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Accupril Prescription
Generic Name: quinapril (KWIN a pril)
Brand Names: Accupril
Accupril (quinapril) is used to treat high blood pressure (hypertension) and heart failure. Includes Accupril side effects, interactions and indications.

Average Savings for quinapril hcl (generic): 41.12%
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Accupril Drug Information:

Accupril (quinApril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Accupril is used to treat high blood pressure (hypertension) and heart failure. Accupril may also be used for purposes not listed in this medication guide. Do not use Accupril if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. You should not use quinAprilif you have ever had angioedema. Do not take Accupril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto). Learn more

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Accupril Side Effects

Note: This document contains side effect information about quinapril. Some of the dosage forms listed on this page may not apply to the brand name Accupril.

In Summary

More frequent side effects include: cough. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to quinapril: oral tablet


Oral route (Tablet)

When pregnancy is detected, discontinue quinapril hydrochloride as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.

Along with its needed effects, quinapril (the active ingredient contained in Accupril) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking quinapril:

Less common

  • Blurred vision
  • chest pain
  • confusion
  • diarrhea
  • difficult or labored breathing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • nausea
  • stomach pain
  • sweating
  • tightness in the chest
  • unusual tiredness or weakness
  • vomiting


  • Bleeding gums
  • cold, clammy skin
  • enlarged pupils
  • fast or slow heartbeat
  • increased sensitivity of the skin or eyes to sunlight
  • stiff or sore neck

Some side effects of quinapril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache

Less common

  • Back pain
  • coughing
  • difficulty with moving
  • joint pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • rash
  • swollen joints

For Healthcare Professionals

Applies to quinapril: oral tablet


The most commonly reported side effects were dizziness, increased serum creatinine, increased blood urea nitrogen, cough, dyspnea, nausea, vomiting, and diarrhea.


Uncommon (0.1% to 1%): Chest pain, hypotension, palpitations, vasodilation, tachycardia, heart failure, myocardial infarction, hypertensive crisis, angina pectoris, orthostatic hypotension, cardiac rhythm disturbances, cardiogenic shock


Common (1% to 10%): Increased serum creatinine, increased blood urea nitrogen

Uncommon (0.1% to 1%): Urinary tract infection, acute renal failure/dysfunction, worsening renal failure, proteinuria

Frequency not reported: Increases in blood urea nitrogen and serum creatinine


Uncommon (0.1% to 1%): Hyperkalemia, hyponatremia


Uncommon (0.1% to 1%): Hemolytic anemia, agranulocytosis, thrombocytopenia

Frequency not reported: Neutropenia, decreased hemoglobin, decreased hematocrit


Uncommon (0.1% to 1%): Angioedema of the head, neck, face, extremities, lips, tongue, glottis and/or larynx, intestines; anaphylactoid reactions


Uncommon (0.1% to 1%): Abnormal liver function tests, hepatitis

Rare (less than 0.1%): Hepatic failure (characterized by cholestatic jaundice with progression to fulminant hepatic necrosis and sometimes death)

Frequency not reported: Cholestatic icterus

Nervous system

Common (1% to 10%): Dizziness

Uncommon (0.1% to 1%): Headache, cerebrovascular accident/cerebral hemorrhage, somnolence, vertigo, syncope, nervousness, paresthesia, transient ischemic attacks, tinnitus

Rare (less than 0.1%): Balance disorder


Common (1% to 10%): Nausea, vomiting, diarrhea, dyspepsia, abdominal pain

Uncommon (0.1% to 1%): Flatulence, dry mouth or throat, constipation, gastrointestinal hemorrhage, pancreatitis

Rare (less than 0.1%): Glossitis

Very rare (less than 0.01%): Ileus


Common (1% to 10%): Cough, pharyngitis, dyspnea, rhinitis

Uncommon (0.1% to 1%): Eosinophilic pneumonitis, sinusitis, upper respiratory tract infection, bronchitis

Frequency not reported: Bronchospasm


Uncommon (0.1% to 1%): Myalgia, back pain, arthralgia


Uncommon (0.1% to 1%): Impotence


Uncommon (0.1% to 1%): Depression, insomnia, confusion


Common (1% to 10%): Fatigue, asthenia

Uncommon (0.1% to 1%): Fever, malaise, generalized/peripheral edema


Uncommon (0.1% to 1%): Viral infection


Uncommon (0.1% to 1%): Rash, alopecia, increased sweating, pemphigus, pruritus, exfoliative dermatitis, photosensitivity reaction, dermatopolymyositis

Rare (less than 0.1%): Urticaria, erythema multiforme, pemphigus

Very rare (less than 0.01%): Psoriasis-like efflorescence

Frequency not reported: Stevens Johnson syndrome, epidermal necrolysis


Uncommon (0.1% to 1): Amblyopia

Very rare (less than 0.01%): Blurred vision

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

Source: Drugs.com Accupril (www.drugs.com/accupril.html).