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Aggrenox

Generic Name: aspirin and dipyridamole (AS pi rin and dye peer ID a mole)
Brand Names: Aggrenox
Aggrenox (aspirin and dipyridamole) is used to reduce the risk of stroke in people who have had blood clots. Includes Aggrenox side effects, interactions and indications.
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Drug Information:
Aggrenox contains a combination of Aspirin and Ridamole">DipyRidamole. Aspirin belongs to a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that cause pain, fever, and inflammation. Ridamole">DipyRidamole keeps platelets in your blood from sticking together to form clots. Aggrenox is used to reduce the risk of stroke in people who have had blood clots or a "mini-stroke" (also called a transient ischemic attack or TIA). Aggrenox is supplied as a capsule containing 200mg Ridamole">DipyRidamole in extended-release pellets and a round white tablet incorporating immediate-release Aspirin 25mg. Learn more

Pickup / Home Delivery

USARx offers multiple ways to purchase this medication. Choose the Best option for you!

  • Guaranteed Price
    Local Pharmacy Pickup

    Pay this amount and pick up your prescription at ANY Retail pharmacy of your choice! Walgreens, CVS, Walmart, etc.

  • 30-day supply
    90-day supply
    Mail Order Home Delivery

    The easiest way to receive your medications.

Aggrenox Medicare Coverage

Overview

Does Medicare cover Aggrenox?

Yes

98% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Aggrenox co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…

CO-PAY RANGE

FREE – $390

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Aggrenox

Here are some ways that may lower the cost of your aggrenox prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Aggrenox Side Effects

Aggrenox Side Effects

Note: This document contains side effect information about aspirin / dipyridamole. Some of the dosage forms listed on this page may not apply to the brand name Aggrenox.

In Summary

Common side effects of Aggrenox include: abdominal pain, diarrhea, and headache. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to aspirin / dipyridamole: oral capsule extended release

Along with its needed effects, aspirin/dipyridamole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aspirin / dipyridamole:

More common

  • Abdominal or stomach pain
  • vomiting

Less common

  • Bleeding from the rectum
  • bloody mucous or unexplained nosebleeds
  • bloody or black, tarry stools
  • confusion
  • convulsions (seizures)
  • difficulty with breathing
  • difficulty with speaking
  • double vision
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • memory loss
  • pale skin
  • purple or red spots on skin
  • slow speech
  • tightness in the chest
  • troubled breathing (exertional)
  • unusual bleeding or bruising
  • vomiting of blood or material that looks like coffee grounds

Rare

  • Abdominal or stomach fullness
  • blood in the urine
  • chills
  • clay-colored stools
  • collection of blood under the skin
  • cough
  • deep, dark purple bruise
  • gaseous abdominal or stomach pain
  • itching, pain, redness, or swelling of the eye or eyelid
  • loss of appetite
  • nausea
  • noisy breathing
  • recurrent fever
  • skin rash or hives (severe)
  • watering of the eyes
  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking aspirin / dipyridamole:

Symptoms of overdose

  • Blurred vision
  • continuing ringing or buzzing or other unexplained noise in the ears
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast or irregular heartbeat
  • flushes
  • hearing loss
  • restlessness
  • sweating
  • unusual tiredness or weakness
  • warm feeling

Some side effects of aspirin / dipyridamole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Acid or sour stomach
  • belching
  • diarrhea
  • difficulty with moving
  • headache
  • heartburn
  • indigestion
  • muscle pain or stiffness
  • pain, swelling, or redness in the joints
  • stomach discomfort or upset

Less common or rare

  • Back pain
  • burning feeling in the chest or stomach
  • loss of strength or energy
  • rectal pain or swelling
  • sleepiness or unusual drowsiness
  • taste loss
  • tenderness in the stomach area

For Healthcare Professionals

Applies to aspirin / dipyridamole: oral capsule extended release

General

The most common adverse reactions were headache, dizziness, dyspepsia, abdominal pain, nausea, and diarrhea.

Nervous system

Very common (10% or more): Dizziness (up to 29.5%), headache (28.25%/year)

Common (1% to 10%): Convulsions, syncope, amnesia, somnolence, intracranial hemorrhage

Frequency not reported: Coma, paresthesia, cerebral hemorrhage, subarachnoid hemorrhage, tinnitus, taste loss

Postmarketing reports: Cerebral edema, migraine

Aspirin:

Very common (10% or more): Dizziness (29.2%), headache (22.1%/year)

Common (1% to 10%): Convulsions, syncope, amnesia, somnolence

Frequency not reported: Brain edema, lethargy, tinnitus

Dipyridamole:

Very common (10% or more): Dizziness (30.1%), headache (27.91%/year)

Common (1% to 10%): Convulsions, syncope, amnesia, somnolence

Gastrointestinal

Very common (10% or more): Dyspepsia (13.23%/year), abdominal pain (12.62%/year), nausea (11.53%/year)

Common (1% to 10%): Diarrhea, vomiting, rectum hemorrhage, melena, hemorrhoids, gastrointestinal hemorrhage

Frequency not reported: Gastritis, ulceration, perforation, gingival bleeding

Postmarketing reports: Pancreatitis, hematemesis

Aspirin:

Very common (10% or more): Dyspepsia (11.84%/year), abdominal pain (10.38%/year)

Common (1% to 10%): Nausea, diarrhea, vomiting, rectum hemorrhage, melena, hemorrhoids, gastrointestinal hemorrhage

