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Amlodipine Besylate

Generic Amvaz, Norvasc

Amlodipine (Norvasc) is an inexpensive drug used to treat angina (chest pain) and high blood pressure (hypertension). It is more popular than comparable drugs. It is available in generic and brand versions. Generic amlodipine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Compare calcium channel blockers.

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Amlodipine Besylate Side Effects

What should I watch for?

Visit your healthcare professional for regular checks on your progress. Check your blood pressure as directed. Ask your healthcare professional what your blood pressure should be and when you should contact him or her.

Do not treat yourself for coughs, colds, or pain while you are using this medicine without asking your healthcare professional for advice. Some medicines may increase your blood pressure.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks; they can make you dizzier.

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Swelling of the ankles or feet

Less common

Difficult or labored breathing


fast, irregular, pounding, or racing heartbeat or pulse

feeling of warmth

redness of the face, neck, arms, and occasionally, upper chest

tightness in the chest


Black, tarry stools

bleeding gums

blistering, peeling, or loosening of the skin

blood in the urine or stools

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort


cold and clammy skin

cold sweats



dark yellow urine


dilated neck veins

dizziness or lightheadedness when getting up from a lying or sitting position

extra heartbeats

extreme fatigue



itching of the skin

joint or muscle pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

numbness and tingling of the face, fingers, or toes

pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion

painful or difficult urination

pale, bluish-colored, or cold hands or feet

pinpoint red or purple spots on the skin

red, irritated eyes

redness of the face, neck, arms, and occasionally, upper chest

redness, soreness or itching skin

shakiness in the legs, arms, hands, or feet

slow or irregular heartbeat

sore throat

sores, ulcers, or white spots on the lips or in the mouth

sores, welting, or blisters

sudden sweating


swelling of the face, fingers, feet, or lower legs

swollen glands

trembling or shaking of the hands or feet

unsteadiness or awkwardness

unusual bleeding or bruising

unusual tiredness or weakness

weak or absent pulses in the legs

weakness in the arms, hands, legs, or feet

weight gain

yellow eyes or skin

Incidence not known

Abdominal or stomach pain

clay-colored stools

difficulty with speaking



loss of appetite

loss of balance control

muscle trembling, jerking, or stiffness



shuffling walk

twisting movements of the body

uncontrolled movements, especially of the face, neck, and back

unpleasant breath odor

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Acid or sour stomach


feeling of warmth



lack or loss of strength

muscle cramps

redness of the face, neck, arms, and occasionally, upper chest

sleepiness or unusual drowsiness

stomach discomfort, upset, or pain


Abnormal dreams


back pain

bad unusual or unpleasant (after) taste

bleeding gums

blistering, crusting, irritation, itching, or reddening of the skin


bloody nose

burning feeling in the chest or stomach

burning while urinating

burning, dry, or itching eyes

change in color of the treated skin

change in sense of smell

change in taste

changes in vision


continuing ringing or buzzing or other unexplained noise in the ears

cracked, dry, or scaly skin

decreased sexual performance or desire


difficulty with moving

difficulty with swallowing

discharge, excessive tearing

double vision

dry mouth

dryness of the skin

excess air or gas in the stomach or intestines

excessive muscle tone

eye pain

feeling of constant movement of self or surroundings

feeling of unreality

feeling unusually cold

flushed, dry skin

fruit-like breath odor

full feeling

general feeling of discomfort or illness

hair loss or thinning of the hair

headache, severe and throbbing

hearing loss

increased appetite

increased hunger

increased sweating

increased thirst

increased urge to urinate during the night

increased urination


irritation in the mouth

lack of feeling or emotion

loose stools

loss of memory

muscle pains or stiffness

muscle tension or tightness

muscle weakness



pains in the stomach, side, or abdomen, possibly radiating to the back

passing gas

problems with memory

redness and swelling of the gums

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid


runny nose

seeing double

sensation of spinning

sense of detachment from self or body

shakiness and unsteady walk



stuffy nose


swollen joints

tenderness in the stomach area


trouble in holding or releasing urine

trouble sleeping



unexplained weight loss

unsteadiness, trembling, or other problems with muscle control or coordination

waking to urinate at night

weight loss

Incidence not known

Swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.