, euphoria, hostility, inappropriate behavior, insomnia, irritability, mania, psychosis, rage, sexual arousal, sleep disturbances, stimulation, suicidal attempt/ideation
Postmarketing reports: Acute brain syndrome, nervousness
RespiratoryOral:
Rare (0.01% to 0.1%): Apnea, respiratory depression, worsening of obstructive pulmonary disease, worsening of sleep apnea
Parenteral:
Common (1% to 10%): Apnea, hypoventilation, respiratory disorder, respiratory failure
Uncommon (0.1% to 1%): Hyperventilation
Frequency not reported: Airway obstruction
Postmarketing reports: Lung edema, lung hemorrhage, pneumothorax, pulmonary hypertension, respiratory arrest
CardiovascularOral:
Rare (0.01% to 0.1%): Hypotension
Frequency not reported: Palpitations, small decreases in blood pressure
Parenteral:
Common (1% to 10%): Hypotension
Postmarketing reports: Arrhythmia, bradycardia, heart arrest/failure, heart block, pericardial effusion, tachycardia, ventricular arrhythmia
MusculoskeletalOral:
Frequency not reported: Muscle pain
Parenteral:
Common (1% to 10%): Muscle weakness
GastrointestinalOral:
Rare (0.01% to 0.1%): Constipation, nausea, salivation changes
Frequency not reported: Abdominal cramps, dry mouth, gastrointestinal symptoms, hypersalivation, vomiting
Parenteral:
Uncommon (0.1% to 1%): Increased salivation, nausea, vomiting
Frequency not reported: Constipation
Postmarketing reports: Gastrointestinal hemorrhage
MetabolicOral:
Rare (0.01% to 0.1%): Change in appetite, increase in alkaline phosphatase
Very rare (less than 0.01%): Hyponatremia
Frequency not reported: Loss of appetite
Parenteral:
Uncommon (0.1% to 1%): Acidosis, increased alkaline phosphatase
Frequency not reported: Hyponatremia
DermatologicOral:
Rare (0.01% to 0.1%): Allergic dermatitis, rash
Frequency not reported: Allergic skin reactions, alopecia, dermatological symptoms, sweating
Parenteral:
Uncommon (0.1% to 1%): Hypertension, hypotension
Frequency not reported: Allergic skin reactions, alopecia, skin rash
HepaticOral:
Rare (0.01% to 0.1%): Abnormal liver function test values, increase in bilirubin, increase in liver transaminases, jaundice
Parenteral:
Uncommon (0.1% to 1%): Abnormal liver function tests
Postmarketing reports: Liver damage
GenitourinaryOral:
Rare (0.01% to 0.1%): Impotence
Parenteral:
Uncommon (0.1% to 1%): Impotence
Postmarketing reports: Urinary incontinence
ImmunologicParenteral:
Uncommon (0.1% to 1%): infection
RenalParenteral:
Uncommon (0.1% to 1%): Cystitis
OcularOral:
Rare (0.01% to 0.1%): Blurred vision, diplopia, eye function/visual disturbance
Parenteral:
Frequency not reported: Blurred vision, diplopia
HematologicOral:
Very rare (less than 0.01%): Agranulocytosis, leukopenia, pancytopenia, thrombocytopenia
Parenteral:
Frequency not reported: Agranulocytosis, hypochromic anemia, leukocytosis, pancytopenia, thrombocythemia, thrombocytopenia
Postmarketing reports: Coagulation disorder
HypersensitivityOral:
Very rare (less than 0.01%): Anaphylactoid reactions, anaphylaxis, hypersensitivity
Frequency not reported: Hypersensitivity reactions
Parenteral:
Frequency not reported: Anaphylactic reactions, anaphylactoid reactions, angioedema, hypersensitivity reactions
EndocrineOral:
Very rare (less than 0.01%): Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Parenteral:
Frequency not reported: Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Postmarketing reports: Aggravation of pheochromocytoma
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Ativan (www.drugs.com/ativan.html).
March 13, 2021
March 1, 2021
March 1, 2021
May 12, 2020
March 23, 2020
February 9, 2022