Frequency not reported: Gingival bleeding, gastric ulcer perforation, duodenal ulcer perforation, melena, hematemesis, pancreatitis

Dipyridamole:

Very common (10% or more): Dyspepsia (12.68%/year), diarrhea (11.31%/year), abdominal pain (11.22%/year), nausea (11.18%/year)

Common (1% to 10%): Vomiting, rectum hemorrhage, melena, hemorrhoids, gastrointestinal hemorrhage

Other

Common (1% to 10%): Pain, fatigue, accidental injury, malaise, asthenia

Frequency not reported: Fever, deafness

Postmarketing reports: Hypothermia, chest pain, hearing loss, prolonged pregnancy and labor, stillbirths, lower birth weight infants, antepartum bleeding, postpartum bleeding

Aspirin:

Common (1% to 10%): Pain, fatigue, accidental injury, malaise, asthenia

Frequency not reported: Deafness, prolonged pregnancy, prolonged labor, stillbirth, lower birth weight infants, antepartum hemorrhage, postpartum hemorrhage, pyrexia, hypothermia

Dipyridamole:

Common (1% to 10%): Pain, fatigue, accidental injury, malaise, asthenia

Respiratory

Common (1% to 10%): Coughing, upper respiratory tract infection, epistaxis

Frequency not reported: Hyperpnea, asthma, bronchospasm, hemoptysis, pulmonary edema

Postmarketing reports: Respiratory alkalosis, laryngeal edema, tachypnea, dyspnea

Aspirin:

Common (1% to 10%): Coughing, upper respiratory tract infection, epistaxis

Frequency not reported: Dyspnea, laryngeal edema, hyperventilation, pulmonary edema, tachypnea

Dipyridamole:

Common (1% to 10%): Coughing, upper respiratory tract infection, epistaxis

Hematologic

Common (1% to 10%): Hemorrhage not otherwise specified, anemia, major bleeding

Frequency not reported: Hematoma, hemoglobin decreased, hematocrit decreased, erythrocyte count decreased

Postmarketing reports: Prolongation of prothrombin time, disseminated intravascular coagulation, coagulopathy, thrombocytopenia, aplastic anemia, pancytopenia, thrombocytosis

Aspirin:

Common (1% to 10%): Hemorrhage not otherwise specified, anemia

Frequency not reported: Disseminated intravascular coagulation, coagulopathy

Dipyridamole:

Common (1% to 10%): Hemorrhage not otherwise specified, anemia

Cardiovascular

Common (1% to 10%): Cardiac failure

Frequency not reported: Hypotension, tachycardia, palpitation, arrhythmia, supraventricular tachycardia, flushing

Postmarketing reports: Angina pectoris

Aspirin:

Common (1% to 10%): Cardiac failure

Frequency not reported: Arrhythmia

Dipyridamole:

Common (1% to 10%): Cardiac failure

Dermatologic

Common (1% to 10%): Purpura

Frequency not reported: Pruritus, urticaria

Postmarketing reports: Rash, alopecia, angioedema, Stevens-Johnson syndrome, skin hemorrhages, bruising, ecchymosis, hematoma, allergic vasculitis

Aspirin:

Common (1% to 10%): Purpura

Frequency not reported: Erythema exsudativum multiforme

Dipyridamole:

Common (1% to 10%): Purpura

Metabolic

Common (1% to 10%): Anorexia

Frequency not reported: Hyperglycemia, thirst

Postmarketing reports: Hyperkalemia, metabolic acidosis, hypokalemia, hypoglycemia, dehydration

Aspirin:

Common (1% to 10%): Anorexia

Frequency not reported: Hyperglycemia, thirst, dehydration, hyperkalemia, metabolic acidosis, respiratory alkalosis

Dipyridamole:

Common (1% to 10%): Anorexia

Psychiatric

Common (1% to 10%): Confusion

Frequency not reported: Agitation

Aspirin:

Common (1% to 10%): Confusion

Frequency not reported: Agitation

Dipyridamole:

Common (1% to 10%): Confusion

Musculoskeletal

Common (1% to 10%): Back pain

Postmarketing reports: Rhabdomyolysis

Aspirin:

Common (1% to 10%): Back pain

Frequency not reported: Rhabdomyolysis

Dipyridamole:

Common (1% to 10%): Back pain

Oncologic

Common (1% to 10%): Neoplasm not otherwise specified

Aspirin:

Common (1% to 10%): Neoplasm not otherwise specified

Dipyridamole:

Common (1% to 10%): Neoplasm not otherwise specified

Hepatic

Frequency not reported: Cholelithiasis, jaundice, hepatic function abnormal

Postmarketing reports: Reye's syndrome, hepatitis, hepatic failure

Aspirin:

Frequency not reported: Hepatitis, Reye's syndrome

Renal

Frequency not reported: Renal insufficiency, renal failure

Postmarketing reports: Interstitial nephritis, papillary necrosis

Aspirin:

Frequency not reported: Renal failure, interstitial nephritis, papillary necrosis

Genitourinary

Frequency not reported: Uterine hemorrhage, hematuria

Postmarketing reports: Proteinuria

Aspirin:

Frequency not reported: Proteinuria

Immunologic

Frequency not reported: Allergic reaction

Postmarketing reports: Hypersensitivity, acute anaphylaxis

Aspirin:

Frequency not reported: Anaphylactic reactions

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Aggrenox (www.drugs.com/aggrenox.html).