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Alfuzosin is an alpha-adrenergic (AL-fa ad-ren-ER-Jk) blocker that is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).
Alfuzosin may also be used for purposes not listed in this medication guide.
You should not take alfuzosin if you have moderate to severe liver disease.
Many drugs can affect alfuzosin, and some should not be used at the same time. Tell your doctor about all your current medicines and any you start or stop using.
Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially if you take heart or blood pressure medications. Avoid driving or hazardous activity until you know how alfuzosin will affect you.
Call your doctor at once if you feel light-headed feeling, like you might pass out.
You should not take alfuzosin if you are allergic to it, or if you have:
moderate to severe liver disease.
Some medicines can cause unwanted or dangerous effects when used with alfuzosin. Your doctor may change your treatment plan if you also use:
an antibiotic;
antifungal medicine;
heart medication;
antiviral medicine to treat hepatitis C or HIV/AIDS; or
medicines similar to alfuzosin (doxazosin, prazosin, silodosin, tamsulosin, or terazosin).
Tell your doctor if you have ever had:
low blood pressure, especially if caused by taking medications;
liver disease;
kidney disease;
prostate cancer; or
long QT syndrome (in you or a family member).
Alfuzosin can affect your pupils. If you have cataract surgery, tell your surgeon ahead of time that you use alfuzosin.
Alfuzosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.
Alfuzosin is not approved for use by anyone younger than 18 years old.
Your doctor may test your prostate specific antigen (PSA) to check for prostate cancer before you take alfuzosin.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take alfuzosin just after a meal, at the same time each day. Do not take the medicine on an empty stomach.
Swallow the tablet whole and do not crush, chew, or break it.
Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Your blood pressure will need to be checked often.
Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea.
Store at room temperature away from moisture, heat, and light.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Avoid driving or hazardous activity until you know how alfuzosin will affect you. Your reactions could be impaired.
Drinking alcohol with this medicine can cause side effects.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
new or worsening chest pain;
upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
penis erection that is painful or lasts 4 hours or longer.
Common side effects may include:
dizziness;
headache; or
feeling tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Benign Prostatic Hyperplasia:
Extended-release tablet: 10 mg orally once a day immediately after the same meal each day
Tell your doctor about all your current medicines. Many drugs can increase your risk of very low blood pressure while taking alfuzosin, especially:
heart or blood pressure medication;
nitrate medication (such as nitroglycerin); or
sildenafil (Viagra) and other erectile dysfunction medicines.
This list is not complete. Many other drugs can affect alfuzosin, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
Further informationRemember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Alfuzosin Hcl Er (www.drugs.com/mtm/alfuzosin.html).
More frequently reported side effects include: dizziness. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to alfuzosin: oral tablet extended release
Side effects requiring immediate medical attentionAlong with its needed effects, alfuzosin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking alfuzosin:
Rare
Incidence not known
Some side effects of alfuzosin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Incidence not known
For Healthcare Professionals
Applies to alfuzosin: oral tablet extended release
Nervous systemVery common (10% or more): Dizziness (up to 27%), headache (up to 14%), fatigue (up to 14%)
Common (1% to 10%): Syncope, pain
Postmarketing reports: Flushing
RespiratoryVery common (10% or more): Upper respiratory tract infection (up to 14%)
Common (1% to 10%): Bronchitis, sinusitis, pharyngitis
Postmarketing reports: Rhinitis
CardiovascularCommon (1% to 10%): Hypotension or postural hypotension
Postmarketing reports: Tachycardia, chest pain, angina pectoris in patients with preexisting coronary artery disease, atrial fibrillation
GastrointestinalCommon (1% to 10%): Abdominal pain, dyspepsia, constipation, nausea
Postmarketing reports: Diarrhea, vomiting
GenitourinaryCommon (1% to 10%): Impotence
Postmarketing reports: Priapism
OcularFrequency not reported: Intraoperative Floppy Iris Syndrome (IFIS) has been observed in some patients undergoing phacoemulsification cataract surgery while being treated with alpha-1 blockers
HepaticPostmarketing reports: Hepatocellular and cholestatic liver injury (including cases with jaundice leading to drug discontinuation)
DermatologicPostmarketing reports: Rash, pruritus, urticaria, angioedema, toxic epidermal necrolysis
HematologicPostmarketing reports: Thrombocytopenia
MetabolicPostmarketing reports: Edema
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Alfuzosin Hcl Er (www.drugs.com/mtm/alfuzosin.html).
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