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Note: This document contains side effect information about polidocanol. Some of the dosage forms listed on this page may not apply to the brand name Asclera.
Common side effects of Asclera include: hematoma at injection site, hematoma, pain at injection site, and skin discoloration at injection site. Other side effects include: pain. See below for a comprehensive list of adverse effects.
Applies to polidocanol: intravenous foam, intravenous solution
Along with its needed effects, polidocanol (the active ingredient contained in Asclera) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking polidocanol:
Incidence not known
Get emergency help immediately if any of the following symptoms of overdose occur while taking polidocanol:
Symptoms of overdose
Some side effects of polidocanol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Applies to polidocanol: injectable foam, injectable kit, injectable solution
Very common (10% or more): Injection site hematoma (up to 42%), injection site irritation (up to 41%), injection site discoloration (up to 38%), injection site pain (up to 24%), injection site pruritus (up to 19%), injection site warmth (up to 16%)
Common (1% to 10%): Injection site thrombosis (local intravaricose blood clots)
Uncommon (0.1% to 1%): Injection site necrosis, induration, swelling
Very rare (less than 0.01%): Anaphylactic shock
Very rare (less than 0.01%): Asthma attack, dyspnea, chest discomfort, cough
Common (1% to 10%): Neovascularization, hematoma
Uncommon (0.1% to 1%): Thrombophlebitis superficial, phlebitis
Rare (0.01% to 0.1%): Deep vein thrombosis
Very rare (less than 0.01%): Cerebrovascular accident, migraine, pulmonary embolism, syncope vasovagal, circulatory collapse, vasculitis, blood pressure abnormal, heart rate abnormal (tachycardia, bradycardia)
Frequency not reported: Cardiac arrest, palpitations, hot flush
Uncommon (0.1% to 1%): Nerve injury
Very rare (less than 0.01%): Headache, paresthesia (local), loss of consciousness, confusional state, dizziness, aphasia, ataxia, hemiparesis, hypoesthesia oral
Frequency not reported: Migraine
Common (1% to 10%): Rash, ecchymosis, skin hyperpigmentation
Uncommon (0.1% to 1%): Allergic dermatitis, skin reaction, erythema
Very rare (less than 0.01%): Angioedema, generalized urticaria, hypertrichosis (in the area of sclerotherapy)
Very rare (less than 0.01%): dysgeusia, nausea, vomiting
Very common (10% or more): Pain in extremity (up to 65%), limb discomfort (up to 32%)
Very rare (less than 0.01%): Pyrexia, asthenia, malaise