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Ascorbic Acid

Ascorbic acid Prescription
Generic Name: ascorbic acid (vitamin C) (as KORE bik AS id)
Brand Name: Acerola, Ascorbic Acid Quick Melts, C/Rose Hips, Cecon, Cemill 500, C-Time, Ester-C, N Ice with Vitamin C, Sunkist Vitamin C, Vasoflex HD, Vicks Vitamin C Drops, Vitamin C, ...show all 24 brand names
Physician reviewed ascorbic acid patient information - includes ascorbic acid description, dosage and directions.
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Ascorbic Acid Drug Information:

Ascorbic acid (vitamin C) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. Vitamin C is important for bones and connective tissues, muscles, and blood vessels. Vitamin C also helps the body absorb iron, which is needed for red blood cell production. Ascorbic acid is used to treat and prevent vitamin C deficiency. Ascorbic acid may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare prOviders about all your medical conditions, allergies, and all medicines you use. Learn more

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Ascorbic Acid Side Effects

For the Consumer

Applies to ascorbic acid: oral capsule, oral capsule extended release, oral liquid, oral powder, oral powder for solution, oral powder for suspension, oral solution, oral tablet, oral tablet chewable, oral tablet extended release, oral wafer

Other dosage forms:

  • intravenous solution
Side effects requiring immediate medical attention

Along with its needed effects, ascorbic acid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking ascorbic acid:

Less common or rare

- with high doses
  • Side or lower back pain
Side effects not requiring immediate medical attention

Some side effects of ascorbic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

- with high doses
  • Diarrhea
  • dizziness or faintness (with the injection only)
  • flushing or redness of skin
  • headache
  • increase in urination (mild)
  • nausea or vomiting
  • stomach cramps

For Healthcare Professionals

Applies to ascorbic acid: compounding powder, injectable solution, intravenous solution, oral capsule, oral gum, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release

Renal

Hyperoxaluria appears to be dose-related.

Renal side effects have included oxalate and urate kidney stones.

Nervous system

Migraine headache has been reported with a daily dose of 6 grams.

The manufacturer reports temporary dizziness and faintness may be associated with too rapid of a rate during intravenous administration.

Nervous system side effects have included dizziness, faintness, fatigue, and headache in less than 1% of patients. Migraine headache has also been reported.

Other

Conditional scurvy is reported to occur following excessive doses of ascorbic acid over a prolonged period of time. The mechanism of action for this condition is thought to be that large doses of ascorbic acid condition the patient over time for rapid clearance of ascorbic acid resulting in scurvy. The plasma levels of ascorbic acid appear to remain within normal limits. The actual existence of conditional scurvy remains controversial.

Other side effects have included flank pain in less than 1% of patients. Conditional scurvy has also been reported.

Gastrointestinal

Gastrointestinal side effects have included nausea, diarrhea, abdominal cramps, and esophagitis.

Nausea, diarrhea, and abdominal cramps appears to be associated with doses exceeding 2 g per day, although there have been some reports with as little as 1 g per day.

Esophagitis appears to be associated with prolonged or increased contact of ascorbic acid tablets with the esophageal mucosa.

Hematologic

Hematologic side effects have included hemolysis.

The majority of hemolysis reports have been associated with patients who have concurrent glucose-6-phosphate dehydrogenase deficiency.

Local

Local side effects have included transient mild soreness at the site of injection.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Ascorbic Acid (www.drugs.com/mtm/ascorbic-acid.html).